(Q44198145)

English

Overexpression of inhA, but not kasA, confers resistance to isoniazid and ethionamide in Mycobacterium smegmatis, M. bovis BCG and M. tuberculosis

scientific article published in October 2002

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scholarly article

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Europe PubMed Central

PubMed publication ID

30 November 2017

Overexpression of inhA, but not kasA, confers resistance to isoniazid and ethionamide in Mycobacterium smegmatis, M. bovis BCG and M. tuberculosis (English)

1 reference

Europe PubMed Central

PubMed publication ID

30 November 2017

Mycobacterium tuberculosis

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based on heuristic

inferred from title

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based on heuristic

inferred from title

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based on heuristic

inferred from title

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Mycobacterium smegmatis

object named as

Mycobacterium smegmatis

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based on heuristic

inferred from title

4

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Europe PubMed Central

PubMed publication ID

30 November 2017

3

object named as

Laurent Kremer

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Europe PubMed Central

PubMed publication ID

30 November 2017

author name string

Michelle H Larsen

1

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Europe PubMed Central

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30 November 2017

Catherine Vilchèze

2

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Europe PubMed Central

PubMed publication ID

30 November 2017

Linda Parsons

5

1 reference

Europe PubMed Central

PubMed publication ID

30 November 2017

Max Salfinger

6

1 reference

Europe PubMed Central

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30 November 2017

Leonid Heifets

7

1 reference

Europe PubMed Central

PubMed publication ID

30 November 2017

Manzour H Hazbon

8

1 reference

Europe PubMed Central

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30 November 2017

David Alland

9

1 reference

Europe PubMed Central

PubMed publication ID

30 November 2017

James C Sacchettini

10

1 reference

Europe PubMed Central

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30 November 2017

William R Jacobs

11

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Europe PubMed Central

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30 November 2017

language of work or name

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publication date

1 October 2002

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Europe PubMed Central

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30 November 2017

Molecular Microbiology

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Europe PubMed Central

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30 November 2017

46

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30 November 2017

2

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Europe PubMed Central

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30 November 2017

453-466

1 reference

Europe PubMed Central

PubMed publication ID

30 November 2017

Crystal structure of Mycobacterium tuberculosis 7,8-dihydropteroate synthase in complex with pterin monophosphate: new insight into the enzymatic mechanism and sulfa-drug action

1 reference

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21 January 2018

inhA, a gene encoding a target for isoniazid and ethionamide in Mycobacterium tuberculosis

1 reference

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21 January 2018

The mabA gene from the inhA operon of Mycobacterium tuberculosis encodes a 3-ketoacyl reductase that fails to confer isoniazid resistance

1 reference

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21 January 2018

New horizons in the treatment of tuberculosis

1 reference

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21 January 2018

Mechanisms of isoniazid resistance in Mycobacterium tuberculosis: enzymatic characterization of enoyl reductase mutants identified in isoniazid-resistant clinical isolates.

1 reference

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21 January 2018

Molecular cloning of the gene for dihydrofolate reductase from Lactobacillus casei.

1 reference

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21 January 2018

Ethionamide activation and sensitivity in multidrug-resistant Mycobacterium tuberculosis

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2002.03162.X

21 January 2018

Crystal structure and function of the isoniazid target of Mycobacterium tuberculosis

1 reference

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21 January 2018

Superinfection immunity of mycobacteriophage L5: applications for genetic transformation of mycobacteria

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The chemical approach to the control of tuberculosis

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The Mycobacterium tuberculosis IdeR is a dual functional regulator that controls transcription of genes involved in iron acquisition, iron storage and survival in macrophages

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21 January 2018

Structure and function of the dihydropteroate synthase from Staphylococcus aureus

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21 January 2018

Implications of multidrug resistance for the future of short-course chemotherapy of tuberculosis: a molecular study

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21 January 2018

Genomic mutations in the katG, inhA and aphC genes are useful for the prediction of isoniazid resistance in Mycobacterium tuberculosis isolates from Kwazulu Natal, South Africa.

