(Q26747530)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27199750%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

review article

1 reference

title

Cysteine Proteases: Modes of Activation and Future Prospects as Pharmacological Targets (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27199750%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27199750%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

author name string

Sonia Verma

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27199750%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Kailash C Pandey

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27199750%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

language of work or name

English

0 references

publication date

25 April 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27199750%20AND%20SRC:MED&resulttype=core&format=json

Frontiers in Pharmacology

2 April 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27199750%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

volume

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27199750%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

page(s)

107

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27199750%20AND%20SRC:MED&resulttype=core&format=json

The proteome of lysosomes

2 April 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

Molecular mechanisms for the conversion of zymogens to active proteolytic enzymes

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

Structure of human procathepsin L reveals the molecular basis of inhibition by the prosegment

7 April 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

7 April 2017

https://api.crossref.org/works/10.3389%2FFPHAR.2016.00107

7 January 2021

inferred from DOI database lookup

Cysteine cathepsins: from structure, function and regulation to new frontiers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

The crystal and molecular structures of a cathepsin K:chondroitin sulfate complex

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

Structural and Functional Relationships in the Virulence-associated Cathepsin L Proteases of the Parasitic Liver Fluke, Fasciola hepatica

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

Crystal structure of human procathepsin X: a cysteine protease with the proregion covalently linked to the active site cysteine

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

Crystal structure of wild-type human procathepsin K

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

Structure of rat procathepsin B: model for inhibition of cysteine protease activity by the proregion

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

Crystal structures of human procathepsin B at 3.2 and 3.3 Angstroms resolution reveal an interaction motif between a papain-like cysteine protease and its propeptide

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

Hemoglobin metabolism in the malaria parasite Plasmodium falciparum

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

The Ionic and hydrophobic interactions are required for the auto activation of cysteine proteases of Plasmodium falciparum

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

Autocatalytic processing of recombinant human procathepsin L. Contribution of both intermolecular and unimolecular events in the processing of procathepsin L in vitro

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

Emerging roles for cysteine proteases in human biology

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

Surface activation of pro-cathepsin L

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

The mechanism by which a propeptide-encoded pH sensor regulates spatiotemporal activation of furin.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

Structure-function of falcipains: malarial cysteine proteases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

Falcipains and other cysteine proteases of malaria parasites

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

Secreted cysteine proteases of the carcinogenic liver fluke, Opisthorchis viverrini: regulation of cathepsin F activation by autocatalysis and trans-processing by cathepsin B

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

Intracellular trafficking of lysosomal proteins and lysosomes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

Inhibition of a viral enzyme by a small-molecule dimer disruptor

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

Regulatory elements within the prodomain of Falcipain-2, a cysteine protease of the malaria parasite Plasmodium falciparum

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

Hemoglobin cleavage site-specificity of the Plasmodium falciparum cysteine proteases falcipain-2 and falcipain-3.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

The importance of pH in regulating the function of the Fasciola hepatica cathepsin L1 cysteine protease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

Autocatalytic processing of procathepsin B is triggered by proenzyme activity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

The origin and evolution of plant cystatins and their target cysteine proteinases indicate a complex functional relationship

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

Nelfinavir, A lead HIV protease inhibitor, is a broad-spectrum, anticancer agent that induces endoplasmic reticulum stress, autophagy, and apoptosis in vitro and in vivo

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

Glycosaminoglycans facilitate procathepsin B activation through disruption of propeptide-mature enzyme interactions

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

Emerging roles of cysteine cathepsins in disease and their potential as drug targets.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

Role of cathepsin K in normal joints and in the development of arthritis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

Identification of a pH sensor in the furin propeptide that regulates enzyme activation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

Processing of human cathepsin D is independent of its catalytic function and auto-activation: involvement of cathepsins L and B.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

The Plasmodium falciparum cysteine protease falcipain-2 captures its substrate, hemoglobin, via a unique motif

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

Gene disruption confirms a critical role for the cysteine protease falcipain-2 in hemoglobin hydrolysis by Plasmodium falciparum

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

Functional expression and characterization of Schistosoma mansoni cathepsin B and its trans-activation by an endogenous asparaginyl endopeptidase

