(Q43509450)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11069675%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

title

Isoniazid affects multiple components of the type II fatty acid synthase system of Mycobacterium tuberculosis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11069675%20AND%20SRC:MED&resulttype=core&format=json

Mycobacterium tuberculosis

1 November 2019

main subject

fatty acid

0 references

0 references

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11069675%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Richard Lee

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11069675%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Clifton E Barry

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11069675%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

author name string

R E Lee

2

1 reference

24 November 2017

C E Barry

3

1 reference

24 November 2017

language of work or name

English

0 references

publication date

1 November 2000

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11069675%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

published in

Molecular Microbiology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11069675%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

volume

38

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11069675%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11069675%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

page(s)

514-525

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11069675%20AND%20SRC:MED&resulttype=core&format=json

inhA, a gene encoding a target for isoniazid and ethionamide in Mycobacterium tuberculosis

1 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2000.02145.X

Mycolic acids: structure, biosynthesis and physiological functions

21 January 2018

1 reference

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Treatment of tuberculosis and tuberculosis infection in adults and children. American Thoracic Society and The Centers for Disease Control and Prevention

21 January 2018

1 reference

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Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence

21 January 2018

1 reference

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The salicylate-derived mycobactin siderophores of Mycobacterium tuberculosis are essential for growth in macrophages

21 January 2018

1 reference

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Mycobacterium tuberculosis is a natural mutant with an inactivated oxidative-stress regulatory gene: implications for sensitivity to isoniazid

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2000.02145.X

The extreme sensitivity of Mycobacterium tuberculosis to the front-line antituberculosis drug isoniazid

21 January 2018

1 reference

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The biosynthesis of cyclopropanated mycolic acids in Mycobacterium tuberculosis. Identification and functional analysis of CMAS-2

21 January 2018

1 reference

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Implications of multidrug resistance for the future of short-course chemotherapy of tuberculosis: a molecular study

21 January 2018

1 reference

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Thiolactomycin and related analogues as novel anti-mycobacterial agents targeting KasA and KasB condensing enzymes in Mycobacterium tuberculosis

21 January 2018

1 reference

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Molecular basis of triclosan activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2000.02145.X

A mutant of Mycobacterium smegmatis defective in the biosynthesis of mycolic acids accumulates meromycolates

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2000.02145.X

Triclosan targets lipid synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2000.02145.X

InhA, a target of the antituberculous drug isoniazid, is involved in a mycobacterial fatty acid elongation system, FAS-II

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2000.02145.X

Biochemical and genetic data suggest that InhA is not the primary target for activated isoniazid in Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2000.02145.X

Inhibition of a Mycobacterium tuberculosis beta-ketoacyl ACP synthase by isoniazid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2000.02145.X

Mechanisms involved in the intrinsic isoniazid resistance of Mycobacterium avium

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2000.02145.X

Characterization of the catalase-peroxidase gene (katG) and inhA locus in isoniazid-resistant and -susceptible strains of Mycobacterium tuberculosis by automated DNA sequencing: restricted array of mutations associated with drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2000.02145.X

Inhibition of InhA, the enoyl reductase from Mycobacterium tuberculosis, by triclosan and isoniazid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2000.02145.X

Genotypic analysis of Mycobacterium tuberculosis in two distinct populations using molecular beacons: implications for rapid susceptibility testing

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2000.02145.X

Characterization of the katG and inhA genes of isoniazid-resistant clinical isolates of Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2000.02145.X

Modification of the NADH of the isoniazid target (InhA) from Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2000.02145.X

Disparate responses to oxidative stress in saprophytic and pathogenic mycobacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2000.02145.X

Compensatory ahpC gene expression in isoniazid-resistant Mycobacterium tuberculosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2000.02145.X

Restricted structural gene polymorphism in the Mycobacterium tuberculosis complex indicates evolutionarily recent global dissemination

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2000.02145.X

Structural basis and mechanism of enoyl reductase inhibition by triclosan

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2000.02145.X

Kinetic and structural characteristics of the inhibition of enoyl (acyl carrier protein) reductase by triclosan

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2000.02145.X

Exploring drug-induced alterations in gene expression in Mycobacterium tuberculosis by microarray hybridization

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2000.02145.X

The catalase-peroxidase gene and isoniazid resistance of Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.2000.02145.X