1 reference

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21 January 2018

Purification and characterization of an unusually large fatty acid synthase from Mycobacterium tuberculosis var. bovis BCG

1 reference

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21 January 2018

Thiolactomycin and related analogues as novel anti-mycobacterial agents targeting KasA and KasB condensing enzymes in Mycobacterium tuberculosis

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2002.03162.X

21 January 2018

Novel mutations in ndh in isoniazid-resistant Mycobacterium tuberculosis isolates

1 reference

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21 January 2018

Three-dimensional structure of M. tuberculosis dihydrofolate reductase reveals opportunities for the design of novel tuberculosis drugs

1 reference

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21 January 2018

Differential expression of 10 sigma factor genes in Mycobacterium tuberculosis

1 reference

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21 January 2018

Biochemical and genetic data suggest that InhA is not the primary target for activated isoniazid in Mycobacterium tuberculosis

1 reference

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21 January 2018

Inhibition of a Mycobacterium tuberculosis beta-ketoacyl ACP synthase by isoniazid.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2002.03162.X

21 January 2018

Plasmid-mediated sulfanilamide resistance.

1 reference

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21 January 2018

Genotypic analysis of Mycobacterium tuberculosis in two distinct populations using molecular beacons: implications for rapid susceptibility testing

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21 January 2018

Enzymatic characterization of the target for isoniazid in Mycobacterium tuberculosis

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21 January 2018

New isoniazid/ethionamide resistance gene mutation and screening for multidrug-resistant Mycobacterium tuberculosis strains.

1 reference

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21 January 2018

Escherichia coli as a model for the regulation of dissociable (type II) fatty acid biosynthesis

1 reference

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21 January 2018

Characterization of the katG and inhA genes of isoniazid-resistant clinical isolates of Mycobacterium tuberculosis

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2002.03162.X

21 January 2018

Modification of the NADH of the isoniazid target (InhA) from Mycobacterium tuberculosis

1 reference

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21 January 2018

Gene amplification and drug resistance in cultured murine cells.

1 reference

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21 January 2018

R-factor-mediated resistance to sulfonamides by a plasmid-borne, drug-resistant dihydropteroate synthase

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2002.03162.X

21 January 2018

The genetics and biochemistry of isoniazid resistance in mycobacterium tuberculosis.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2002.03162.X

21 January 2018

Isoniazid affects multiple components of the type II fatty acid synthase system of Mycobacterium tuberculosis.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2002.03162.X

21 January 2018

Lysogeny and transformation in mycobacteria: stable expression of foreign genes

1 reference

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21 January 2018

Isolation and characterization of efficient plasmid transformation mutants of Mycobacterium smegmatis

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21 January 2018

New use of BCG for recombinant vaccines

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Effect of isoniazid on the in vivo mycolic acid synthesis, cell growth, and viability of Mycobacterium tuberculosis

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Inactivation of the inhA-encoded fatty acid synthase II (FASII) enoyl-acyl carrier protein reductase induces accumulation of the FASI end products and cell lysis of Mycobacterium smegmatis

1 reference

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21 January 2018

Effect of inhA and katG on isoniazid resistance and virulence of Mycobacterium bovis.

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Exploring drug-induced alterations in gene expression in Mycobacterium tuberculosis by microarray hybridization

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Inhibition by Isoniazid of Synthesis of Mycolic Acids in Mycobacterium tuberculosis

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Sulfonamide resistance mechanism in Escherichia coli: R plasmids can determine sulfonamide-resistant dihydropteroate synthases

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21 January 2018

The catalase-peroxidase gene and isoniazid resistance of Mycobacterium tuberculosis

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Transformation with katG restores isoniazid-sensitivity in Mycobacterium tuberculosis isolates resistant to a range of drug concentrations

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Evaluation of inhA gene and catalase-peroxidase gene among isoniazid-sensitive and resistantMycobacterium tuberculosisisolates

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21 January 2018

Identifiers

10.1046/J.1365-2958.2002.03162.X

1 reference

Europe PubMed Central

PubMed publication ID

30 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 November 2017

ResearchGate publication ID

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