(Q44750364)

English

Cathepsin L1, the major protease involved in liver fluke (Fasciola hepatica) virulence: propetide cleavage sites and autoactivation of the zymogen secreted from gastrodermal cells

scientific article published on 30 January 2004

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Europe PubMed Central

PubMed publication ID

5 December 2017

Cathepsin L1, the major protease involved in liver fluke (Fasciola hepatica) virulence: propetide cleavage sites and autoactivation of the zymogen secreted from gastrodermal cells (English)

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Europe PubMed Central

PubMed publication ID

5 December 2017

Fasciola hepatica

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based on heuristic

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based on heuristic

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4

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Europe PubMed Central

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5 December 2017

Sheila M Donnelly

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5 December 2017

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Aaron G Maule

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Peter R Collins

1

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Europe PubMed Central

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5 December 2017

Colin M Stack

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Europe PubMed Central

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5 December 2017

Sandra M O'Neill

3

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Europe PubMed Central

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5 December 2017

Thecla Ryan

5

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Europe PubMed Central

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5 December 2017

Gerard P Brennan

6

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Europe PubMed Central

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5 December 2017

Angela Mousley

7

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Europe PubMed Central

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5 December 2017

Michael Stewart

8

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Europe PubMed Central

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5 December 2017

John P Dalton

10

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5 December 2017

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publication date

30 January 2004

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5 December 2017

Journal of Biological Chemistry

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5 December 2017

279

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Europe PubMed Central

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5 December 2017

17

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Europe PubMed Central

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5 December 2017

17038-17046

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Europe PubMed Central

PubMed publication ID

5 December 2017

Cathepsin L proteinase secreted by Fasciola hepatica in vitro prevents antibody-mediated eosinophil attachment to newly excysted juveniles.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308831200

21 January 2018

Fasciola hepatica infection downregulates Th1 responses in mice.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308831200

21 January 2018

Fasciola hepatica cathepsin L cysteine proteinase suppresses Bordetella pertussis-specific interferon-gamma production in vivo.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308831200

21 January 2018

Correlation of specific antibody titre and avidity with protection in cattle immunized against Fasciola hepatica.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308831200

21 January 2018

Parasite vaccines--a reality?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308831200

21 January 2018

Functional expression of Fasciola hepatica cathepsin L1 in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308831200

21 January 2018

Autocatalytic processing of recombinant human procathepsin L. Contribution of both intermolecular and unimolecular events in the processing of procathepsin L in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308831200

21 January 2018

Autocatalytic processing of recombinant human procathepsin B is a bimolecular process

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308831200

21 January 2018

Protease pro region required for folding is a potent inhibitor of the mature enzyme.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308831200

21 January 2018

Protein memory through altered folding mediated by intramolecular chaperones.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308831200

21 January 2018

Role of the prosegment of Fasciola hepatica cathepsin L1 in folding of the catalytic domain.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308831200

21 January 2018

Surface activation of pro-cathepsin L

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308831200

21 January 2018

Multi-step processing of procathepsin L in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308831200

21 January 2018

Autocatalytic activation of human cathepsin K.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308831200

21 January 2018

Characterisation and expression of the Fasciola gigantica cathepsin L gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308831200

21 January 2018

Crystal structures of human procathepsin B at 3.2 and 3.3 Angstroms resolution reveal an interaction motif between a papain-like cysteine protease and its propeptide

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308831200

21 January 2018

Crystal structure of the wild-type human procathepsin B at 2.5 A resolution reveals the native active site of a papain-like cysteine protease zymogen

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308831200

21 January 2018

Processing of the papain precursor. The ionization state of a conserved amino acid motif within the Pro region participates in the regulation of intramolecular processing

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308831200

21 January 2018

Helminth vaccines: from mining genomic information for vaccine targets to systems used for protein expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308831200

21 January 2018

Cysteine proteinases mediate extracellular prohormone processing in the thyroid

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308831200

21 January 2018

Purification and characterisation of a second cathepsin L proteinase secreted by the parasitic trematode Fasciola hepatica

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308831200

21 January 2018

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308831200

21 January 2018

Isolation of a cDNA encoding Fasciola hepatica cathepsin L2 and functional expression in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308831200

21 January 2018

Electron microscope studies of Fasciola hepatica. XII. The fine structure of the gastrodermis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308831200

21 January 2018

Cloning and characterization of anti-cathepsin L single chain variable fragment whose expression inhibits procathepsin L secretion in human melanoma cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308831200

21 January 2018

Molecular cloning of human cathepsin O, a novel endoproteinase and homologue of rabbit OC2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308831200

21 January 2018

Cathepsin K, but not cathepsins B, L, or S, is abundantly expressed in human osteoclasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308831200

21 January 2018

Cathepsin B of Schistosoma mansoni. Purification and activation of the recombinant proenzyme secreted by Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308831200

21 January 2018

Cysteine proteases of parasitic organisms

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308831200

21 January 2018

Fasciola hepatica: An electron microscope autoradiographic study of protein synthesis and secretion by gut cells in tissue slices

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308831200

21 January 2018

Proteolytic degradation of host hemoglobin by schistosomes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308831200

21 January 2018

Thyroid functions of mouse cathepsins B, K, and L

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308831200

21 January 2018

Proteinases Secreted by Fasciola hepatica Degrade Extracelullar Matrix and Basement Membrane Components

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308831200

21 January 2018

Purification of a cathepsin L-like proteinase secreted by adult Fasciola hepatica

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308831200

21 January 2018

Function of the propeptide region in recombinant expression of active procathepsin L in Escherichia coli

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308831200

21 January 2018

The propeptide of Fasciola hepatica cathepsin L is a potent and selective inhibitor of the mature enzyme

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308831200

21 January 2018

pH-induced Conformational Transitions of the Propeptide of Human Cathepsin L

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308831200

21 January 2018

Identification of internal autoproteolytic cleavage sites within the prosegments of recombinant procathepsin B and procathepsin S. Contribution of a plausible unimolecular autoproteolytic event for the processing of zymogens belonging to the papain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308831200

21 January 2018

Thiol proteases released in vitro by Fasciola hepatica

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308831200

21 January 2018

Stability studies on the cathepsin L proteinase of the helminth parasite, Fasciola hepatica

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308831200

21 January 2018

Observations on the nutrition of digenetic trematodes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308831200

21 January 2018

Schistosoma mansoni: Differential Expression of Cathepsins L1 and L2 Suggests Discrete Biological Functions for Each Enzyme

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308831200

21 January 2018

Participation of cathepsin L on bone resorption

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308831200

21 January 2018

Cysteine proteinase inhibitors decrease articular cartilage and bone destruction in chronic inflammatory arthritis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308831200

21 January 2018

Identifiers

10.1074/JBC.M308831200

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

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