(Q24670063)

2

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K P Wandinger

3

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H F McFarland

4

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R Martin

Journal of Clinical Investigation

5

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language of work or name

English

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publication date

October 2001

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published in

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volume

108

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issue

8

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page(s)

1185-94

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cites work

B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes

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Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

7 April 2017

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T cell receptor (TCR)-mediated repertoire selection and loss of TCR vbeta diversity during the initiation of a CD4(+) T cell response in vivo

7 April 2017

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Clonality and longevity of CD4+CD28null T cells are associated with defects in apoptotic pathways

28 September 2017

1 reference

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CD28 costimulatory blockade exacerbates disease severity and accelerates epitope spreading in a virus-induced autoimmune disease

28 September 2017

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Cbl-b regulates the CD28 dependence of T-cell activation.

28 September 2017

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The B7-CD28/CTLA-4 costimulatory pathways in autoimmune disease of the central nervous system

28 September 2017

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CTLA4Ig-mediated blockade of T-cell costimulation in patients with psoriasis vulgaris

28 September 2017

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Regulation of interleukin (IL)-12 receptor beta2 subunit expression by endogenous IL-12: a critical step in the differentiation of pathogenic autoreactive T cells

28 September 2017

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Resistance to apoptosis and elevated expression of Bcl-2 in clonally expanded CD4+CD28- T cells from rheumatoid arthritis patients

28 September 2017

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Decreased dependence of myelin basic protein-reactive T cells on CD28-mediated costimulation in multiple sclerosis patients. A marker of activated/memory T cells

28 September 2017

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Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) regulates the unfolding of autoimmune diabetes

28 September 2017

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Persistent clonal expansions of peripheral blood CD4+ lymphocytes in chronic inflammatory bowel disease

28 September 2017

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CTLA-4: a negative regulator of autoimmune disease.

28 September 2017

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CD4+ CD7- CD28- T cells are expanded in rheumatoid arthritis and are characterized by autoreactivity

28 September 2017

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Correlation of interleukin-2 and soluble interleukin-2 receptor with clinical activity of multiple sclerosis

28 September 2017

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New perspectives of CD28-B7-mediated T cell costimulation

28 September 2017

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Increased frequency of interleukin 2-responsive T cells specific for myelin basic protein and proteolipid protein in peripheral blood and cerebrospinal fluid of patients with multiple sclerosis

28 September 2017

1 reference

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Immunological aspects of demyelinating diseases

28 September 2017

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Developmental regulation of Lck targeting to the CD8 coreceptor controls signaling in naive and memory T cells

28 September 2017

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T cells responsive to myelin basic protein in patients with multiple sclerosis

30 May 2018

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Paradoxical inhibition of T-cell function in response to CTLA-4 blockade; heterogeneity within the human T-cell population

30 May 2018

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Isolation of self antigen-reactive cells from inflamed islets of nonobese diabetic mice using CD4high expression as a marker.

28 November 2018

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Following the development of a CD4 T cell response in vivo: from activation to memory formation.

28 November 2018

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Blockade of CD28 during in vitro activation of encephalitogenic T cells or after disease onset ameliorates experimental autoimmune encephalomyelitis

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=209525

Costimulatory molecules in Wegener's granulomatosis (WG): lack of expression of CD28 and preferential up-regulation of its ligands B7-1 (CD80) and B7-2 (CD86) on T cells

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=209525

Expansion of autoreactive T cells in multiple sclerosis is independent of exogenous B7 costimulation

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=209525

CTLA-4 blockade enhances clinical disease and cytokine production during experimental allergic encephalomyelitis

28 November 2018

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Intracellular trafficking of CTLA-4 and focal localization towards sites of TCR engagement

28 November 2018

1 reference

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Adhesion molecule expression on cerebrospinal fluid T lymphocytes: evidence for common recruitment mechanisms in multiple sclerosis, aseptic meningitis, and normal controls.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=209525

Transgenic mice that express a myelin basic protein-specific T cell receptor develop spontaneous autoimmunity

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=209525

Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b

28 November 2018

1 reference

12 December 2020

Increased numbers of CCR5+ interferon-gamma- and tumor necrosis factor-alpha-secreting T lymphocytes in multiple sclerosis patients

1 reference

12 December 2020

Human autoreactive CD4+ T cells from naive CD45RA+ and memory CD45RO+ subsets differ with respect to epitope specificity and functional antigen avidity

1 reference

12 December 2020

Encephalitogenic potential of the myelin basic protein peptide (amino acids 83-99) in multiple sclerosis: results of a phase II clinical trial with an altered peptide ligand

1 reference

12 December 2020

T-cell recognition of an immuno-dominant myelin basic protein epitope in multiple sclerosis

1 reference

12 December 2020

Immunology of multiple sclerosis

1 reference

12 December 2020

CD11b+CD28-CD4+ human T cells: activation requirements and association with HLA-DR alleles

1 reference

12 December 2020

1 reference

12 December 2020

1 reference

12 December 2020

T cell growth cytokines cause the superinduction of molecules mediating antigen-induced T lymphocyte death

1 reference

12 December 2020

A very high level of crossreactivity is an essential feature of the T-cell receptor

1 reference

12 December 2020

Identifiers

0 references

1 reference

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PubMed publication ID

11602626

1 reference