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

Human and parasitic papain-like cysteine proteases: their role in physiology and pathology and recent developments in inhibitor design.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

Cysteine proteases of malaria parasites: targets for chemotherapy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

Cysteine proteases of parasitic organisms

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

The lysosomal cysteine proteases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

Human cathepsin X: a novel cysteine protease of the papain family with a very short proregion and unique insertions

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

Autocatalytic activation of human cathepsin K.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

Lysine-based structure in the proregion of procathepsin L is the recognition site for mannose phosphorylation.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

The proregion of cathepsin L is required for proper folding, stability, and ER exit

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

Cysteine cathepsin activity regulation by glycosaminoglycans

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

The enigmatic asparaginyl endopeptidase of helminth parasites

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

Autocatalytic processing of recombinant human procathepsin B is a bimolecular process.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

Expression and partial characterization of a cathepsin B-like enzyme (Sm31) and a proposed 'haemoglobinase' (Sm32) from Schistosoma mansoni

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

Rat procathepsin B. Proteolytic processing to the mature form in vitro.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

Cathepsin L1, the major protease involved in liver fluke (Fasciola hepatica) virulence: propetide cleavage sites and autoactivation of the zymogen secreted from gastrodermal cells

31 May 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2016.00107

Human recombinant pro-dipeptidyl peptidase I (cathepsin C) can be activated by cathepsins L and S but not by autocatalytic processing

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2016.00107

Cathepsin K is involved in development of psoriasis-like skin lesions through TLR-dependent Th17 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2016.00107

Conformational flexibility and allosteric regulation of cathepsin K.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2016.00107

Independent intramolecular mediators of folding, activity, and inhibition for the Plasmodium falciparum cysteine protease falcipain-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2016.00107

Comprehensive search for cysteine cathepsins in the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2016.00107

Binding of chondroitin 4-sulfate to cathepsin S regulates its enzymatic activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2016.00107

Gene disruptions demonstrate independent roles for the four falcipain cysteine proteases of Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2016.00107

Folding of the Plasmodium falciparum cysteine protease falcipain-2 is mediated by a chaperone-like peptide and not the prodomain

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2016.00107

Falcipain cysteine proteases require bipartite motifs for trafficking to the Plasmodium falciparum food vacuole

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2016.00107

Recombinant human procathepsin S is capable of autocatalytic processing at neutral pH in the presence of glycosaminoglycans

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2016.00107

Maturation of human procathepsin B. Proenzyme activation and proteolytic processing of the precursor to the mature proteinase, in vitro, are primarily unimolecular processes.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

Processing of the papain precursor. The ionization state of a conserved amino acid motif within the Pro region participates in the regulation of intramolecular processing.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4842899

Evidence that aspartic proteinase is involved in the proteolytic processing event of procathepsin L in lysosomes

28 November 2018

1 reference

12 December 2020

The cysteine proteinases of Schistosoma mansoni cercariae

1 reference

12 December 2020

Effect of protease inhibitors on angiotensin-converting enzyme activity in human T-lymphocytes

1 reference

12 December 2020

Collagenolytic activity of cathepsin K is specifically modulated by cartilage-resident chondroitin sulfates

1 reference

12 December 2020

Schistosome asparaginyl endopeptidase SM32 in hemoglobin digestion

1 reference

12 December 2020

Protein-protein interaction inhibitors get into the groove

1 reference

12 December 2020

The Autoactivation of Trypsinogen

1 reference

12 December 2020

Potency and selectivity of the cathepsin L propeptide as an inhibitor of cysteine proteases

1 reference

12 December 2020

Cysteine proteinase activity regulation. A possible role of heparin and heparin-like glycosaminoglycans

1 reference

12 December 2020

Activating the cathepsin B1 of a parasite: a major route with alternative pathways?

1 reference

12 December 2020

Structural basis for specificity of papain-like cysteine protease proregions toward their cognate enzymes

1 reference

12 December 2020

Identifiers

DOI

10.3389/FPHAR.2016.00107

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27199750%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27199750%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27199750%20AND%20SRC:MED&resulttype=core&format=json