(Q24680363)

24 June 2017

title

MDL 26,479: a potential cognition enhancer with benzodiazepine inverse agonist-like properties (English)

1 reference

24 June 2017

J A Miller

1

1 reference

24 June 2017

M W Dudley

2

1 reference

24 June 2017

J H Kehne

3

1 reference

24 June 2017

S M Sorensen

4

1 reference

24 June 2017

J M Kane

5

1 reference

24 June 2017

language of work or name

English

0 references

publication date

1 September 1992

1 reference

British Journal of Pharmacology

24 June 2017

published in

1 reference

24 June 2017

volume

107

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24 June 2017

issue

1

1 reference

24 June 2017

page(s)

78-86

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Protein measurement with the Folin phenol reagent

24 June 2017

cites work

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Long-lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path

7 April 2017

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Effects of anticonvulsants in vivo on high affinity choline uptake in vitro in mouse hippocampal synaptosomes

7 April 2017

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Effect of the 'antidementia drug' pantoyl-GABA on high affinity transport of choline and on the contents of choline and acetylcholine in rat brain

7 April 2017

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Pharmacological characterization of benzodiazepine receptors in the brain

7 April 2017

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Benzodiazepine impairs and beta-carboline enhances performance in learning and memory tasks

7 April 2017

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Effect of scopolamine and HP 029, a cholinesterase inhibitor, on long-term potentiation in hippocampal slices of the guinea pig.

28 September 2017

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Treatment strategies for senile dementia: antagonist beta-carbolines

28 September 2017

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Activating the damaged basal forebrain cholinergic system: tonic stimulation versus signal amplification

28 September 2017

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Neurotransmitter-related enzymes and indices of hypoxia in senile dementia and other abiotrophies

28 September 2017

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High-affinity choline uptake in the hippocampus: its relationship to the physiological state produced by administration of barbiturates and other treatments.

28 September 2017

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The action of piracetam on the electrical activity of the hippocampal slice preparation: a field potential analysis.

30 May 2018

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Loss of neurons in the nucleus basalis of Meynert in Alzheimer's disease, paralysis agitans and Korsakoff's Disease

30 May 2018

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A benzodiazepine receptor-mediated model of anxiety. Studies in nonhuman primates and clinical implications.

30 May 2018

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Interactions of ethyl-β-carboline-3-carboxylate and Ro 15-1788 with CGS 8216 in an animal model of anxiety

30 May 2018

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Binding of [3H]DMCM, a convulsive benzodiazepine ligand, to rat brain membranes: preliminary studies.

30 May 2018

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Pharmacological manipulations of the substantia innominata-cortical cholinergic pathway

30 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1907590

Absence of intrinsic antagonist actions of benzodiazepine antagonists on an exploratory model of anxiety in the mouse

30 May 2018

1 reference

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Medial septal facilitation of hippocampal granule cell activity is mediated by inhibition of inhibitory interneurones.

30 May 2018

1 reference

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Central noradrenergic involvement in yohimbine excitation of acoustic startle: effects of DSP4 and 6-OHDA.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1907590

Effects of GABAergic drugs in vivo on high-affinity choline uptake in vitro in mouse hippocampal synaptosomes.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1907590

Effect of oxiracetam and piracetam on central cholinergic mechanisms and active-avoidance acquisition.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1907590

An improved calibration procedure for computer-based quantitative autoradiography utilizing a mathematical model for the non-linear response of camera and film

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1907590

Induction of cortical cholinergic hypofunction and memory retention deficits through intracortical AF64A infusions

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1907590

Rearing paradigm in a nonhuman primate affects response to beta-CCE challenge.

30 May 2018

1 reference

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A simple and rapid method of inducing physical dependence with benzodiazepines in mice

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1907590

The effects of various cognition-enhancing drugs on in vitro rat hippocampal synaptosomal sodium dependent high affinity choline uptake.

