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Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue
scientific journal article
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scholarly article
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stated in
PubMed
PubMed ID
7550343
retrieved
24 January 2017
title
Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue
(English)
1 reference
stated in
PubMed
PubMed ID
7550343
retrieved
24 January 2017
main subject
apoptotic process
0 references
Huntington's disease
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Huntingtin
1 reference
stated in
GOA release 2020-03-11
author
Virginia E Papaioannou
object named as
V. E. Papaioannou
series ordinal
4
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author name string
S. Zeitlin
series ordinal
1
1 reference
stated in
PubMed
PubMed ID
7550343
retrieved
24 January 2017
J. P. Liu
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
7550343
retrieved
24 January 2017
D. L. Chapman
series ordinal
3
1 reference
stated in
PubMed
PubMed ID
7550343
retrieved
24 January 2017
A. Efstratiadis
series ordinal
5
1 reference
stated in
PubMed
PubMed ID
7550343
retrieved
24 January 2017
language of work or name
English
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publication date
1 October 1995
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stated in
PubMed
PubMed ID
7550343
retrieved
24 January 2017
published in
Nature Genetics
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stated in
PubMed
PubMed ID
7550343
retrieved
24 January 2017
volume
11
1 reference
stated in
PubMed
PubMed ID
7550343
retrieved
24 January 2017
page(s)
155–163
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stated in
PubMed
PubMed ID
7550343
retrieved
24 January 2017
issue
2
1 reference
stated in
PubMed
PubMed ID
7550343
retrieved
24 January 2017
exact match
https://scigraph.springernature.com/pub.10.1038/ng1095-155
0 references
cites work
Cellular localization of the Huntington's disease protein and discrimination of the normal and mutated form
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038/NG1095-155
retrieved
21 April 2017
Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038/NG1095-155
retrieved
21 April 2017
Cell death in health and disease: the biology and regulation of apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038/NG1095-155
retrieved
21 April 2017
Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038/NG1095-155
retrieved
21 April 2017
Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1095-155
retrieved
21 April 2017
Genetics and molecular biology of Huntington's disease
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1095-155
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Huntington's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1095-155
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The functional anatomy of basal ganglia disorders
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1095-155
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for apoptotic cell death in Huntington disease and excitotoxic animal models.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1095-155
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA end labeling (TUNEL) in Huntington's disease and other neuropathological conditions
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1095-155
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1095-155
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure and expression of the Huntington's disease gene: evidence against simple inactivation due to an expanded CAG repeat
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1095-155
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dynamic mutations: a new class of mutations causing human disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1095-155
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dynamic mutations on the move
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1095-155
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Widespread expression of Huntington's disease gene (IT15) protein product
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1095-155
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1095-155
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence from antibody studies that the CAG repeat in the Huntington disease gene is expressed in the protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1095-155
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A worldwide study of the Huntington's disease mutation. The sensitivity and specificity of measuring CAG repeats
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1095-155
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Trinucleotide repeat length instability and age of onset in Huntington's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1095-155
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular analysis of juvenile Huntington disease: the major influence on (CAG)n repeat length is the sex of the affected parent.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1095-155
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Correlation between the onset age of Huntington's disease and length of the trinucleotide repeat in IT-15.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1095-155
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A CCG repeat polymorphism adjacent to the CAG repeat in the Huntington disease gene: implications for diagnostic accuracy and predictive testing
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1095-155
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A single allele from the polymorphic CCG rich sequence immediately 3' to the unstable CAG trinucleotide in the IT15 cDNA shows almost complete disequilibrium with Huntington's disease chromosomes in the Scottish population
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1095-155
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Huntington's disease gene (IT15) is widely expressed in human and rat tissues
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1095-155
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Widespread expression of the human and rat Huntington's disease gene in brain and nonneural tissues
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1095-155
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization and localization of the Huntington disease gene product
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1095-155
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Huntington's disease gene: regional and cellular expression in brain of normal and affected individuals
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1095-155
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcriptional activation modulated by homopolymeric glutamine and proline stretches
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1095-155
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mouse Huntington's disease gene homolog (Hdh).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1095-155
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1095-155
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inactivation of the mouse Huntington's disease gene homolog Hdh
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1095-155
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of apoptosis in early mouse embryos by 2'-deoxyadenosine exposure
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1095-155
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Development, morphology, and function of the yolk-sac placenta of laboratory rodents
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1095-155
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell lineage analysis of the primitive and visceral endoderm of mouse embryos cultured in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1095-155
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Disruption of the HNF-4 gene, expressed in visceral endoderm, leads to cell death in embryonic ectoderm and impaired gastrulation of mouse embryos
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1095-155
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Death before birth: clues from gene knockouts and mutations
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1095-155
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
fgfr-1 is required for embryonic growth and mesodermal patterning during mouse gastrulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1095-155
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Murine FGFR-1 is required for early postimplantation growth and axial organization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1095-155
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted disruption of the even-skipped gene, evx1, causes early postimplantation lethality of the mouse conceptus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1095-155
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dicing with death: dissecting the components of the apoptosis machinery.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1095-155
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Is compensatory growth a complicating factor in mouse teratology?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1095-155
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Growth and its control in early mammalian development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1095-155
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Social controls on cell survival and cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1095-155
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations associated with amyotrophic lateral sclerosis convert superoxide dismutase from an antiapoptotic gene to a proapoptotic gene: studies in yeast and neural cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1095-155
retrieved
7 January 2021
based on heuristic
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A method to isolate DNA from small archival tissue samples for p53 gene analysis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1095-155
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/NG1095-155
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1481991
Dimensions Publication ID
1035910928
0 references
OpenCitations bibliographic resource ID
1481991
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1481991
PubMed ID
7550343
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1481991
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