(Q24684244)

English

The bisphosphonate acute phase response: rapid and copious production of proinflammatory cytokines by peripheral blood gd T cells in response to aminobisphosphonates is inhibited by statins

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scholarly article

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The bisphosphonate acute phase response: rapid and copious production of proinflammatory cytokines by peripheral blood gd T cells in response to aminobisphosphonates is inhibited by statins (English)

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author name string

R E Hewitt

1

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A Lissina

2

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A E Green

3

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E S Slay

4

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D A Price

5

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A K Sewell

6

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language of work or name

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publication date

January 2005

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Clinical and Experimental Immunology

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139

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1

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101-11

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Activation of CD4 T cells by Raf-independent effectors of Ras

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1809263

7 April 2017

Metastatic bone disease: clinical features, pathophysiology and treatment strategies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1809263

7 April 2017

Alendronate is a specific, nanomolar inhibitor of farnesyl diphosphate synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1809263

7 April 2017

Acute-phase proteins and other systemic responses to inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1809263

7 April 2017

Nonpeptide ligands for human gamma delta T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1809263

7 April 2017

Quantitative structure-activity relationships for gammadelta T cell activation by bisphosphonates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1809263

28 September 2017

Statins and their potential targets in multiple sclerosis therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1809263

28 September 2017

Statins as potential therapeutic agents in neuroinflammatory disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1809263

28 September 2017

Modulation of the inflammatory process by statins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1809263

28 September 2017

Requirement of species-specific interactions for the activation of human gamma delta T cells by pamidronate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1809263

28 September 2017

Bisphosphonates for the prevention of bone metastases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1809263

28 September 2017

Treatment of hypercalcemia of malignancy with bisphosphonates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1809263

28 September 2017

Human T cell receptor gammadelta cells recognize endogenous mevalonate metabolites in tumor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1809263

28 September 2017

Anti-inflammatory and immunomodulatory effects of statins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1809263

28 September 2017

The anti-tumour activity of bisphosphonates.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1809263

28 September 2017

Statins as anti-inflammatory agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1809263

28 September 2017

Isoprenoids as mediators of the biological effects of statins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1809263

28 September 2017

Pleiotropic effects of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1809263

28 September 2017

Vgamma2Vdelta2 T-cell receptor-mediated recognition of aminobisphosphonates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1809263

28 September 2017

Structure-activity relationships for inhibition of farnesyl diphosphate synthase in vitro and inhibition of bone resorption in vivo by nitrogen-containing bisphosphonates.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1809263

28 September 2017

Protein geranylgeranylation is required for osteoclast formation, function, and survival: inhibition by bisphosphonates and GGTI-298.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1809263

28 September 2017

New insights into the pharmacodynamic and pharmacokinetic properties of statins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1809263

28 September 2017

Treatment of patients with Paget's disease of bone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1809263

28 September 2017

Bisphosphonates: pharmacology, mechanisms of action and clinical uses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1809263

28 September 2017

Farnesol and geranylgeraniol prevent activation of caspases by aminobisphosphonates: biochemical evidence for two distinct pharmacological classes of bisphosphonate drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1809263

28 September 2017

Alendronate mechanism of action: geranylgeraniol, an intermediate in the mevalonate pathway, prevents inhibition of osteoclast formation, bone resorption, and kinase activation in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1809263

28 September 2017

Effects of tiludronate and ibandronate on the secretion of proinflammatory cytokines and nitric oxide from macrophages in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1809263

28 September 2017

An in vitro and in vivo study of cytokines in the acute-phase response associated with bisphosphonates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1809263

28 September 2017

Interleukin-6 and tumor necrosis factor alpha levels after bisphosphonates treatment in vitro and in patients with malignancy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1809263

28 September 2017

Pamidronate. A review of its pharmacological properties and therapeutic efficacy in resorptive bone disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1809263

28 September 2017

Quantitative structure--activity relations for gammadelta T cell activation by phosphoantigens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1809263

28 September 2017

The management of Paget's disease of bone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1809263

28 September 2017

Natural and synthetic non-peptide antigens recognized by human gamma delta T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1809263

28 September 2017

Lovastatin inhibits brain endothelial cell Rho-mediated lymphocyte migration and attenuates experimental autoimmune encephalomyelitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1809263

30 May 2018

Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1809263

30 May 2018

Overview of bisphosphonates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1809263

30 May 2018

Structure-activity relationships of various bisphosphonates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1809263

30 May 2018

Nitrogen-containing bisphosphonates inhibit isopentenyl pyrophosphate isomerase/farnesyl pyrophosphate synthase activity with relative potencies corresponding to their antiresorptive potencies in vitro and in vivo.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2249.2005.02665.X

21 January 2018

Farnesyl pyrophosphate synthase is the molecular target of nitrogen-containing bisphosphonates.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2249.2005.02665.X

21 January 2018

Targeting of tumor cells for human gammadelta T cells by nonpeptide antigens

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2249.2005.02665.X

21 January 2018

Essential contribution of germline-encoded lysine residues in Jgamma1.2 segment to the recognition of nonpeptide antigens by human gammadelta T cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2249.2005.02665.X

21 January 2018

Recognition mechanism of non-peptide antigens by human gammadelta T cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2249.2005.02665.X

