(Q34620560)

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Oxidative stress sensitizes retinal pigmented epithelial (RPE) cells to complement-mediated injury in a natural antibody-, lectin pathway-, and phospholipid epitope-dependent manner

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scholarly article

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Europe PubMed Central

PubMed publication ID

3 August 2017

Oxidative stress sensitizes retinal pigmented epithelial (RPE) cells to complement-mediated injury in a natural antibody-, lectin pathway-, and phospholipid epitope-dependent manner (English)

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

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Nicole Thielens

object named as

Nicole M Thielens

7

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object named as

Steffen Thiel

6

0 references

V Michael Holers

8

object named as

V Michael Holers

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

author name string

Kusumam Joseph

1

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Liudmila Kulik

2

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Beth Coughlin

3

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Kannan Kunchithapautham

4

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Mausumi Bandyopadhyay

5

1 reference

Europe PubMed Central

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3 August 2017

Bärbel Rohrer

9

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Europe PubMed Central

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3 August 2017

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publication date

14 March 2013

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Europe PubMed Central

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3 August 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

3 August 2017

288

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

18

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

12753-12765

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Understanding age-related macular degeneration (AMD): relationships between the photoreceptor/retinal pigment epithelium/Bruch's membrane/choriocapillaris complex

1 reference

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Consequences of oxidative stress in age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3642321

7 July 2018

Matrix metalloproteinase activity creates pro-angiogenic environment in primary human retinal pigment epithelial cells exposed to complement

1 reference

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7 July 2018

Studies of the pattern recognition molecule H-ficolin: specificity and purification

1 reference

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Pathogenic natural antibodies propagate cerebral injury following ischemic stroke in mice

1 reference

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Complement factor H binds malondialdehyde epitopes and protects from oxidative stress

1 reference

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Cell culture model that mimics drusen formation and triggers complement activation associated with age-related macular degeneration

1 reference

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Mechanisms of mannose-binding lectin-associated serine proteases-1/3 activation of the alternative pathway of complement

1 reference

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Activation of the alternative complement pathway by mannose-binding lectin via a C2-bypass pathway

1 reference

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Anti-amyloid therapy protects against retinal pigmented epithelium damage and vision loss in a model of age-related macular degeneration.

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C-reactive protein and complement factor H in aged human eyes and eyes with age-related macular degeneration

1 reference

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7 July 2018

Sublytic membrane-attack-complex (MAC) activation alters regulated rather than constitutive vascular endothelial growth factor (VEGF) secretion in retinal pigment epithelium monolayers

1 reference

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7 July 2018

Lysosomal stress and lipid peroxidation products induce VEGF-121 and VEGF-165 expression in ARPE-19 cells

1 reference

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7 July 2018

Targeting of mannan-binding lectin-associated serine protease-2 confers protection from myocardial and gastrointestinal ischemia/reperfusion injury.

1 reference

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The alternative pathway is required, but not alone sufficient, for retinal pathology in mouse laser-induced choroidal neovascularization

1 reference

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7 July 2018

The significance of the complement system for the pathogenesis of age-related macular degeneration - current evidence and translation into clinical application

1 reference

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Pathway-based therapies for age-related macular degeneration: an integrated survey of emerging treatment alternatives

1 reference

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7 July 2018

Blockade of self-reactive IgM significantly reduces injury in a murine model of acute myocardial infarction

1 reference

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7 July 2018

Animals as models of age-related macular degeneration: an imperfect measure of the truth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3642321

7 July 2018

Lipid peroxidation products reduce lysosomal protease activities in human retinal pigment epithelial cells via two different mechanisms of action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3642321

7 July 2018

C1q differentially modulates phagocytosis and cytokine responses during ingestion of apoptotic cells by human monocytes, macrophages, and dendritic cells.

1 reference

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7 July 2018

Autoimmunity in retinal degeneration: autoimmune retinopathy and age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3642321

7 July 2018

Changes in retinal pigment epithelium related to cigarette smoke: possible relevance to smoking as a risk factor for age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3642321

7 July 2018

Oxidative stress renders retinal pigment epithelial cells susceptible to complement-mediated injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3642321

7 July 2018

Pathogenic natural antibodies recognizing annexin IV are required to develop intestinal ischemia-reperfusion injury

1 reference

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7 July 2018

A targeted inhibitor of the alternative complement pathway reduces angiogenesis in a mouse model of age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3642321

7 July 2018

Polymorphisms in mannan-binding lectin (MBL)-associated serine protease 2 affect stability, binding to MBL, and enzymatic activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3642321

7 July 2018

Residue Lys57 in the collagen-like region of human L-ficolin and its counterpart Lys47 in H-ficolin play a key role in the interaction with the mannan-binding lectin-associated serine proteases and the collectin receptor calreticulin.

