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Mechanisms of modafinil: A review of current research
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Europe PubMed Central
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2654794
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19300566%20AND%20SRC:MED&resulttype=core&format=json
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24 January 2020
title
Mechanisms of modafinil: A review of current research
(English)
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stated in
Europe PubMed Central
PMCID
2654794
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19300566%20AND%20SRC:MED&resulttype=core&format=json
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24 January 2020
main subject
modafinil
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author
Paul Gerrard
series ordinal
1
1 reference
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Europe PubMed Central
PMCID
2654794
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19300566%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 January 2020
author name string
Robert Malcolm
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2
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Europe PubMed Central
PMCID
2654794
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19300566%20AND%20SRC:MED&resulttype=core&format=json
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24 January 2020
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English
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publication date
1 June 2007
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Europe PubMed Central
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2654794
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24 January 2020
published in
Neuropsychiatric Disease and Treatment
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2654794
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19300566%20AND%20SRC:MED&resulttype=core&format=json
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24 January 2020
volume
3
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Europe PubMed Central
PMCID
2654794
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19300566%20AND%20SRC:MED&resulttype=core&format=json
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24 January 2020
issue
3
1 reference
stated in
Europe PubMed Central
PMCID
2654794
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19300566%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 January 2020
page(s)
349-364
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Europe PubMed Central
PMCID
2654794
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24 January 2020
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Contrasting EEG profiles elicited by antipsychotic agents in the prefrontal cortex of the conscious rat: antagonism of the effects of clozapine by modafinil
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Functional magnetic resonance imaging neuroactivation studies in normal subjects and subjects with the narcoleptic syndrome. Actions of modafinil.
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Brain regional substrates for the actions of the novel wake-promoting agent modafinil in the rat: comparison with amphetamine.
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The vigilance promoting drug modafinil decreases GABA release in the medial preoptic area and in the posterior hypothalamus of the awake rat: possible involvement of the serotonergic 5-HT3 receptor.
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The effects of caffeine, dextroamphetamine, and modafinil on humor appreciation during sleep deprivation.
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Cognitive performance following modafinil versus placebo in sleep-deprived emergency physicians: a double-blind randomized crossover study
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Chronic treatment with modafinil may not be beneficial in patients with chronic fatigue syndrome
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Double-blind, placebo-controlled study of modafinil for fatigue and cognition in schizophrenia patients treated with psychotropic medications.
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Modafinil modulates anterior cingulate function in chronic schizophrenia
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28 November 2018
Does modafinil activate the locus coeruleus in man? Comparison of modafinil and clonidine on arousal and autonomic functions in human volunteers.
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28 November 2018
Endogenous hydrogen peroxide regulates the excitability of midbrain dopamine neurons via ATP-sensitive potassium channels.
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28 November 2018
Dopaminergic-adrenergic interactions in the wake promoting mechanism of modafinil
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28 November 2018
Modafinil enhances the increase of extracellular serotonin levels induced by the antidepressant drugs fluoxetine and imipramine: a dual probe microdialysis study in awake rat.
