(Q24652668)

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Centrally active allosteric potentiators of the M4 muscarinic acetylcholine receptor reverse amphetamine-induced hyperlocomotor activity in rats

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18772318%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

Centrally active allosteric potentiators of the M4 muscarinic acetylcholine receptor reverse amphetamine-induced hyperlocomotor activity in rats (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18772318%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

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Patrick R Gentry

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13 January 2020

P. Jeffrey Conn

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P Jeffrey Conn

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13 January 2020

Craig W. Lindsley

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Craig W Lindsley

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13 January 2020

Jana K Shirey-Rice

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Jana K Shirey

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13 January 2020

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Ashley E Brady

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13 January 2020

Micah L Breininger

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Micah L Breininger

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13 January 2020

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Huiyong Yin

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13 January 2020

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Carrie K Jones

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13 January 2020

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Thomas M Bridges

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13 January 2020

J Phillip Kennedy

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13 January 2020

Analisa D Thompson

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13 January 2020

Justin U Heiman

6

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13 January 2020

Satyawan B Jadhav

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13 January 2020

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4 September 2008

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13 January 2020

Journal of Pharmacology and Experimental Therapeutics

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13 January 2020

327

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13 January 2020

3

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13 January 2020

941-953

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13 January 2020

Allosteric modulation of group III metabotropic glutamate receptor 4: A potential approach to Parkinson's disease treatment

1 reference

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7 April 2017

Enhancement of D1 dopamine receptor-mediated locomotor stimulation in M(4) muscarinic acetylcholine receptor knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745822

7 April 2017

Selective muscarinic receptor agonist xanomeline as a novel treatment approach for schizophrenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745822

7 April 2017

Glutamate-based therapeutic approaches: allosteric modulators of metabotropic glutamate receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745822

7 April 2017

A novel assay of Gi/o-linked G protein-coupled receptor coupling to potassium channels provides new insights into the pharmacology of the group III metabotropic glutamate receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745822

28 September 2017

An allosteric potentiator of M4 mAChR modulates hippocampal synaptic transmission

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745822

28 September 2017

Re-emergence of striatal cholinergic interneurons in movement disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745822

28 September 2017

Altered hippocampal muscarinic M4, but not M1, receptor expression from subjects with schizophrenia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745822

28 September 2017

Challenges in the development of mGluR5 positive allosteric modulators: the discovery of CPPHA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745822

28 September 2017

Towards a muscarinic hypothesis of schizophrenia.

1 reference

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28 September 2017

A novel class of positive allosteric modulators of metabotropic glutamate receptor subtype 1 interact with a site distinct from that of negative allosteric modulators

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745822

28 September 2017

Biphenyl-indanone A, a positive allosteric modulator of the metabotropic glutamate receptor subtype 2, has antipsychotic- and anxiolytic-like effects in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745822

28 September 2017

A novel selective positive allosteric modulator of metabotropic glutamate receptor subtype 5 has in vivo activity and antipsychotic-like effects in rat behavioral models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745822

28 September 2017

Discovery of positive allosteric modulators for the metabotropic glutamate receptor subtype 5 from a series of N-(1,3-diphenyl-1H- pyrazol-5-yl)benzamides that potentiate receptor function in vivo

1 reference

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28 September 2017

A novel selective allosteric modulator potentiates the activity of native metabotropic glutamate receptor subtype 5 in rat forebrain

1 reference

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28 September 2017

A family of highly selective allosteric modulators of the metabotropic glutamate receptor subtype 5.

1 reference

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28 September 2017

Muscarinic receptors as a target for drugs treating schizophrenia

1 reference

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28 September 2017

Use of M1-M5 muscarinic receptor knockout mice as novel tools to delineate the physiological roles of the muscarinic cholinergic system

1 reference

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28 September 2017

Cholinergic agonists and the treatment of Alzheimer's disease

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28 September 2017

Elucidating the role of muscarinic receptors in psychosis

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28 September 2017

Effects of xanomeline, a selective muscarinic receptor agonist, on cognitive function and behavioral symptoms in Alzheimer disease

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28 September 2017

Molecular biology of muscarinic acetylcholine receptors

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28 September 2017

The current status of the dopamine hypothesis of schizophrenia

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28 September 2017

M1 muscarinic receptors contribute to, whereas M4 receptors inhibit, dopamine D1 receptor-induced [3H]-cyclic AMP accumulation in rat striatal slices.

1 reference

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28 November 2018

M4 muscarinic receptors regulate the dynamics of cholinergic and dopaminergic neurotransmission: relevance to the pathophysiology and treatment of related CNS pathologies

1 reference

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28 November 2018

Role of specific muscarinic receptor subtypes in cholinergic parasympathomimetic responses, in vivo phosphoinositide hydrolysis, and pilocarpine‐induced seizure activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745822

28 November 2018

The muscarinic receptor agonist xanomeline has an antipsychotic-like profile in the rat.

1 reference

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28 November 2018

Generation and pharmacological analysis of M2 and M4 muscarinic receptor knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745822

28 November 2018

Muscarinic IPSPs in rat striatal cholinergic interneurones

1 reference

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28 November 2018

Protein kinase C as a drug target: implications for drug or diet prevention and treatment of cancer

1 reference

https://api.crossref.org/works/10.1124%2FJPET.108.140350

7 January 2021

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10.1124/JPET.108.140350

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13 January 2020

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13 January 2020

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13 January 2020

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