1 reference

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The spectrum of complement alternative pathway-mediated diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3642321

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Measurement of factor H variants in plasma using variant-specific monoclonal antibodies: application to assessing risk of age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3642321

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Effects of an anti-VEGF-A monoclonal antibody on laser-induced choroidal neovascularization in mice: optimizing methods to quantify vascular changes.

1 reference

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Oxidative damage-induced inflammation initiates age-related macular degeneration.

1 reference

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Antibodies to oxidized low density lipoprotein: epidemiological studies and potential clinical applications in cardiovascular disease.

1 reference

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7 July 2018

VEGF modulation of retinal pigment epithelium resistance

1 reference

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7 July 2018

Role of MBL-associated serine protease (MASP) on activation of the lectin complement pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3642321

7 July 2018

Molecular genetics of AMD and current animal models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3642321

7 July 2018

Age-related macular degeneration (AMD): pathogenesis and therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3642321

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Drusen complement components C3a and C5a promote choroidal neovascularization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3642321

7 July 2018

M-ficolin, an innate immune defence molecule, binds patterns of acetyl groups and activates complement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3642321

7 July 2018

A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3642321

7 July 2018

Immunological factors in the pathogenesis and treatment of age-related macular degeneration

1 reference

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Role of complement and complement membrane attack complex in laser-induced choroidal neovascularization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3642321

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Identification of a specific self-reactive IgM antibody that initiates intestinal ischemia/reperfusion injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3642321

7 July 2018

Oxidative stress affects the junctional integrity of retinal pigment epithelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3642321

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Recombinant mannan-binding lectin (MBL) for therapy

1 reference

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Drusen proteome analysis: an approach to the etiology of age-related macular degeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3642321

7 July 2018

Complement activation and inflammatory processes in Drusen formation and age related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3642321

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An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related macular degeneration

1 reference

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Improvements on the purification of mannan-binding lectin and demonstration of its Ca(2+)-independent association with a C1s-like serine protease.

1 reference

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Reperfusion injury of ischemic skeletal muscle is mediated by natural antibody and complement

1 reference

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Evidence for protection against age-related macular degeneration by carotenoids and antioxidant vitamins

1 reference

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Molecular organization and function of the complement system

1 reference

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Are low inflammatory reactions involved in exudative age-related macular degeneration? Morphological and immunhistochemical analysis of AMD associated with basal deposits

1 reference

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21 January 2018

New insights on the structural/functional properties of recombinant human mannan-binding lectin and its variants

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.421891

21 January 2018

L-ficolin binding and lectin pathway activation by acetylated low-density lipoprotein.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.421891

21 January 2018

Activation of the lectin pathway by natural IgM in a model of ischemia/reperfusion injury.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.421891

21 January 2018

Genetic and environmental factors influencing the human factor H plasma levels

1 reference

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21 January 2018

Mice Deficient in Complement Receptors 1 and 2 Lack a Tissue Injury-Inducing Subset of the Natural Antibody Repertoire

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.421891

21 January 2018

Identification of anti-retinal antibodies in patients with age-related macular degeneration.

1 reference

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21 January 2018

Carboxyethylpyrrole protein adducts and autoantibodies, biomarkers for age-related macular degeneration.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.421891

21 January 2018

Complement factor h autoantibodies and age-related macular degeneration.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.421891

21 January 2018

Immunohistochemical localization of complement regulatory proteins in the human retina

1 reference

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26 October 2018

Changes in Blood Antioxidants and Several Lipid Peroxidation Products in Women with Age-Related Macular Degeneration

1 reference

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26 October 2018

Annexins in Bruch's membrane and drusen

1 reference

https://pubmed.ncbi.nlm.nih.gov/23493397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of Lipid Peroxidation-Related Protein Modifications on RPE Lysosomal Functions and POS Phagocytosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23493397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complement activation in retinal degeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/23493397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantifying changes in RPE and choroidal vasculature in eyes with age-related macular degeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/23493397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M112.421891

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

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