(Q24652742)

Agata L Starosta

4

0 references

Paola Fucini

Paola Fucini

6

0 references

Frank Schluenzen

Frank Schluenzen

2

0 references

Daniel N. Wilson

Daniel N Wilson

1

0 references

author name string

Joerg M Harms

Proceedings of the National Academy of Sciences of the United States of America

3

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language of work or name

English

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publication date

9 September 2008

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published in

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volume

105

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issue

36

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page(s)

13339-44

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cites work

Alterations at the peptidyl transferase centre of the ribosome induced by the synergistic action of the streptogramins dalfopristin and quinupristin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533191

The oxazolidinone linezolid inhibits initiation of protein synthesis in bacteria

7 April 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533191

7 April 2017

https://api.crossref.org/works/10.1073%2FPNAS.0804276105

inferred from DOI database lookup

7 January 2021

based on heuristic

A new tRNA intermediate revealed on the ribosome during EF4-mediated back-translocation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533191

Mutations Outside the Anisomycin-Binding Site Can Make Ribosomes Drug-Resistant

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533191

Structures of five antibiotics bound at the peptidyl transferase center of the large ribosomal subunit

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533191

Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533191

Structure of the 70S ribosome complexed with mRNA and tRNA

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533191

Structures of the bacterial ribosome at 3.5 A resolution

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533191

The CCP4 suite: programs for protein crystallography

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533191

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

7 April 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533191

7 April 2017

https://api.crossref.org/works/10.1073/PNAS.0804276105

The highly conserved LepA is a ribosomal elongation factor that back-translocates the ribosome

22 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533191

The mechanism of action of DuP 721, a new antibacterial agent: effects on macromolecular synthesis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533191

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533191

The E-site story: the importance of maintaining two tRNAs on the ribosome during protein synthesis.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533191

Species-specific antibiotic-ribosome interactions: implications for drug development

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533191

An induced-fit mechanism to promote peptide bond formation and exclude hydrolysis of peptidyl-tRNA.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533191

Simulating movement of tRNA into the ribosome during decoding

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533191

Effects of a number of classes of 50S inhibitors on stop codon readthrough during protein synthesis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533191

Oxazolidinones: activity, mode of action, and mechanism of resistance.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533191

Cross-linking in the Living Cell Locates the Site of Action of Oxazolidinone Antibiotics

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533191

Oxazolidinone antibiotics target the P site on Escherichia coli ribosomes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533191

Resistance to linezolid: characterization of mutations in rRNA and comparison of their occurrences in vancomycin-resistant enterococci

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533191

Oxazolidinone resistance mutations in 23S rRNA of Escherichia coli reveal the central region of domain V as the primary site of drug action.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533191

Mechanism of action of oxazolidinones: effects of linezolid and eperezolid on translation reactions

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533191

The oxazolidinone eperezolid binds to the 50S ribosomal subunit and competes with binding of chloramphenicol and lincomycin

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533191

Mutations at nucleotides G2251 and U2585 of 23 S rRNA perturb the peptidyl transferase center of the ribosome

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533191

Throwing a spanner in the works: antibiotics and the translation apparatus

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533191

23S ribosomal RNA mutations in halobacteria conferring resistance to the anti-80S ribosome targeted antibiotic anisomycin

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533191

Mechanism of action of DuP 721: inhibition of an early event during initiation of protein synthesis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533191

Chloramphenicol resistance mutations in the single 23S rRNA gene of the archaeon Halobacterium halobium

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533191

Mutational analysis of 16S and 23S rRNA genes of Thermus thermophilus

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533191

Structural basis for the function of the ribosomal L7/12 stalk in factor binding and GTPase activation

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533191

Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance

30 May 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0804276105

Inhibition of peptide bond formation by pleuromutilins: the structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with tiamulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0804276105

Ribosomal RNA is the target for oxazolidinones, a novel class of translational inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0804276105

The site of action of oxazolidinone antibiotics in living bacteria and in human mitochondria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0804276105

Resistance mutations in 23 S rRNA identify the site of action of the protein synthesis inhibitor linezolid in the ribosomal peptidyl transferase center

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0804276105

Ribosomal and non-ribosomal resistance to oxazolidinones: species-specific idiosyncrasy of ribosomal alterations

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0804276105

Linezolid resistance in a clinical isolate of Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0804276105

On the target of a novel class of antibiotics, oxazolidinones, active against multidrug-resistant Gram-positive bacteria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0804276105

The protein synthesis inhibitors, oxazolidinones and chloramphenicol, cause extensive translational inaccuracy in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0804276105

The roles of ribosomal proteins in the structure assembly, and evolution of the large ribosomal subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0804276105

The active site of the ribosome is composed of two layers of conserved nucleotides with distinct roles in peptide bond formation and peptide release.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0804276105

tRNA selection and kinetic proofreading in translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0804276105

Peptidyl-tRNA regulates the GTPase activity of translation factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0804276105

Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0804276105

Mutations in ribosomal protein L3 and 23S ribosomal RNA at the peptidyl transferase centre are associated with reduced susceptibility to tiamulin in Brachyspira spp. isolates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0804276105

21 January 2018

Identifiers

DOI

10.1073/PNAS.0804276105

1 reference

3437042

ADS bibcode

2008PNAS..10513339W

0 references

3437042

1 reference

1 reference

1 reference