21 January 2018

Effect of pravastatin on outcomes after cardiac transplantation.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2249.2005.02665.X

21 January 2018

A novel anti-inflammatory role for simvastatin in inflammatory arthritis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2249.2005.02665.X

21 January 2018

High-dose atorvastatin enhances the decline in inflammatory markers in patients with acute coronary syndromes in the MIRACL study

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2249.2005.02665.X

21 January 2018

A novel anti-inflammatory role of simvastatin in a murine model of allergic asthma

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2249.2005.02665.X

21 January 2018

Simvastatin has anti-inflammatory and antiatherosclerotic activities independent of plasma cholesterol lowering

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2249.2005.02665.X

21 January 2018

Reduction in serum levels of adhesion molecules, interleukin-6 and C-reactive protein following short-term low-dose atorvastatin treatment in patients with non-familial hypercholesterolemia.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2249.2005.02665.X

21 January 2018

The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2249.2005.02665.X

21 January 2018

Statins selectively inhibit leukocyte function antigen-1 by binding to a novel regulatory integrin site

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2249.2005.02665.X

21 January 2018

V gamma 4+ gamma delta T cells regulate airway hyperreactivity to methacholine in ovalbumin-sensitized and challenged mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2249.2005.02665.X

21 January 2018

Different potentials of gamma delta T cell subsets in regulating airway responsiveness: V gamma 1+ cells, but not V gamma 4+ cells, promote airway hyperreactivity, Th2 cytokines, and airway inflammation.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2249.2005.02665.X

21 January 2018

Recognition of nonpeptide antigens by human V gamma 9V delta 2 T cells requires contact with cells of human origin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1809263

28 November 2018

Statins prevent bisphosphonate-induced gamma,delta-T-cell proliferation and activation in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1809263

28 November 2018

3-D QSAR investigations of the inhibition of Leishmania major farnesyl pyrophosphate synthase by bisphosphonates.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1809263

28 November 2018

Anti-inflammatory Effects of Statins in Patients with Aortic Stenosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1809263

28 November 2018

Soluble intercellular adhesion molecule-1 and interleukin-6 levels reflect endothelial dysfunction in patients with primary hypercholesterolaemia treated with atorvastatin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1809263

28 November 2018

Pharmacokinetics and pharmacodynamics of zoledronic acid in cancer patients with bone metastases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1809263

28 November 2018

Are early clinical effects of cholesterol lowering mediated through effects on inflammation?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1809263

28 November 2018

Identification of a bisphosphonate that inhibits isopentenyl diphosphate isomerase and farnesyl diphosphate synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1809263

28 November 2018

In vivo anti-inflammatory effect of statins is mediated by nonsterol mevalonate products

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1809263

28 November 2018

Gamma/delta T-cell stimulation by pamidronate

1 reference

https://pubmed.ncbi.nlm.nih.gov/15606619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Contrasting effects of alendronate and clodronate on RAW 264 macrophages: the role of a bisphosphonate metabolite

1 reference

https://pubmed.ncbi.nlm.nih.gov/15606619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Negative regulation of airway responsiveness that is dependent on gammadelta T cells and independent of alphabeta T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15606619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HMG-CoA reductase inhibition: anti-inflammatory effects beyond lipid lowering?

1 reference

https://pubmed.ncbi.nlm.nih.gov/15606619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dose-proportional pharmacokinetics of risedronate on single-dose oral administration to healthy volunteers

1 reference

https://pubmed.ncbi.nlm.nih.gov/15606619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of gammadelta T cells by aminobisphosphonates and induction of antiplasma cell activity in multiple myeloma

1 reference

https://pubmed.ncbi.nlm.nih.gov/15606619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Statins as a newly recognized type of immunomodulator

1 reference

https://pubmed.ncbi.nlm.nih.gov/15606619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of postmenopausal osteoporosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15606619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro effect of (3-amino-1-hydroxypropylidene)-1,1-bisphosphonic acid (APD) on the function of mononuclear phagocytes in lymphocyte proliferation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15606619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The acute-phase response after bisphosphonate administration

1 reference

https://pubmed.ncbi.nlm.nih.gov/15606619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Side-effects of pamidronate

1 reference

https://pubmed.ncbi.nlm.nih.gov/15606619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Close correlation between Daudi and mycobacterial antigen recognition by human gamma delta T cells and expression of V9JPC1 gamma/V2DJC delta-encoded T cell receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/15606619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of IgE responses to inhaled antigen in mice by antigen-specific gamma delta T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15606619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pamidronate: an unrecognized problem in gastrointestinal tolerability

1 reference

https://pubmed.ncbi.nlm.nih.gov/15606619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6 and the acute phase response during treatment of patients with Paget's disease with the nitrogen-containing bisphosphonate dimethylaminohydroxypropylidene bisphosphonate

1 reference

https://pubmed.ncbi.nlm.nih.gov/15606619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Primary amino-bisphosphonates: a new class of gastrotoxic drugs--comparison of alendronate and aspirin

1 reference

https://pubmed.ncbi.nlm.nih.gov/15606619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bisphosphonates: mechanisms of action

1 reference

https://pubmed.ncbi.nlm.nih.gov/15606619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Requirement for gammadelta T cells in allergic airway inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15606619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1365-2249.2005.02665.X

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