(Q24683627)

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Activation of MTK1/MEKK4 by GADD45 through induced N-C dissociation and dimerization-mediated trans autophosphorylation of the MTK1 kinase domain

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scholarly article

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Activation of MTK1/MEKK4 by GADD45 through induced N-C dissociation and dimerization-mediated trans autophosphorylation of the MTK1 kinase domain (English)

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author name string

Zenshi Miyake

1

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Mutsuhiro Takekawa

2

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Qingyuan Ge

3

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Haruo Saito

4

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language of work or name

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publication date

April 2007

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Molecular and Cellular Biology

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27

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7

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2765-76

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MEKK4 is an effector of the embryonic TRAF4 for JNK activation

1 reference

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Regulation of MTK1/MEKK4 kinase activity by its N-terminal autoinhibitory domain and GADD45 binding

1 reference

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Direct activation of mitogen-activated protein kinase kinase kinase MEKK1 by the Ste20p homologue GCK and the adapter protein TRAF2.

1 reference

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1 reference

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1 reference

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MAP kinase pathways in the yeast Saccharomyces cerevisiae

1 reference

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A family of stress-inducible GADD45-like proteins mediate activation of the stress-responsive MTK1/MEKK4 MAPKKK

1 reference

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1 reference

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DNA damage-inducible transcripts in mammalian cells

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1 reference

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TAK1 mitogen-activated protein kinase kinase kinase is activated by autophosphorylation within its activation loop

1 reference

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1 reference

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7 April 2017

Conserved docking site is essential for activation of mammalian MAP kinase kinases by specific MAP kinase kinase kinases

1 reference

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7 April 2017

Myeloid differentiation (MyD)/growth arrest DNA damage (GADD) genes in tumor suppression, immunity and inflammation

1 reference

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Oligomerization of human Gadd45a protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899887

7 April 2017

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1 reference

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Regulation of the activity of MEK kinase 1 (MEKK1) by autophosphorylation within the kinase activation domain

1 reference

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7 April 2017

Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction

1 reference

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7 April 2017

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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GADD45beta/GADD45gamma and MEKK4 comprise a genetic pathway mediating STAT4-independent IFNgamma production in T cells.

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12 December 2020

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