(Q26769952)

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4 March 2020

1 reference

23 November 2020

Characteristics of Tau and Its Ligands in PET Imaging (English)

1 reference

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4 March 2020

3 references

25 April 2019

11 December 2019

19 December 2019

4 references

25 April 2019

11 December 2019

19 December 2019

23 November 2020

cytoskeletal proteins

1 reference

11 December 2019

1 reference

19 December 2019

positron emission tomography

1 reference

23 November 2020

4

1 reference

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4 March 2020

Kazuhiko Yanai

5

1 reference

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4 March 2020

author name string

Ryuichi Harada

1

1 reference

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4 March 2020

Nobuyuki Okamura

2

1 reference

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4 March 2020

Shozo Furumoto

3

1 reference

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4 March 2020

Hiroyuki Arai

6

1 reference

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4 March 2020

Yukitsuka Kudo

7

1 reference

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4 March 2020

language of work or name

English

0 references

publication date

6 January 2016

5 references

25 April 2019

11 December 2019

19 December 2019

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4 March 2020

23 November 2020

6 references

25 April 2019

11 December 2019

19 December 2019

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4 March 2020

23 November 2020

6

1 reference

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4 March 2020

issue

1

1 reference

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4 March 2020

page(s)

7

1 reference

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Creative Commons Attribution

4 March 2020

copyright license

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25 April 2019

11 December 2019

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on focus list of Wikimedia project

ScienceSource

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cites work

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7 April 2017

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7 April 2017

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High affinity radiopharmaceuticals based upon lansoprazole for PET imaging of aggregated tau in Alzheimer's disease and progressive supranuclear palsy: synthesis, preclinical evaluation, and lead selection

7 April 2017

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Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease

7 April 2017

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7 April 2017

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Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease

7 April 2017

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7 April 2017

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7 April 2017

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Longitudinal Assessment of Tau Pathology in Patients with Alzheimer's Disease Using [18F]THK-5117 Positron Emission Tomography.

28 September 2017

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Validating novel tau positron emission tomography tracer [F-18]-AV-1451 (T807) on postmortem brain tissue

28 September 2017

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PET Quantification of Tau Pathology in Human Brain with 11C-PBB3.

28 September 2017

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Visualization of regional tau deposits using (3)H-THK5117 in Alzheimer brain tissue

28 September 2017

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In vivo characterization of chronic traumatic encephalopathy using [F-18]FDDNP PET brain imaging.

28 September 2017

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Tau Positron Emission Tomography (PET) Imaging: Past, Present, and Future

28 September 2017

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Ultrastructural differences in pretangles between Alzheimer disease and corticobasal degeneration revealed by comparative light and electron microscopy

28 September 2017

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[18F]-T807 tauopathy PET imaging in chronic traumatic encephalopathy

28 September 2017

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28 September 2017

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The evolution of preclinical Alzheimer's disease: implications for prevention trials

28 September 2017

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28 September 2017

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28 September 2017

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Tauopathy PET and amyloid PET in the diagnosis of chronic traumatic encephalopathies: studies of a retired NFL player and of a man with FTD and a severe head injury.

28 September 2017

1 reference

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Evaluation of [(11)C]N-Methyl Lansoprazole as a Radiopharmaceutical for PET Imaging of Tau Neurofibrillary Tangles.

28 September 2017

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Assessing THK523 selectivity for tau deposits in Alzheimer's disease and non-Alzheimer's disease tauopathies.

28 September 2017

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In vivo evaluation of a novel tau imaging tracer for Alzheimer's disease.

28 September 2017

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Alzheimer disease therapy--moving from amyloid-β to tau.

28 September 2017

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Imaging of tau pathology in a tauopathy mouse model and in Alzheimer patients compared to normal controls

28 September 2017

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PET imaging of neuropathology in tauopathies: progressive supranuclear palsy

28 September 2017

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Postmortem 3-D brain hemisphere cortical tau and amyloid-β pathology mapping and quantification as a validation method of neuropathology imaging.

28 September 2017

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A highly selective and specific PET tracer for imaging of tau pathologies

28 September 2017

1 reference

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Proline isomer-specific antibodies reveal the early pathogenic tau conformation in Alzheimer's disease

28 September 2017

1 reference

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National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease

28 September 2017

1 reference

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Protein binding in patients with late-life depression

28 September 2017

1 reference

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Long-term consequences of repetitive brain trauma: chronic traumatic encephalopathy

28 September 2017

1 reference

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Positron emission tomography of brain β-amyloid and τ levels in adults with Down syndrome

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4808801

Alzheimer's pathogenesis: is there neuron-to-neuron propagation?

