Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q24676606)
Watch
English
Transgenic models of Huntington's disease
scientific article
In more languages
edit
Statements
instance of
scholarly article
0 references
review article
1 reference
stated in
Europe PubMed Central
title
Transgenic models of Huntington's disease
(English)
0 references
main subject
Huntington's disease
0 references
author name string
K Sathasivam
series ordinal
1
0 references
C Hobbs
series ordinal
2
0 references
L Mangiarini
series ordinal
3
0 references
A Mahal
series ordinal
4
0 references
M Turmaine
series ordinal
5
0 references
P Doherty
series ordinal
6
0 references
S W Davies
series ordinal
7
0 references
G P Bates
series ordinal
8
0 references
language of work or name
English
0 references
publication date
29 June 1999
0 references
published in
Philosophical Transactions of the Royal Society B
0 references
volume
354
0 references
issue
1386
0 references
page(s)
963-9
0 references
cites work
Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692600
retrieved
7 April 2017
Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692600
retrieved
7 April 2017
Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692600
retrieved
7 April 2017
Cellular localization of the Huntington's disease protein and discrimination of the normal and mutated form
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692600
retrieved
7 April 2017
Inactivation of the mouse Huntington's disease gene homolog Hdh
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692600
retrieved
7 April 2017
Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692600
retrieved
7 April 2017
Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692600
retrieved
7 April 2017
Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692600
retrieved
7 April 2017
Nonneural nuclear inclusions of androgen receptor protein in spinal and bulbar muscular atrophy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692600
retrieved
28 September 2017
Altered brain neurotransmitter receptors in transgenic mice expressing a portion of an abnormal human huntington disease gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692600
retrieved
28 September 2017
Subcellular localization of the Huntington's disease gene product in cell lines by immunofluorescence and biochemical subcellular fractionation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692600
retrieved
28 September 2017
Phenotypic characterization of individuals with 30-40 CAG repeats in the Huntington disease (HD) gene reveals HD cases with 36 repeats and apparently normal elderly individuals with 36-39 repeats
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692600
retrieved
28 September 2017
Correlation between the onset age of Huntington's disease and length of the trinucleotide repeat in IT-15.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692600
retrieved
28 September 2017
Glutamine repeats as polar zippers: their possible role in inherited neurodegenerative diseases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692600
retrieved
28 September 2017
Structure and expression of the Huntington's disease gene: evidence against simple inactivation due to an expanded CAG repeat
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692600
retrieved
28 September 2017
Identification and localization of huntingtin in brain and human lymphoblastoid cell lines with anti-fusion protein antibodies
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692600
retrieved
28 September 2017
When more is less: pathogenesis of glutamine repeat neurodegenerative diseases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692600
retrieved
28 September 2017
Inverse relationship between age at onset of Huntington disease and paternal age suggests involvement of genetic imprinting
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692600
retrieved
28 September 2017
Intranuclear neuronal inclusions in Huntington's disease and dentatorubral and pallidoluysian atrophy: correlation between the density of inclusions and IT15 CAG triplet repeat length
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692600
retrieved
30 May 2018
Structural neurology: are seeds at the root of neuronal degeneration?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692600
retrieved
30 May 2018
Widespread expression of Huntington's disease gene (IT15) protein product
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692600
retrieved
30 May 2018
Body weight and dietary factors in Huntington's disease patients compared with matched controls
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692600
retrieved
30 May 2018
Morphometric demonstration of atrophic changes in the cerebral cortex, white matter, and neostriatum in Huntington's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692600
retrieved
30 May 2018
Neuropathological classification of Huntington's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692600
retrieved
30 May 2018
Decreased neuronal and increased oligodendroglial densities in Huntington's disease caudate nucleus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692600
retrieved
30 May 2018
Transgenic mice in the study of polyglutamine repeat expansion diseases.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692600
retrieved
28 November 2018
Ectopically expressed CAG repeats cause intranuclear inclusions and a progressive late onset neurological phenotype in the mouse.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692600
retrieved
28 November 2018
Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692600
retrieved
28 November 2018
Identification of an HD patient with a (CAG)180 repeat expansion and the propagation of highly expanded CAG repeats in lambda phage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692600
retrieved
28 November 2018
Instability of highly expanded CAG repeats in mice transgenic for the Huntington's disease mutation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692600
retrieved
28 November 2018
Comparative sequence analysis of the human and pufferfish Huntington's disease genes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1098%2FRSTB.1999.0447
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Self-assembly of polyglutamine-containing huntingtin fragments into amyloid-like fibrils: implications for Huntington's disease pathology
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1098%2FRSTB.1999.0447
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Formation of polyglutamine inclusions in non-CNS tissue
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1098%2FRSTB.1999.0447
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of progressive motor deficits in mice transgenic for the human Huntington's disease mutation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1098%2FRSTB.1999.0447
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1098/RSTB.1999.0447
0 references
PMC publication ID
1692600
0 references
PubMed publication ID
10434294
0 references
ResearchGate publication ID
12866068
0 references
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit
