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Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development
scientific journal article
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scholarly article
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PubMed
PubMed ID
2202907
retrieved
31 January 2017
title
Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development
(English)
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PubMed
PubMed ID
2202907
retrieved
31 January 2017
main subject
brain
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cerebellum
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Wingless-type MMTV integration site family, member 1
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GOA release 2020-03-11
author name string
K. R. Thomas
series ordinal
1
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PubMed
PubMed ID
2202907
retrieved
31 January 2017
M. R. Capecchi
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
2202907
retrieved
31 January 2017
language of work or name
English
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publication date
30 August 1990
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PubMed
PubMed ID
2202907
retrieved
31 January 2017
published in
Nature
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stated in
PubMed
PubMed ID
2202907
retrieved
31 January 2017
volume
346
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stated in
PubMed
PubMed ID
2202907
retrieved
31 January 2017
issue
6287
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stated in
PubMed
PubMed ID
2202907
retrieved
31 January 2017
page(s)
847–850
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PubMed
PubMed ID
2202907
retrieved
31 January 2017
cites work
Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2F346847A0
retrieved
7 January 2021
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Structure and nucleotide sequence of the putative mammary oncogene int-1; proviral insertions leave the protein-encoding domain intact.
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F346847A0
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7 January 2021
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inferred from DOI database lookup
Two proto-oncogenes implicated in mammary carcinogenesis, int-1 and int-2, are independently regulated during mouse development
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F346847A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of the proto-oncogene int-1 is restricted to postmeiotic male germ cells and the neural tube of mid-gestational embryos.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F346847A0
retrieved
7 January 2021
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Expression of the proto-oncogene int-1 is restricted to specific neural cells in the developing mouse embryo
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F346847A0
retrieved
7 January 2021
based on heuristic
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The Drosophila homolog of the mouse mammary oncogene int-1 is identical to the segment polarity gene wingless
1 reference
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https://api.crossref.org/works/10.1038%2F346847A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The development of wingless, a homeotic mutation of Drosophila
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F346847A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular cloning of sequences from wingless, a segment polarity gene in Drosophila: the spatial distribution of a transcript in embryos.
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F346847A0
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7 January 2021
based on heuristic
inferred from DOI database lookup
The int-1 proto-oncogene products are glycoproteins that appear to enter the secretory pathway
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F346847A0
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7 January 2021
based on heuristic
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Secreted int-1 protein is associated with the cell surface
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F346847A0
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7 January 2021
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inferred from DOI database lookup
Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F346847A0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2F346847A0
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7 January 2021
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inferred from DOI database lookup
The new mouse genetics: altering the genome by gene targeting
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F346847A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Altering the genome by homologous recombination
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F346847A0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Towards a molecular-genetic analysis of mammalian development
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F346847A0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F346847A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted mutation of the Hprt gene in mouse embryonic stem cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F346847A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Production of chimaeric mice containing embryonic stem (ES) cells carrying a homoeobox Hox 1.1 allele mutated by homologous recombination.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F346847A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Production of a mutation in mouse En-2 gene by homologous recombination in embryonic stem cells.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F346847A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeting of nonexpressed genes in embryonic stem cells via homologous recombination
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F346847A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inactivating the beta 2-microglobulin locus in mouse embryonic stem cells by homologous recombination
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F346847A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Germ-line transmission of a disrupted beta 2-microglobulin gene produced by homologous recombination in embryonic stem cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F346847A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Germ-line transmission of a c-abl mutation produced by targeted gene disruption in ES cells.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F346847A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Beta 2-microglobulin deficient mice lack CD4-8+ cytolytic T cells.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F346847A0
retrieved
7 January 2021
based on heuristic
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A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F346847A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Normal development of mice deficient in beta 2M, MHC class I proteins, and CD8+ T cells.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F346847A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Homologous recombination in hybridoma cells: heavy chain chimeric antibody produced by gene targeting
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F346847A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted gene disruption of the endogenous c-abl locus by homologous recombination with DNA encoding a selectable fusion protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F346847A0
retrieved
7 January 2021
based on heuristic
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Identifiers
DOI
10.1038/346847A0
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3092075
Dimensions Publication ID
1027532470
0 references
OpenCitations bibliographic resource ID
3092075
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3092075
PubMed ID
2202907
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3092075
ResearchGate publication ID
20952966
0 references
Springer Nature article ID
10.1038/346847a0
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