Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q26770250)
Watch
English
Age-related macular degeneration: Complement in action
scientific article
In more languages
edit
Statements
instance of
scholarly article
0 references
title
Age-related macular degeneration: Complement in action
(English)
0 references
main subject
macular degeneration
1 reference
based on heuristic
inferred from title
author
Menno van Lookeren Campagne
series ordinal
1
0 references
author name string
Erich C Strauss
series ordinal
2
0 references
Brian L Yaspan
series ordinal
3
0 references
language of work or name
English
0 references
publication date
June 2016
0 references
published in
Immunobiology
0 references
volume
221
0 references
issue
6
0 references
page(s)
733-9
0 references
cites work
The US twin study of age-related macular degeneration: relative roles of genetic and environmental influences
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Heredity and age-related macular degeneration. Observations in monozygotic twins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sibling correlations and segregation analysis of age-related maculopathy: the Beaver Dam Eye Study.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Decreased membrane complement regulators in the retinal pigmented epithelium contributes to age-related macular degeneration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanisms of age-related macular degeneration and therapeutic opportunities
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oxidized low-density-lipoprotein-induced injury in retinal pigment epithelium alters expression of the membrane complement regulatory factors CD46 and CD59 through exosomal and apoptotic bleb release
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Anaphylatoxins: their role in bacterial infection and inflammation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Age-related macular degeneration and the complement system
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic insights into age-related macular degeneration: controversies addressing risk, causality, and therapeutics
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Complement factor H related proteins (CFHRs)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic variants in the complement system predisposing to age-related macular degeneration: a review
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Complement factor H Y402H variant and risk of age-related macular degeneration in Asians: a systematic review and meta-analysis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Systemic complement inhibition with eculizumab for geographic atrophy in age-related macular degeneration: the COMPLETE study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic susceptibility, dietary antioxidants, and long-term incidence of age-related macular degeneration in two populations
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Geographic atrophy: clinical features and potential therapeutic approaches
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The pivotal role of the complement system in aging and age-related macular degeneration: hypothesis re-visited
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Complement activation and choriocapillaris loss in early AMD: implications for pathophysiology and therapy.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Familial aggregation of age-related maculopathy.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A twin study of age-related macular degeneration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related macular degeneration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Variation near complement factor I is associated with risk of advanced AMD
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
No evidence of association between complement factor I genetic variant rs10033900 and age-related macular degeneration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The International HapMap Project
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Complement factor H binds malondialdehyde epitopes and protects from oxidative stress
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CFH haplotypes without the Y402H coding variant show strong association with susceptibility to age-related macular degeneration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Common variation in three genes, including a noncoding variant in CFH, strongly influences risk of age-related macular degeneration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A common CFH haplotype, with deletion of CFHR1 and CFHR3, is associated with lower risk of age-related macular degeneration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Seven new loci associated with age-related macular degeneration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A functional variant in the CFI gene confers a high risk of age-related macular degeneration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A rare nonsynonymous sequence variant in C3 is associated with high risk of age-related macular degeneration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rare variants in CFI, C3 and C9 are associated with high risk of advanced age-related macular degeneration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a rare coding variant in complement 3 associated with age-related macular degeneration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A rare penetrant mutation in CFH confers high risk of age-related macular degeneration.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Complement C3 variant and the risk of age-related macular degeneration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Complement activation by photooxidation products of A2E, a lipofuscin constituent of the retinal pigment epithelium
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oxidative stress sensitizes retinal pigmented epithelial (RPE) cells to complement-mediated injury in a natural antibody-, lectin pathway-, and phospholipid epitope-dependent manner
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Smoke exposure causes endoplasmic reticulum stress and lipid accumulation in retinal pigment epithelium through oxidative stress and complement activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Extended haplotypes in the complement factor H (CFH) and CFH-related (CFHR) family of genes protect against age-related macular degeneration: characterization, ethnic distribution and evolutionary implications
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic association of apolipoprotein E with age-related macular degeneration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genomewide scans of complex human diseases: true linkage is hard to find
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An imbalance of human complement regulatory proteins CFHR1, CFHR3 and factor H influences risk for age-related macular degeneration (AMD)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Whole-exome sequencing identifies rare, functional CFH variants in families with macular degeneration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Complement factor H genetic variant and age-related macular degeneration: effect size, modifiers and relationship to disease subtype
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A phase ia dose-escalation study of the anti-factor D monoclonal antibody fragment FCFD4514S in patients with geographic atrophy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Complement factor H polymorphism in age-related macular degeneration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Complement factor H polymorphism and age-related macular degeneration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Complement factor H variant increases the risk of age-related macular degeneration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The retinal pigment epithelium in visual function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Complement activation by bisretinoid constituents of RPE lipofuscin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rare complement factor H variant associated with age-related macular degeneration in the Amish
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Current Clinical Trials in Dry AMD and the Definition of Appropriate Clinical Outcome Measures
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of Factor H and Related Proteins in Regulating Complement Activation in the Macula, and Relevance to Age-Related Macular Degeneration.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.IMBIO.2015.11.007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/J.IMBIO.2015.11.007
0 references
PubMed publication ID
26742632
0 references
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit