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28 November 2018
Brain oxidation is an initial process in sleep induction
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28 November 2018
Modafinil more effectively induces wakefulness in orexin-null mice than in wild-type littermates
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28 November 2018
EEG-tomographic studies with LORETA on vigilance differences between narcolepsy patients and controls and subsequent double-blind, placebo-controlled studies with modafinil
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654794
retrieved
28 November 2018
EEG-mapping differences between narcolepsy patients and controls and subsequent double-blind, placebo-controlled studies with modafinil
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654794
retrieved
28 November 2018
Mental effort affects vigilance enduringly: after-effects in EEG and behavior.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654794
retrieved
28 November 2018
Modafinil improves cognition and response inhibition in adult attention-deficit/hyperactivity disorder
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654794
retrieved
28 November 2018
Influence of modafinil on somatosensory input processing in the human brain-stem.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654794
retrieved
28 November 2018
Neuroprotective mechanism of modafinil on Parkinson disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654794
retrieved
28 November 2018
Modafinil: a drug in search of a mechanism.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654794
retrieved
28 November 2018
CYP2C9 gene and susceptibility to major depressive disorder.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654794
retrieved
28 November 2018
When intelligence loses its impact: neural efficiency during reasoning in a familiar area.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654794
retrieved
28 November 2018
Modafinil affects mood, but not cognitive function, in healthy young volunteers
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654794
retrieved
28 November 2018
Distinctive effects of modafinil and d-amphetamine on the homeostatic and circadian modulation of the human waking EEG.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654794
retrieved
28 November 2018
Stress-induced subsensitivity to modafinil and its prevention by corticosteroids
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654794
retrieved
28 November 2018
Toward a quantitative description of large-scale neocortical dynamic function and EEG.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654794
retrieved
28 November 2018
Modafinil does not affect serotonin efflux from rat frontal cortex synaptosomes: comparison with known serotonergic drugs.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654794
retrieved
28 November 2018
The functional anatomy of humor: segregating cognitive and affective components.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654794
retrieved
28 November 2018
State-modulation of cortico-cortical connections underlying normal EEG alpha variants.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654794
retrieved
28 November 2018
A double-blind, placebo-controlled investigation of the efficacy of modafinil for sustaining the alertness and performance of aviators: a helicopter simulator study.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654794
retrieved
28 November 2018
Neuroprotection by ATP-dependent potassium channels in rat neocortical brain slices during hypoxia.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654794
retrieved
28 November 2018
Alpha rhythm emerges from large-scale networks of realistically coupled multicompartmental model cortical neurons.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654794
retrieved
28 November 2018
The vigilance promoting drug modafinil increases extracellular glutamate levels in the medial preoptic area and the posterior hypothalamus of the conscious rat: prevention by local GABAA receptor blockade.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654794
retrieved
28 November 2018
Effects of the vigilance promoting drug modafinil on the synthesis of GABA and glutamate in slices of rat hypothalamus.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654794
retrieved
28 November 2018
Modafinil prevents glutamate cytotoxicity in cultured cortical neurons.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654794
retrieved
28 November 2018
The effects of modafinil on striatal, pallidal and nigral GABA and glutamate release in the conscious rat: evidence for a preferential inhibition of striato-pallidal GABA transmission.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654794
retrieved
28 November 2018
Neural networks for generation and suppression of alpha rhythm: a PET study.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654794
retrieved
28 November 2018
Modafinil: an antinarcoleptic drug with a different neurochemical profile to d-amphetamine and dopamine uptake blockers.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654794
retrieved
28 November 2018
High-resolution EEG mapping of cortical activation related to working memory: effects of task difficulty, type of processing, and practice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654794
retrieved
28 November 2018
Modafinil binds to the dopamine uptake carrier site with low affinity.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654794
retrieved
28 November 2018
Effects of a vigilance-enhancing drug, modafinil, on rat brain metabolism: a 2D COSY 1H-NMR study
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19300566
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Amplification of cortical serotonin release: a further neurochemical action of the vigilance-promoting drug modafinil
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19300566
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Modafinil and cortical gamma-aminobutyric acid outflow. Modulation by 5-hydroxytryptamine neurotoxins
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19300566
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Paradoxical sleep deprivation increases the content of glutamate and glutamine in rat cerebral cortex
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19300566
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Extracellular adenosine levels in neostriatum and hippocampus during rest and activity periods of rats
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19300566
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Antiparkinsonian and neuroprotective effects of modafinil in the mptp-treated common marmoset
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19300566
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Cytochrome P -450 activities in human and rat brain microsomes
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19300566
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
PMCID
2654794
1 reference
stated in
Europe PubMed Central
PMCID
2654794
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19300566%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 January 2020
PubMed ID
19300566
1 reference
stated in
Europe PubMed Central
PMCID
2654794
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19300566%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 January 2020
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