(Q24682717)

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Genetic analysis of the calcineurin pathway identifies members of the EGR gene family, specifically EGR3, as potential susceptibility candidates in schizophrenia

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Genetic analysis of the calcineurin pathway identifies members of the EGR gene family, specifically EGR3, as potential susceptibility candidates in schizophrenia (English)

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Susumu Tonegawa

9

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object named as

Jun Aruga

7

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Yoshimi Iwayama

3

object named as

Yoshimi Iwayama

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1

object named as

Kazuo Yamada

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author name string

David J Gerber

2

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Tetsuo Ohnishi

4

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Hisako Ohba

5

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Tomoko Toyota

6

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Yoshio Minabe

8

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Takeo Yoshikawa

10

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language of work or name

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publication date

20 February 2007

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Proceedings of the National Academy of Sciences of the United States of America

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104

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8

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2815-20

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T cell deficiency leads to cognitive dysfunction: implications for therapeutic vaccination for schizophrenia and other psychiatric conditions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1815264

7 April 2017

Evidence for association of schizophrenia with genetic variation in the 8p21.3 gene, PPP3CC, encoding the calcineurin gamma subunit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1815264

7 April 2017

Conditional calcineurin knockout mice exhibit multiple abnormal behaviors related to schizophrenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1815264

7 April 2017

Neuregulin 1 and susceptibility to schizophrenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1815264

7 April 2017

Inference of population structure using multilocus genotype data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1815264

7 April 2017

Enhancement of D1 dopamine receptor-mediated locomotor stimulation in M(4) muscarinic acetylcholine receptor knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1815264

7 April 2017

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1815264

7 April 2017

Sensory ataxia and muscle spindle agenesis in mice lacking the transcription factor Egr3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1815264

7 April 2017

PedCheck: a program for identification of genotype incompatibilities in linkage analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1815264

7 April 2017

Muscarinic acetylcholine receptors activate expression of the EGR gene family of transcription factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1815264

7 April 2017

Mutations in the early growth response 2 (EGR2) gene are associated with hereditary myelinopathies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1815264

7 April 2017

Identification of multiple serine racemase (SRR) mRNA isoforms and genetic analyses of SRR and DAO in schizophrenia and D-serine levels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1815264

7 April 2017

Neuregulin 1-erbB signaling and the molecular/cellular basis of schizophrenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1815264

7 April 2017

Axonal neuregulin-1 regulates myelin sheath thickness

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1815264

7 April 2017

Signal transduction and genes-to-behaviors pathways in psychiatric diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1815264

7 April 2017

Activated glycogen synthase-3 beta suppresses cardiac hypertrophy in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1815264

7 April 2017

Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1815264

7 April 2017

Luteinizing hormone deficiency and female infertility in mice lacking the transcription factor NGFI-A (Egr-1)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1815264

7 April 2017

Hyperactivity, elevated dopaminergic transmission, and response to amphetamine in M1 muscarinic acetylcholine receptor-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1815264

7 April 2017

An update on the genetics of schizophrenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1815264

28 September 2017

Prefrontal functioning during context processing in schizophrenia and major depression: an event-related fMRI study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1815264

28 September 2017

Cortical cholinergic transmission and cortical information processing in schizophrenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1815264

28 September 2017

Egr-2 and Egr-3 are negative regulators of T cell activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1815264

28 September 2017

Decreased hippocampal expression of the susceptibility gene PPP3CC and other calcineurin subunits in schizophrenia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1815264

28 September 2017

Neuregulin induces the expression of transcription factors and myosin heavy chains typical of muscle spindles in cultured human muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1815264

28 September 2017

The genetics of schizophrenia: glutamate not dopamine?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1815264

28 September 2017

Calcineurin regulation of neuronal plasticity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1815264

28 September 2017

Methylation at CpG islands in intron 1 of EGR2 confers enhancer-like activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1815264

28 September 2017

White matter changes in schizophrenia: evidence for myelin-related dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1815264

28 September 2017

T cell apoptosis and reactive oxygen species

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1815264

28 September 2017

Decreased muscarinic1 receptors in the dorsolateral prefrontal cortex of subjects with schizophrenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1815264

28 September 2017

Calcineurin as a multifunctional regulator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1815264

28 September 2017

Roles of serine/threonine phosphatases in hippocampal synaptic plasticity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1815264

28 September 2017

Genome-wide expression analysis reveals dysregulation of myelination-related genes in chronic schizophrenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1815264

28 September 2017

Functional comparison of Egr3 transcription factor isoforms: identification of an activation domain in the N-terminal segment absent from Egr3beta, a major isoform expressed in brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1815264

28 September 2017

A test for linkage and association in general pedigrees: the pedigree disequilibrium test

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1815264

28 September 2017

The EGR family of transcription-regulatory factors: progress at the interface of molecular and systems neuroscience.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1815264

28 September 2017

The early growth response protein (EGR-1) regulates interleukin-2 transcription by synergistic interaction with the nuclear factor of activated T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1815264

28 September 2017

Convergent evidence for impaired AKT1-GSK3beta signaling in schizophrenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1815264

30 May 2018

Forebrain-specific calcineurin knockout selectively impairs bidirectional synaptic plasticity and working/episodic-like memory

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0610765104

21 January 2018

Distinguishable haplotype blocks in the HTR3A and HTR3B region in the Japanese reveal evidence of association of HTR3B with female major depression

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0610765104

21 January 2018

The transcription factor Egr3 modulates sensory axon-myotube interactions during muscle spindle morphogenesis.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0610765104

21 January 2018

Decreased density of muscarinic receptors in the superior temporal gyrusin schizophrenia

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0610765104

21 January 2018

In vivo determination of muscarinic acetylcholine receptor availability in schizophrenia

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0610765104

21 January 2018

Identification of aberrantly methylated genes in association with adult T-cell leukemia

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0610765104

21 January 2018

Pedigree disequilibrium tests for multilocus haplotypes.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0610765104

21 January 2018

Signal Transduction and Genes-to-Behaviors Pathways in Psychiatric Diseases

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0610765104

21 January 2018

Decreased in vitro production of interferon-gamma and interleukin-2 in whole blood of patients with schizophrenia during treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/17360599

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GOLD--graphical overview of linkage disequilibrium

1 reference

https://pubmed.ncbi.nlm.nih.gov/17360599

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The stanley foundation brain collection and neuropathology consortium

1 reference

https://pubmed.ncbi.nlm.nih.gov/17360599

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The neurobiology of dopamine signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/17360599

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased production of interleukin-2 in schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/17360599

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.0610765104

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2007PNAS..104.2815Y

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OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

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