(Q48555364)

12 February 2018

title

Sequence fingerprints in BRCA2 and RAD51: implications for DNA repair and cancer. (English)

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12 February 2018

4

Tom L Blundell

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12 February 2018

author name string

Thomas Lo

series ordinal

1

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12 February 2018

Luca Pellegrini

series ordinal

2

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12 February 2018

Ashok R Venkitaraman

series ordinal

3

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12 February 2018

publication date

1 September 2003

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12 February 2018

published in

DNA Repair

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12 February 2018

volume

2

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12 February 2018

issue

9

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12 February 2018

page(s)

1015-1028

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12 February 2018

DNA strand exchange proteins: a biochemical and physical comparison.

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Mammalian recombination-repair genes XRCC2 and XRCC3 promote correct chromosome segregation

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The Rad51 paralog Rad51B promotes homologous recombinational repair

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Chromosome instability and defective recombinational repair in knockout mutants of the five Rad51 paralogs

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Involvement of Brca2 in DNA repair

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7 January 2021

THE GENETICS OF BREAST CANCER SUSCEPTIBILITY

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7 January 2021

Breast cancer genetics: what we know and what we need

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7 January 2021

Biallelic inactivation of BRCA2 in Fanconi anemia

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7 January 2021

Purification and characterization of the human Rad51 protein, an analogue of E. coli RecA

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Evolutionary comparisons of RecA-like proteins across all major kingdoms of living organisms

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7 January 2021

The N-terminal domain of the human Rad51 protein binds DNA: structure and a DNA binding surface as revealed by NMR

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7 January 2021

The BRC repeats in BRCA2 are critical for RAD51 binding and resistance to methyl methanesulfonate treatment

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7 January 2021

The BRCA2 gene product functionally interacts with p53 and RAD51

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7 January 2021

BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure

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7 January 2021

Characterization of the split hand/split foot malformation locus SHFM1 at 7q21.3-q22.1 and analysis of a candidate gene for its expression during limb development

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7 January 2021

Interaction between the product of the breast cancer susceptibility gene BRCA2 and DSS1, a protein functionally conserved from yeast to mammals

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7 January 2021

Structure of the RPA trimerization core and its role in the multistep DNA-binding mechanism of RPA

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7 January 2021

Internal repeats in the BRCA2 protein sequence

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7 January 2021

RAD51 interacts with the evolutionarily conserved BRC motifs in the human breast cancer susceptibility gene brca2

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7 January 2021

Insights into DNA recombination from the structure of a RAD51-BRCA2 complex

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7 January 2021

The structure of the E. coli recA protein monomer and polymer

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7 January 2021

Homologous DNA pairing promoted by a 20-amino acid peptide derived from RecA.

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7 January 2021

JOY: protein sequence-structure representation and analysis.

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7 January 2021

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Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

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7 January 2021

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7 January 2021

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7 January 2021

Structural analysis of the chicken BRCA2 gene facilitates identification of functional domains and disease causing mutations

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7 January 2021

BRCA2 homolog required for proficiency in DNA repair, recombination, and genome stability in Ustilago maydis.

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7 January 2021

Interaction between BRCA2 and replication protein A is compromised by a cancer-predisposing mutation in BRCA2

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7 January 2021

Transcriptional activation functions in BRCA2

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7 January 2021

Role of BRCA2 in control of the RAD51 recombination and DNA repair protein.

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7 January 2021

Expression of BRC repeats in breast cancer cells disrupts the BRCA2-Rad51 complex and leads to radiation hypersensitivity and loss of G(2)/M checkpoint control

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7 January 2021

Nuclear foci of mammalian Rad51 recombination protein in somatic cells after DNA damage and its localization in synaptonemal complexes

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7 January 2021

Purification and characterization of replication protein A, a cellular protein required for in vitro replication of simian virus 40 DNA.

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7 January 2021

Rad52 protein associates with replication protein A (RPA)-single-stranded DNA to accelerate Rad51-mediated displacement of RPA and presynaptic complex formation

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7 January 2021

Stimulation by Rad52 of yeast Rad51-mediated recombination

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7 January 2021

Visualisation of human rad52 protein and its complexes with hRad51 and DNA.

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7 January 2021

Binding of double-strand breaks in DNA by human Rad52 protein

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7 January 2021

Analysis of the human replication protein A:Rad52 complex: evidence for crosstalk between RPA32, RPA70, Rad52 and DNA

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7 January 2021

Physical interaction between human RAD52 and RPA is required for homologous recombination in mammalian cells

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7 January 2021

Rad52 protein stimulates DNA strand exchange by Rad51 and replication protein A

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7 January 2021

Function of yeast Rad52 protein as a mediator between replication protein A and the Rad51 recombinase

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7 January 2021

Homologous recombination, but not DNA repair, is reduced in vertebrate cells deficient in RAD52.

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7 January 2021

Targeted inactivation of mouse RAD52 reduces homologous recombination but not resistance to ionizing radiation

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7 January 2021

Rad52 associates with RPA and functions with rad55 and rad57 to assemble meiotic recombination complexes

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https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900097-1

7 January 2021

XRCC3 controls the fidelity of homologous recombination: roles for XRCC3 in late stages of recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900097-1

7 January 2021

XRCC2 and XRCC3, new human Rad51-family members, promote chromosome stability and protect against DNA cross-links and other damages

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900097-1

7 January 2021

Xrcc3 is required for assembly of Rad51 complexes in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900097-1

7 January 2021

10.1016/S1568-7864(03)00097-1

Identifiers

DOI

1 reference

12 February 2018

1 reference

12 February 2018