(Q24655792)

Membrane topology of human ASBT (SLC10A2) determined by dual label epitope insertion scanning mutagenesis. New evidence for seven transmembrane domains

published in

Molecular Pharmaceutics

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volume

3

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issue

3

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page(s)

223-30

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cites work

1 reference

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The heteromeric organic solute transporter alpha-beta, Ostalpha-Ostbeta, is an ileal basolateral bile acid transporter

7 April 2017

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Transport of bile acids in multidrug-resistance-protein 3-overexpressing cells co-transfected with the ileal Na+-dependent bile-acid transporter

7 April 2017

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Initial sequencing and analysis of the human genome

7 April 2017

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Primary bile acid malabsorption caused by mutations in the ileal sodium-dependent bile acid transporter gene (SLC10A2)

7 April 2017

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Identification of a Mutation in the Ileal Sodium-dependent Bile Acid Transporter Gene That Abolishes Transport Activity

7 April 2017

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The Sequence of the Human Genome

7 April 2017

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Site-directed mutagenesis and use of bile acid-MTS conjugates to probe the role of cysteines in the human apical sodium-dependent bile acid transporter (SLC10A2)

7 April 2017

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Topology scanning and putative three-dimensional structure of the extracellular binding domains of the apical sodium-dependent bile acid transporter (SLC10A2)

7 April 2017

1 reference

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The continuing importance of bile acids in liver and intestinal disease

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2796132

Expression and transport properties of the human ileal and renal sodium-dependent bile acid transporter

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2796132

Interaction of native bile acids with human apical sodium-dependent bile acid transporter (hASBT): influence of steroidal hydroxylation pattern and C-24 conjugation

7 April 2017

1 reference

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Transporters and drug discovery: why, when, and how.

28 September 2017

1 reference

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Transporters and drug therapy: implications for drug disposition and disease

28 September 2017

1 reference

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Development of stably transfected monolayer overexpressing the human apical sodium-dependent bile acid transporter (hASBT).

28 September 2017

1 reference

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hPEPT1 affinity and translocation of selected Gln-Sar and Glu-Sar dipeptide derivatives.

28 September 2017

1 reference

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In vitro and pharmacophore-based discovery of novel hPEPT1 inhibitors

28 September 2017

1 reference

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Comparative pharmacophore modeling of organic anion transporting polypeptides: a meta-analysis of rat Oatp1a1 and human OATP1B1.

28 September 2017

1 reference

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Predicting P-glycoprotein substrates by a quantitative structure-activity relationship model.

28 September 2017

1 reference

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Current perspectives on established and putative mammalian oligopeptide transporters

28 September 2017

1 reference

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Structural biology and function of solute transporters: implications for identifying and designing substrates

28 September 2017

1 reference

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Identification of a region of the ileal-type sodium/bile acid cotransporter interacting with a competitive bile acid transport inhibitor

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2796132

Progress in understanding the structure-activity relationships of P-glycoprotein

28 September 2017

1 reference

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Role of transport proteins in drug absorption, distribution and excretion

28 September 2017

1 reference

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Transport of bile acids in hepatic and non-hepatic tissues.

28 September 2017

1 reference

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Alternative splicing of the rat sodium/bile acid transporter changes its cellular localization and transport properties

28 September 2017

1 reference

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Inhibition of the human sodium/bile acid cotransporters by side-specific methanethiosulfonate sulfhydryl reagents: substrate-controlled accessibility of site of inactivation

28 September 2017

1 reference

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Substrate specificity of the ileal and the hepatic Na(+)/bile acid cotransporters of the rabbit. II. A reliable 3D QSAR pharmacophore model for the ileal Na(+)/bile acid cotransporter

28 September 2017

1 reference

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Hepatobiliary transport of bile acid amino acid, bile acid peptide, and bile acid oligonucleotide conjugates in rats

28 September 2017

1 reference

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Substrate specificity of the ileal and the hepatic Na(+)/bile acid cotransporters of the rabbit. I. Transport studies with membrane vesicles and cell lines expressing the cloned transporters

28 September 2017

1 reference

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Sorting of rat liver and ileal sodium-dependent bile acid transporters in polarized epithelial cells

28 September 2017

1 reference

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Minimal molecular determinants of substrates for recognition by the intestinal peptide transporter

28 September 2017

1 reference

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Molecular modeling of the intestinal bile acid carrier: a comparative molecular field analysis study