28 September 2017

1 reference

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Corticobasal degeneration: a pathologically distinct 4R tauopathy

28 September 2017

1 reference

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Post-translational modifications of tau protein: implications for Alzheimer's disease.

28 September 2017

1 reference

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Interaction of the amyloid imaging tracer FDDNP with hallmark Alzheimer's disease pathologies

28 September 2017

1 reference

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Silver diagnosis in neuropathology: principles, practice and revised interpretation

28 September 2017

1 reference

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Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4808801

Imaging of CNS myelin by positron-emission tomography

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4808801

In vivo brain imaging of tangle burden in humans

28 September 2017

1 reference

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Argyrophilic grain disease is a sporadic 4-repeat tauopathy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4808801

Comparative analysis of an improved thioflavin-s stain, Gallyas silver stain, and immunohistochemistry for neurofibrillary tangle demonstration on the same sections.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4808801

Pathologic correlates of nondemented aging, mild cognitive impairment, and early-stage Alzheimer's disease

28 September 2017

1 reference

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Binding characteristics of radiofluorinated 6-dialkylamino-2-naphthylethylidene derivatives as positron emission tomography imaging probes for beta-amyloid plaques in Alzheimer's disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4808801

Neuropathologic differentiation of progressive supranuclear palsy and corticobasal degeneration

28 September 2017

1 reference

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Glial inclusions in CNS degenerative diseases.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4808801

Neocortical neurofibrillary tangles correlate with dementia severity in Alzheimer's disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4808801

Staging of Alzheimer's disease-related neurofibrillary changes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4808801

X-ray diffraction from intraneuronal paired helical filaments and extraneuronal amyloid fibers in Alzheimer disease indicates cross-beta conformation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4808801

The switch of tau protein to an Alzheimer-like state includes the phosphorylation of two serine-proline motifs upstream of the microtubule binding region

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4808801

Differential distribution of neurofibrillary tangles in the cerebral cortex of dementia pugilistica and Alzheimer's disease cases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4808801

Conformational features of tau fibrils from Alzheimer's disease brain are faithfully propagated by unmodified recombinant protein

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4808801

The influence of phospho-τ on dendritic spines of cortical pyramidal neurons in patients with Alzheimer's disease

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4808801

[(18)F]T807, a novel tau positron emission tomography imaging agent for Alzheimer's disease

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4808801

Tau-positive neurons in corticobasal degeneration and Alzheimer's disease--distinction by thiazin red and silver impregnations

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4808801

Sequence of Abeta-protein deposition in the human medial temporal lobe.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4808801

Tau pathology in two Dutch families with mutations in the microtubule-binding region of tau

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4808801

Pick's disease: hyperphosphorylated tau protein segregates to the somatoaxonal compartment.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4808801

A sequence of cytoskeleton changes related to the formation of neurofibrillary tangles and neuropil threads

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4808801

Silver staining of Alzheimer's neurofibrillary changes by means of physical development.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4808801

[A semiquantitative study on Alzheimer neurofibrillary tangles demonstrated immunohistochemically with anti-tau antibodies, in the brains of non-demented and demented old people]

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4808801

Silver impregnation of Alzheimer's neurofibrillary changes counterstained for basophilic material and lipofuscin pigment.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4808801

Formic acid pretreatment enhances immunostaining of cerebral and systemic amyloids.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4808801

Tau proteins of Alzheimer paired helical filaments: abnormal phosphorylation of all six brain isoforms

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4808801

Appearance of paired nucleated, Tau-positive glia in patients with progressive supranuclear palsy brain tissue

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4808801

The biochemical pathway of neurofibrillary degeneration in aging and Alzheimer's disease.

