(Q24646998)

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Trypanosoma brucei BRCA2 acts in antigenic variation and has undergone a recent expansion in BRC repeat number that is important during homologous recombination

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Trypanosoma brucei BRCA2 acts in antigenic variation and has undergone a recent expansion in BRC repeat number that is important during homologous recombination (English)

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Trypanosoma brucei

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1 reference

5 February 2019

DNA repair protein BRCA2, putative

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5 February 2019

DNA repair protein BRCA2, putative

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BRCA2 repeat-containing protein, putative

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author name string

Claire L Hartley

1

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Richard McCulloch

2

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language of work or name

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publication date

June 2008

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Molecular Microbiology

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68

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5

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1237-51

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Analysis of the VSG gene silent archive in Trypanosoma brucei reveals that mosaic gene expression is prominent in antigenic variation and is favored by archive substructure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

7 April 2017

Interaction with the BRCA2 C terminus protects RAD51-DNA filaments from disassembly by BRC repeats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

7 April 2017

Draft genome sequence of the sexually transmitted pathogen Trichomonas vaginalis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

7 April 2017

Rec2 interplay with both Brh2 and Rad51 balances recombinational repair in Ustilago maydis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

7 April 2017

Distinct roles for two RAD51-related genes in Trypanosoma brucei antigenic variation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

7 April 2017

CDK-dependent phosphorylation of BRCA2 as a regulatory mechanism for recombinational repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

7 April 2017

RAD51 localization and activation following DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

7 April 2017

Insights into DNA recombination from the structure of a RAD51-BRCA2 complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

7 April 2017

Expression of BRC repeats in breast cancer cells disrupts the BRCA2-Rad51 complex and leads to radiation hypersensitivity and loss of G(2)/M checkpoint control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

7 April 2017

The BRCA2 gene product functionally interacts with p53 and RAD51

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

7 April 2017

The BRC repeats in BRCA2 are critical for RAD51 binding and resistance to methyl methanesulfonate treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

7 April 2017

The Genome of the African Trypanosome Trypanosoma brucei

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

7 April 2017

Full-length archaeal Rad51 structure and mutants: mechanisms for RAD51 assembly and control by BRCA2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

7 April 2017

BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

7 April 2017

Mechanism of homologous recombination: mediators and helicases take on regulatory functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

7 April 2017

Regulation of antigen gene expression in Trypanosoma brucei

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

7 April 2017

Dynamic control of Rad51 recombinase by self-association and interaction with BRCA2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

7 April 2017

RAD51 interacts with the evolutionarily conserved BRC motifs in the human breast cancer susceptibility gene brca2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

7 April 2017

RAB22 and RAB163/mouse BRCA2: proteins that specifically interact with the RAD51 protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

7 April 2017

Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

7 April 2017

Trypanosoma brucei homologous recombination is dependent on substrate length and homology, though displays a differential dependence on mismatch repair as substrate length decreases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

7 April 2017

Involvement of Brca2 in DNA repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

7 April 2017

Sequence homology and microhomology dominate chromosomal double-strand break repair in African trypanosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

27 September 2017

Gene conversion is a convergent strategy for pathogen antigenic variation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

27 September 2017

Leishmania replication protein A-1 binds in vivo single-stranded telomeric DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

27 September 2017

Stabilization of RAD-51-DNA filaments via an interaction domain in Caenorhabditis elegans BRCA2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

27 September 2017

Dss1 interaction with Brh2 as a regulatory mechanism for recombinational repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

27 September 2017

Switching trypanosome coats: what's in the wardrobe?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

27 September 2017

Suppression of the DNA repair defects of BRCA2-deficient cells with heterologous protein fusions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

27 September 2017

What the genome sequence is revealing about trypanosome antigenic variation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

27 September 2017

The frequency and rate of pilin antigenic variation in Neisseria gonorrhoeae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

27 September 2017

The central roles of telomeres and subtelomeres in antigenic variation in African trypanosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

27 September 2017

Probabilistic order in antigenic variation of Trypanosoma brucei

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

27 September 2017

BRCA2 BRC motifs bind RAD51-DNA filaments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

27 September 2017

RAD-51-dependent and -independent roles of a Caenorhabditis elegans BRCA2-related protein during DNA double-strand break repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

27 September 2017

Brh2-Dss1 interplay enables properly controlled recombination in Ustilago maydis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

27 September 2017

Isolation of the repertoire of VSG expression site containing telomeres of Trypanosoma brucei 427 using transformation-associated recombination in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