28 September 2017

1 reference

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Rat cholangiocytes absorb bile acids at their apical domain via the ileal sodium-dependent bile acid transporter

28 September 2017

1 reference

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Topological photoaffinity labeling of the rabbit ileal Na+/bile-salt-cotransport system

28 September 2017

1 reference

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Enhanced transepithelial transport of peptides by conjugation to cholic acid

28 September 2017

1 reference

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Use of the intestinal bile acid transporter for the uptake of cholic acid conjugates with HIV-1 protease inhibitory activity

28 September 2017

1 reference

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Bile acid transport systems as pharmaceutical targets

28 September 2017

1 reference

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Absolute bioavailability and metabolic disposition of valaciclovir, the L-valyl ester of acyclovir, following oral administration to humans

28 September 2017

1 reference

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Valaciclovir (BW256U87): the L-valyl ester of acyclovir

28 September 2017

1 reference

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Synthesis and biological activity of bile acid-derived HMG-CoA reductase inhibitors. The role of 21-methyl in recognition of HMG-CoA reductase and the ileal bile acid transport system

28 September 2017

1 reference

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Cloning and molecular characterization of the ontogeny of a rat ileal sodium-dependent bile acid transporter

28 September 2017

1 reference

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Bile acid transporters

1 reference

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Cloning and chromosomal localization of the human ileal lipid-binding protein

28 September 2017

1 reference

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Pharmacokinetics of acyclovir after intravenous and oral administration.

28 September 2017

1 reference

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Bile acid solubility and precipitation in vitro and in vivo: the role of conjugation, pH, and Ca2+ ions.

28 September 2017

1 reference

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Liver-specific drug targeting by coupling to bile acids

28 September 2017

1 reference

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Properties and biological significance of the ileal bile salt transport system

28 September 2017

1 reference

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Characterization, cDNA cloning, and functional expression of mouse ileal sodium-dependent bile acid transporter

28 September 2017

1 reference

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30 May 2018

1 reference

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30 May 2018

1 reference

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Metabolic disposition of the acyclovir prodrug valaciclovir in the rat.

30 May 2018

1 reference

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Transport of bile acids in a human intestinal epithelial cell line, Caco-2.

30 May 2018

1 reference

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Computational models for identifying potential P-glycoprotein substrates and inhibitors

30 May 2018

1 reference

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28 November 2018

1 reference

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28 November 2018

1 reference

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1 reference

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Molecular requirements of the human nucleoside transporters hCNT1, hCNT2, and hENT1.

28 November 2018

1 reference

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Influence of molecular structure on substrate binding to the human organic cation transporter, hOCT1.

28 November 2018

1 reference

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Identification of a ligand-binding site in the Na+/bile acid cotransporting protein from rabbit ileum

28 November 2018

1 reference

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Influence of passive permeability on apparent P-glycoprotein kinetics.

28 November 2018

1 reference

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Bile acid-oligodeoxynucleotide conjugates: synthesis and liver excretion in rats

28 November 2018

1 reference

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Modified amino acids and peptides as substrates for the intestinal peptide transporter PepT1.

28 November 2018

1 reference

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5'-Amino acid esters of antiviral nucleosides, acyclovir, and AZT are absorbed by the intestinal PEPT1 peptide transporter

28 November 2018

1 reference

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Carrier-mediated jejunal absorption of conjugated bile acids in the guinea pig.

28 November 2018

1 reference

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Expression cloning and characterization of the hamster ileal sodium-dependent bile acid transporter.

28 November 2018

1 reference

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Evaluation of the bile acid transporter in enhancing intestinal permeability to renin-inhibitory peptides

28 November 2018

1 reference

12 December 2020

Bile acid derived HMG-CoA reductase inhibitors

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12 December 2020

Intestinal bile salt transport: structure-activity relationships and other properties

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12 December 2020

Identification of the 14 kDa bile acid transport protein of rat ileal cytosol as gastrotropin

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12 December 2020

Fluorescent bile acid derivatives: Relationship between chemical structure and hepatic and intestinal transport in the rat

1 reference

12 December 2020

Bile acid uptake via the human apical sodium-bile acid cotransporter is electrogenic

1 reference

12 December 2020

Transepithelial transport of cholyltaurine by Caco-2 cell monolayers is sodium dependent

1 reference

12 December 2020