30 May 2018

1 reference

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Neuropharmacological antagonism of the beta-carboline-induced "anxiety" response in rhesus monkeys.

30 May 2018

1 reference

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Continuous slow release of low levels of diazepam produces tolerance to its depressant and anxiolytic effects on the startle reflex.

30 May 2018

1 reference

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'GABA shift' in vivo: enhancement of benzodiazepine binding in vivo by modulation of endogenous GABA.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1907590

Attenuation of scopolamine-induced impairment of spontaneous alteration behaviour by antagonist but not inverse agonist and agonist beta-carbolines

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1907590

Spontaneous exploration of a 6-arm radial tunnel maze by basal forebrain lesioned rats: effects of the benzodiazepine receptor antagonist beta-carboline ZK 93 426.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1907590

Stress-induced changes in t-[35S]butylbicyclophosphorothionate binding to gamma-aminobutyric acid-gated chloride channels are mimicked by in vitro occupation of benzodiazepine receptors.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1907590

Rat pup ultrasonic isolation calls: possible mediation by the benzodiazepine receptor complex.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1907590

The effects of a potential antidepressant, 2,4-dimethyl-5-(3-fluorophenyl)-3H-1,2,4-triazole-3-thione, in an electrophysiological model responsive to desipramine

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1907590

Effect of the nootropic drug oxiracetam on field potentials of rat hippocampal slices

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1907590

High affinity [3H]glibenclamide binding sites in rat neuronal and cardiac tissue: localization and developmental characteristics.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1907590

NMDA receptor complex antagonists have potential anxiolytic effects as measured with separation-induced ultrasonic vocalizations

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1907590

Enhancement of working memory performance in the rat by MDL 26,479, a novel compound with activity at the GABAA receptor complex.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1907590

Sodium-dependent high affinity choline uptake: a regulatory step in the synthesis of acetylcholine

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1907590

[3H](-)Baclofen: an improved ligand for GABAB sites

30 May 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.1992.TB14466.X

Benzodiazepine receptor ligands with positive and negative efficacy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.1992.TB14466.X

The anxiogenic action of benzodiazepine antagonists.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.1992.TB14466.X

The regulation of high-affinity choline uptake in vitro in rat cortical and hippocampal synaptosomes by beta-carbolines administered in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.1992.TB14466.X

Choline uptake and permanent memory storage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.1992.TB14466.X

Presynaptic cholinergic mechanisms in brain of aged rats with memory impairments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.1992.TB14466.X

Differential hippocampal and cortical cholinergic activation during the acquisition, retention, reversal and extinction of a spatial discrimination in an 8-arm radial maze by mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.1992.TB14466.X

Behavioral and physiological responses to benzodiazepine receptor antagonists.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1907590

Physostigmine induces in rats a phenomenon resembling long-term potentiation

28 November 2018

1 reference

12 December 2020

2,4-Dihydro-3H-1,2,4-triazole-3-thiones as potential antidepressant agents

1 reference

12 December 2020

Noradrenergic responses in rat hippocampus: Evidence for mediation by α and β receptors in the in vitro slice

1 reference

12 December 2020

Na+-independent binding of [3H]GABA and [3H]muscimol to subcellular particles of neural primary cultures and whole brain

1 reference

12 December 2020

Effects of the serotonin releasers 3,4-methylenedioxymethamphetamine (MDMA), 4-chloroamphetamine (PCA) and fenfluramine on acoustic and tactile startle reflexes in rats

1 reference

12 December 2020

Distress vocalization in rat pups. A simple screening method for anxiolytic drugs

1 reference

12 December 2020

Oxygen desaturation during ventilator circuit changes

1 reference

12 December 2020

Binding of [3H]3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid to rat brain membranes: a selective, high-affinity ligand for N-methyl-D-aspartate receptors

1 reference

12 December 2020

10.1111/J.1476-5381.1992.TB14466.X

Identifiers

DOI

1 reference

24 June 2017

0 references

1 reference