(Q24676495)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17227913%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

title

Mechanism of thioamide drug action against tuberculosis and leprosy (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17227913%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

0 references

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17227913%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

Gulcin Gulten

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17227913%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

Lynn Dover

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17227913%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

Gurdyal Besra

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17227913%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

William Jacobs

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17227913%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

author name string

Robert Langley

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17227913%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

James C Sacchettini

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17227913%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

language of work or name

English

0 references

publication date

16 January 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17227913%20AND%20SRC:MED&resulttype=core&format=json

Journal of Experimental Medicine

24 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17227913%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

volume

204

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17227913%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17227913%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

page(s)

73-78

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17227913%20AND%20SRC:MED&resulttype=core&format=json

Mycolic acid synthesis: a target for ethionamide in mycobacteria?

24 December 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118422

Modification of the NADH of the isoniazid target (InhA) from Mycobacterium tuberculosis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118422

Crystal structure and function of the isoniazid target of Mycobacterium tuberculosis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118422

XtalView/Xfit--A versatile program for manipulating atomic coordinates and electron density

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118422

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

7 April 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118422

7 April 2017

https://api.crossref.org/works/10.1084/JEM.20062100

A clinical trial of ethionamide and prothionamide for treatment of lepromatous leprosy

22 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118422

The Prodrug Activator EtaA from Mycobacterium tuberculosis Is a Baeyer-Villiger Monooxygenase

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118422

The antituberculosis drug ethionamide is activated by a flavoprotein monooxygenase

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118422

Ethionamide activation and sensitivity in multidrug-resistant Mycobacterium tuberculosis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118422

Activation of the pro-drug ethionamide is regulated in mycobacteria

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118422

Effect of isoniazid on the in vivo mycolic acid synthesis, cell growth, and viability of Mycobacterium tuberculosis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118422

inhA, a gene encoding a target for isoniazid and ethionamide in Mycobacterium tuberculosis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118422

The catalase-peroxidase gene and isoniazid resistance of Mycobacterium tuberculosis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118422

Emergence of Mycobacterium tuberculosis with extensive resistance to second-line drugs--worldwide, 2000-2004.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118422

Altered NADH/NAD+ ratio mediates coresistance to isoniazid and ethionamide in mycobacteria.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118422

ethA, inhA, and katG loci of ethionamide-resistant clinical Mycobacterium tuberculosis isolates

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118422

Therapeutic implications of inhibition versus killing of Mycobacterium avium complex by antimicrobial agents

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118422

Processing of X-ray diffraction data collected in oscillation mode

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118422

Overexpression of inhA, but not kasA, confers resistance to isoniazid and ethionamide in Mycobacterium smegmatis, M. bovis BCG and M. tuberculosis

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118422

Effects of Ethionamide and Isoxyl on Mycolic Acid Synthesis in Mycobacterium tuberculosis bcg

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118422

Transfer of a point mutation in Mycobacterium tuberculosis inhA resolves the target of isoniazid.

30 May 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20062100

Effect of inhA and katG on isoniazid resistance and virulence of Mycobacterium bovis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20062100

Radical Cyclization of 2-Alkenylthioanilides: A Novel Synthesis of 2,3-Disubstituted Indoles

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20062100

Activity of 16 Antimicrobial Agents Against Drug-Resistant Strains of Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20062100

Treatment of paucibacillary leprosy with a regimen containing rifampicin, dapsone and prothionamide

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17227913

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Action mechanism of antitubercular isoniazid. Activation by Mycobacterium tuberculosis KatG, isolation, and characterization of inha inhibitor

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17227913

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1084/JEM.20062100

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17227913%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17227913%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

1 reference