(Q24802291)

English

Endotoxin leads to rapid subcellular re-localization of hepatic RXRalpha: A novel mechanism for reduced hepatic gene expression in inflammation

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scholarly article

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Endotoxin leads to rapid subcellular re-localization of hepatic RXRalpha: A novel mechanism for reduced hepatic gene expression in inflammation (English)

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1 reference

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author name string

Romi Ghose

1

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Tracy L Zimmerman

2

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Sundararajah Thevananther

3

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Saul J Karpen

4

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publication date

16 August 2004

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Nuclear receptor

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2

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4

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1

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describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC514570/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

https://scigraph.springernature.com/pub.10.1186/1478-1336-2-4

0 references

Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis

1 reference

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7 April 2017

Phenobarbital-responsive nuclear translocation of the receptor CAR in induction of the CYP2B gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514570

7 April 2017

The nuclear receptor superfamily: the second decade

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514570

7 April 2017

Molecular mechanism of nuclear translocation of an orphan nuclear receptor, SXR

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514570

7 April 2017

JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514570

7 April 2017

Interleukin-1 beta-mediated suppression of RXR:RAR transactivation of the Ntcp promoter is JNK-dependent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514570

7 April 2017

The RXR heterodimers and orphan receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514570

7 April 2017

The expression of CYP2B6, CYP2C9 and CYP3A4 genes: a tangle of networks of nuclear and steroid receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514570

28 September 2017

Organ-specific alterations in RAR alpha:RXR alpha abundance regulate rat Mrp2 (Abcc2) expression in obstructive cholestasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514570

28 September 2017

Nuclear receptor regulation of hepatic function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514570

28 September 2017

Hepatocyte-specific mutation establishes retinoid X receptor alpha as a heterodimeric integrator of multiple physiological processes in the liver.

1 reference

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28 September 2017

Modulating nuclear receptor function: may the phos be with you

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514570

28 September 2017

Endotoxin downregulates rat hepatic ntcp gene expression via decreased activity of critical transcription factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514570

28 September 2017

CCAAT/enhancer binding protein alpha regulates p21 protein and hepatocyte proliferation in newborn mice

1 reference

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28 September 2017

Steroid hormone receptors and their regulation by phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514570

28 September 2017

Multiple factors regulate the rat liver basolateral sodium-dependent bile acid cotransporter gene promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514570

28 September 2017

Molecular mechanisms of endotoxin activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514570

28 September 2017

Receptor-dependent mechanisms of cell stimulation by bacterial endotoxin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514570

28 September 2017

Dimerization with retinoid X receptors promotes nuclear localization and subnuclear targeting of vitamin D receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514570

30 May 2018

The acute phase response is associated with retinoid X receptor repression in rodent liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514570

30 May 2018

Bacterial lipopolysaccharide activates nuclear factor-kappaB through interleukin-1 signaling mediators in cultured human dermal endothelial cells and mononuclear phagocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514570

30 May 2018

Hepatocyte transport of bile acids and organic anions in endotoxemic rats: impaired uptake and secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514570

30 May 2018

Rapid transcriptional suppression of rat cytochrome P450 genes by endotoxin treatment and its inhibition by curcumin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514570

28 November 2018

Effects of proinflammatory cytokines on rat organic anion transporters during toxic liver injury and cholestasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514570

28 November 2018

The AF-1 and AF-2 domains of RAR gamma 2 and RXR alpha cooperate for triggering the transactivation and the degradation of RAR gamma 2/RXR alpha heterodimers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514570

28 November 2018

Repression of farnesoid X receptor during the acute phase response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514570

28 November 2018

Nuclear export of glucocorticoid receptor is enhanced by c-Jun N-terminal kinase-mediated phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514570

28 November 2018

Increased hepatobiliary and fecal cholesterol excretion upon activation of the liver X receptor is independent of ABCA1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514570

28 November 2018

Redundant pathways for negative feedback regulation of bile acid production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514570

28 November 2018

Reduction in cytochrome P-450 enzyme expression is associated with repression of CAR (constitutive androstane receptor) and PXR (pregnane X receptor) in mouse liver during the acute phase response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514570

28 November 2018

Down-regulation of cholesterol 7alpha-hydroxylase (CYP7A1) gene expression by bile acids in primary rat hepatocytes is mediated by the c-Jun N-terminal kinase pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514570

28 November 2018

Expression of the bile salt export pump is maintained after chronic cholestasis in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514570

28 November 2018

Clinicopathology conferences: inflammation-induced cholestasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15312234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subcellular distribution of normal and mutant vitamin D receptors in living cells. Studies with a novel fluorescent ligand

1 reference

https://pubmed.ncbi.nlm.nih.gov/15312234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of retinoid signalling through NGF-induced nuclear export of NGFI-B

1 reference

https://pubmed.ncbi.nlm.nih.gov/15312234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stress pathway activation induces phosphorylation of retinoid X receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/15312234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatic expression of PPARα, a molecular target of fibrates, is regulated during inflammation in a gender-specific manner

1 reference

https://pubmed.ncbi.nlm.nih.gov/15312234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dimerization with retinoid X receptors and phosphorylation modulate the retinoic acid-induced degradation of retinoic acid receptors alpha and gamma through the ubiquitin-proteasome pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/15312234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The rat canalicular conjugate export pump (Mrp2) is down-regulated in intrahepatic and obstructive cholestasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15312234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hyperphosphorylation of the retinoid X receptor alpha by activated c-Jun NH2-terminal kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/15312234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of hepatocyte bile salt transporters by endotoxin and inflammatory cytokines in rodents

1 reference

https://pubmed.ncbi.nlm.nih.gov/15312234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1478-1336-2-4

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