27 September 2017

BRCA1 and BRCA2: 1994 and beyond

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

27 September 2017

DNA recombination, chromosomal stability and carcinogenesis: insights into the role of BRCA2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

27 September 2017

Emerging functions of BRCA2 in DNA recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

27 September 2017

DNA damage checkpoint and repair centers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

27 September 2017

BRCA2 homolog required for proficiency in DNA repair, recombination, and genome stability in Ustilago maydis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

27 September 2017

Nuclear dynamics of RAD52 group homologous recombination proteins in response to DNA damage.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

27 September 2017

Antigenic variation in trypanosomes: enhanced phenotypic variation in a eukaryotic parasite

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

27 September 2017

The surface structure of trypanosomes in relation to their molecular phylogeny

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

27 September 2017

Role of BRCA2 in control of the RAD51 recombination and DNA repair protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

27 September 2017

Gross chromosomal rearrangements and genetic exchange between nonhomologous chromosomes following BRCA2 inactivation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

27 September 2017

A role for RAD51 and homologous recombination in Trypanosoma brucei antigenic variation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

27 September 2017

Predominance of duplicative VSG gene conversion in antigenic variation in African trypanosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

27 September 2017

Shared themes of antigenic variation and virulence in bacterial, protozoal, and fungal infections.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

27 September 2017

The BRC repeats are conserved in mammalian BRCA2 proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

27 September 2017

Gene conversions mediating antigenic variation in Trypanosoma brucei can occur in variant surface glycoprotein expression sites lacking 70-base-pair repeat sequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

27 September 2017

Pseudogenes, chimaeric genes and the timing of antigen variation in African trypanosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

27 September 2017

Stabilization of RAD51 nucleoprotein filaments by the C-terminal region of BRCA2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

30 May 2018

Internal repeats in the BRCA2 protein sequence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

30 May 2018

High frequency of antigenic variation in Trypanosoma brucei rhodesiense infections

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

30 May 2018

Continuous cultivation of Trypanosoma brucei blood stream forms in a medium containing a low concentration of serum protein without feeder cell layers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

30 May 2018

Cloning and analysis of Trypanosoma (Nannomonas) congolense ILNat 2.1 VSG gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

30 May 2018

Trypanosome variable surface glycoproteins: composite genes and order of expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

30 May 2018

Surface epitope variation via mosaic gene formation is potential key to long-term survival of Trypanosoma brucei

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2408642

30 May 2018

The importance of mosaic genes to trypanosome survival

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2008.06230.X

21 January 2018

Mismatch repair regulates homologous recombination, but has little influence on antigenic variation, in Trypanosoma brucei

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2008.06230.X

21 January 2018

Two pathways of homologous recombination in Trypanosoma brucei

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2008.06230.X

21 January 2018

The taxonomic and phylogenetic relationships of Trypanosoma vivax from South America and Africa.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2008.06230.X

21 January 2018

Interaction between Arabidopsis Brca2 and its partners Rad51, Dmc1, and Dss1.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2008.06230.X

21 January 2018

A novel ISWI is involved in VSG expression site downregulation in African trypanosomes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2008.06230.X

21 January 2018

Sequence fingerprints in BRCA2 and RAD51: implications for DNA repair and cancer

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2008.06230.X

21 January 2018

The molecular karyotype of the megabase chromosomes of Trypanosoma brucei stock 427.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2008.06230.X

21 January 2018

Trypanosoma brucei DMC1 does not act in DNA recombination, repair or antigenic variation in bloodstream stage cells.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2008.06230.X

21 January 2018

Inactivation of Mre11 does not affect VSG gene duplication mediated by homologous recombination in Trypanosoma brucei.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2008.06230.X

21 January 2018

A genetic screen identifies genes and sites involved in pilin antigenic variation in Neisseria gonorrhoeae

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2008.06230.X

21 January 2018

A region of human BRCA2 containing multiple BRC repeats promotes RAD51-mediated strand exchange

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2008.06230.X

21 January 2018

BRCA2-dependent and independent formation of RAD51 nuclear foci.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2008.06230.X

21 January 2018

Structural analysis of the chicken BRCA2 gene facilitates identification of functional domains and disease causing mutations

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2008.06230.X

21 January 2018

The BRCA2 homologue Brh2 nucleates RAD51 filament formation at a dsDNA-ssDNA junction

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2008.06230.X

21 January 2018

Identifiers

10.1111/J.1365-2958.2008.06230.X

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1 reference

Consolidated OpenCitations Corpus – April 2017

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1 reference

Consolidated OpenCitations Corpus – April 2017

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