(Q24656252)

2

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Lei Tang

3

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Farit Fazliyez

4

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Lenka Kundrat

5

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George D Markham

6

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Eileen K Jaffe

ALAD porphyria is a conformational disease

7

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language of work or name

English

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publication date

June 2008

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published in

Chemistry and Biology

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volume

15

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issue

6

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page(s)

586-96

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cites work

1 reference

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Rhodobacter capsulatus porphobilinogen synthase, a high activity metal ion independent hexamer

7 April 2017

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Control of tetrapyrrole biosynthesis by alternate quaternary forms of porphobilinogen synthase

7 April 2017

1 reference

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Structure of porphobilinogen synthase from Pseudomonas aeruginosa in complex with 5-fluorolevulinic acid suggests a double Schiff base mechanism

7 April 2017

1 reference

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High resolution crystal structure of a Mg2+-dependent porphobilinogen synthase

7 April 2017

1 reference

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The structure of mouse tumour-necrosis factor at 1.4 A resolution: towards modulation of its selectivity and trimerization

7 April 2017

1 reference

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ON THE NATURE OF ALLOSTERIC TRANSITIONS: A PLAUSIBLE MODEL

7 April 2017

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Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

7 April 2017

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Adapting proteostasis for disease intervention

7 April 2017

1 reference

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Tetrapyrroles: the pigments of life

7 April 2017

1 reference

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Glide: a new approach for rapid, accurate docking and scoring. 2. Enrichment factors in database screening

7 April 2017

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Comparison of Experimental Binding Data and Theoretical Models in Proteins Containing Subunits*

7 April 2017

1 reference

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Inhibiting HIV-1 integrase by shifting its oligomerization equilibrium

7 April 2017

1 reference

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Statistical and conformational analysis of the electron density of protein side chains

28 September 2017

1 reference

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Screening drug-like compounds by docking to homology models: a systematic study.

28 September 2017

1 reference

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Small-molecule inhibition of TNF-alpha

28 September 2017

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Morpheeins--a new structural paradigm for allosteric regulation

28 September 2017

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MollDE: a homology modeling framework you can click with

28 September 2017

1 reference

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Substrate-induced interconversion of protein quaternary structure isoforms

28 September 2017

1 reference

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Searching for new allosteric sites in enzymes

28 September 2017

1 reference

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The porphobilinogen synthase catalyzed reaction mechanism

28 September 2017

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Allosteric proteins and cellular control systems

28 September 2017

1 reference

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Porphobilinogen synthase from pea: expression from an artificial gene, kinetic characterization, and novel implications for subunit interactions.

28 September 2017

1 reference

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Dissociation of enzyme oligomers: a mechanism for allosteric regulation

28 September 2017

1 reference

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Aminolevulinic acid dehydratase in pea (Pisum sativum L.). Identification of an unusual metal-binding domain in the plant enzyme

28 September 2017

1 reference

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Regulatory Mechanisms in Photosynthetic Carbon Metabolism

28 September 2017

1 reference

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A detergent-based assay for the detection of promiscuous inhibitors

28 September 2017

1 reference

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Empirical scoring functions: I. The development of a fast empirical scoring function to estimate the binding affinity of ligands in receptor complexes.

30 May 2018

1 reference

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Single amino acid mutations alter the distribution of human porphobilinogen synthase quaternary structure isoforms (morpheeins).

30 May 2018

1 reference

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Prediction of drug solubility from Monte Carlo simulations.

28 November 2018

1 reference

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An unusual phylogenetic variation in the metal ion binding sites of porphobilinogen synthase

28 November 2018

1 reference

12 December 2020

Conformational diversity and protein evolution--a 60-year-old hypothesis revisited

1 reference

12 December 2020

Synergistic substrate inhibition of ent-copalyl diphosphate synthase: a potential feed-forward inhibition mechanism limiting gibberellin metabolism

1 reference

12 December 2020

Kinetics and thermodynamics of the interchange of the morpheein forms of human porphobilinogen synthase

1 reference

12 December 2020

Characterization of the role of the stimulatory magnesium of Escherichia coli porphobilinogen synthase

1 reference

12 December 2020

5-Aminolevulinic acid dehydratase deficiency porphyria: a twenty-year clinical and biochemical follow-up

1 reference

12 December 2020

The structure of mouse tumour-necrosis factor at 1.4 Å resolution: towards modulation of its selectivity and trimerization

1 reference

Crossref

https://api.crossref.org/works/10.1016%2FJ.CHEMBIOL.2008.04.012

7 January 2021