31 May 2018

1 reference

https://api.crossref.org/works/10.3390%2FBIOM6010007

Quantitative neuropathologic analysis of Pick's disease cases: cortical distribution of Pick bodies and coexistence with Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FBIOM6010007

Office of Rare Diseases neuropathologic criteria for corticobasal degeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FBIOM6010007

Mutation-specific functional impairments in distinct tau isoforms of hereditary FTDP-17.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FBIOM6010007

Vulnerable neuronal subsets in Alzheimer's and Pick's disease are distinguished by their tau isoform distribution and phosphorylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FBIOM6010007

Alzheimer's Disease: Insolubility of Partially Purified Paired Helical Filaments in Sodium Dodecyl Sulfate and Urea

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FBIOM6010007

Paired Helical Filaments in Electron Microscopy of Alzheimer's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FBIOM6010007

Stages of the pathologic process in Alzheimer disease: age categories from 1 to 100 years.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FBIOM6010007

Quinoline and benzimidazole derivatives: candidate probes for in vivo imaging of tau pathology in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FBIOM6010007

[(18)F]THK-5117 PET for assessing neurofibrillary pathology in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FBIOM6010007

Imaging central nervous system myelin by positron emission tomography in multiple sclerosis using [methyl-¹¹C]-2-(4'-methylaminophenyl)- 6-hydroxybenzothiazole.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FBIOM6010007

21 January 2018

Brain amyloid imaging

1 reference

https://api.crossref.org/works/10.3390%2FBIOM6010007

The 2,6-disubstituted naphthalene derivative FDDNP labeling reliably predicts Congo red birefringence of protein deposits in brain sections of selected human neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FBIOM6010007

In vitro detection of (S)-naproxen and ibuprofen binding to plaques in the Alzheimer's brain using the positron emission tomography molecular imaging probe 2-(1-[6-[(2-[(18)F]fluoroethyl)(methyl)amino]-2-naphthyl]ethylidene)malononitrile

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FBIOM6010007

Comparison of the binding characteristics of [18F]THK-523 and other amyloid imaging tracers to Alzheimer's disease pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FBIOM6010007

Amyloid tracers detect multiple binding sites in Alzheimer's disease brain tissue.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FBIOM6010007

Synthesis and preliminary evaluation of 2-arylhydroxyquinoline derivatives for tau imaging.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FBIOM6010007

Use of a benzimidazole derivative BF-188 in fluorescence multispectral imaging for selective visualization of tau protein fibrils in the Alzheimer's disease brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FBIOM6010007

Novel 18F-labeled arylquinoline derivatives for noninvasive imaging of tau pathology in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FBIOM6010007

18F-THK5351: A Novel PET Radiotracer for Imaging Neurofibrillary Pathology in Alzheimer Disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FBIOM6010007

Structure-Activity Relationship Study of Heterocyclic Phenylethenyl and Pyridinylethenyl Derivatives as Tau-Imaging Agents That Selectively Detect Neurofibrillary Tangles in Alzheimer's Disease Brains.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FBIOM6010007

PET of brain amyloid and tau in mild cognitive impairment.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FBIOM6010007

PET of brain prion protein amyloid in Gerstmann-Sträussler-Scheinker disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FBIOM6010007

Peripheral metabolism of [(18)F]FDDNP and cerebral uptake of its labelled metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FBIOM6010007

Radiosynthesis, photoisomerization, biodistribution, and metabolite analysis of 11C-PBB3 as a clinically useful PET probe for imaging of tau pathology.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FBIOM6010007

Identification of a major radiometabolite of [11C]PBB3.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FBIOM6010007

Non-invasive assessment of Alzheimer's disease neurofibrillary pathology using 18F-THK5105 PET.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FBIOM6010007

18F-THK523: a novel in vivo tau imaging ligand for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FBIOM6010007

Early clinical PET imaging results with the novel PHF-tau radioligand [F-18]-T807.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4808801

Molecular-imaging probe 2-(1-[6-[(2-fluoroethyl)(methyl) amino]-2-naphthyl]ethylidene) malononitrile labels prion plaques in vitro.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4808801

Localization of neurofibrillary tangles and beta-amyloid plaques in the brains of living patients with Alzheimer disease

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4808801

Different conformation of neuronal tau deposits distinguished by double immunofluorescence with AT8 and thiazin red combined with Gallyas method.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4808801

Evolution from pretangle neurons to neurofibrillary tangles monitored by thiazin red combined with Gallyas method and double immunofluorescence

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4808801

Comparison of the neurofibrillary pathology in Alzheimer's disease and familial presenile dementia with tangles

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26751494

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The pathological process underlying Alzheimer's disease in individuals under thirty

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26751494

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Binding Characteristics of Radiofluorinated 6-Dialkylamino-2-Naphthylethylidene Derivatives as Positron Emission Tomography Imaging Probes for β-Amyloid Plaques in Alzheimer's Disease

1 reference

https://api.crossref.org/works/10.3390%2FBIOM6010007

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.3390/BIOM6010007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26751494%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26751494%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26751494%20AND%20SRC:MED&resulttype=core&format=json