(Q24807027)

English

Polymorphism in the Plasmodium falciparum chloroquine-resistance transporter protein links verapamil enhancement of chloroquine sensitivity with the clinical efficacy of amodiaquine

scientific article published on September 19, 2003

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scholarly article

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Polymorphism in the Plasmodium falciparum chloroquine-resistance transporter protein links verapamil enhancement of chloroquine sensitivity with the clinical efficacy of amodiaquine (English)

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Plasmodium falciparum

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David C Warhurst

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David C Warhurst

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publication date

19 September 2003

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full work available at URL

https://malariajournal.biomedcentral.com/counter/pdf/10.1186/1475-2875-2-31

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14599295

28 March 2024

https://europepmc.org/articles/PMC269985

online access status

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Europe PubMed Central

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14599295

28 March 2024

https://europepmc.org/articles/PMC269985?pdf=render

Portable Document Format

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14599295

28 March 2024

Malaria Journal

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2

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31

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1

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https://scigraph.springernature.com/pub.10.1186/1475-2875-2-31

1 reference

9 September 2019

https://scigraph.springernature.com/pub.10.1186/1475-2875-2-31

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X-ray structure of a ClC chloride channel at 3.0 A reveals the molecular basis of anion selectivity

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7 April 2017

Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum

1 reference

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7 April 2017

Genetic diversity and chloroquine selective sweeps in Plasmodium falciparum

1 reference

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7 April 2017

Mutations in the P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistance

1 reference

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7 April 2017

pfcrt polymorphism and chloroquine resistance in Plasmodium falciparum strains isolated in Cambodia

1 reference

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28 September 2017

Lysosomes and drug resistance in malaria

1 reference

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28 September 2017

Chloroquine resistance in Plasmodium falciparum malaria parasites conferred by pfcrt mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=269985

28 September 2017

Evolution of a unique Plasmodium falciparum chloroquine-resistance phenotype in association with pfcrt polymorphism in Papua New Guinea and South America

1 reference

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28 September 2017

The public health impact of chloroquine resistance in Africa

1 reference

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28 September 2017

The structure of malaria pigment beta-haematin

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28 September 2017

Three-dimensional structure of membrane and surface proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=269985

28 September 2017

Rapid chloroquine efflux phenotype in both chloroquine-sensitive and chloroquine-resistant Plasmodium falciparum. A correlation of chloroquine sensitivity with energy-dependent drug accumulation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=269985

28 September 2017

Amodiaquine and hydroxychloroquine resistance in Plasmodium falciparum.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=269985

30 May 2018

Analysis of the antimalarial drug resistance protein Pfcrt expressed in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=269985

30 May 2018

Structure-activity relationships in 4-aminoquinoline antiplasmodials. The role of the group at the 7-position

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=269985

30 May 2018

Alternative mutations at position 76 of the vacuolar transmembrane protein PfCRT are associated with chloroquine resistance and unique stereospecific quinine and quinidine responses in Plasmodium falciparum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=269985

30 May 2018

Evidence for different mechanisms of chloroquine resistance in 2 Plasmodium species that cause human malaria.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=269985

30 May 2018

Physicochemical properties correlated with drug resistance and the reversal of drug resistance in Plasmodium falciparum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=269985

30 May 2018

Ferriprotoporphyrin IX fulfills the criteria for identification as the chloroquine receptor of malaria parasites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=269985

30 May 2018

Lysosomes, pH and the Anti-malarial Action of Chloroquine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=269985

30 May 2018

Reversal of chloroquine resistance in Plasmodium falciparum by verapamil

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=269985

30 May 2018

Efflux of chloroquine from Plasmodium falciparum: mechanism of chloroquine resistance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=269985

30 May 2018

A comparison of the in vitro activities of amodiaquine and desethylamodiaquine against isolates of Plasmodium falciparum.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=269985

30 May 2018

Several alleles of the multidrug-resistance gene are closely linked to chloroquine resistance in Plasmodium falciparum

1 reference

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30 May 2018

[Malaria in Amapa. Observations on the abnormal behavior of Plasmodium falciparum in treatment with 4-aminoquinolines.]

1 reference

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28 November 2018

Antimalarial drugs influence the pH dependent solubility of heme via apparent nucleation phenomena.

1 reference

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28 November 2018

A molecular marker for chloroquine-resistant falciparum malaria

1 reference

https://pubmed.ncbi.nlm.nih.gov/14599295

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amodiaquine as a prodrug: importance of metabolite(s) in the antimalarial effect of amodiaquine in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/14599295

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1475-2875-2-31

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9 September 2019

https://scigraph.springernature.com/pub.10.1186/1475-2875-2-31

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