(Q26770676)

Variant of TREM2 Associated with the Risk of Alzheimer's Disease

volume

6

0 references

page(s)

632

0 references

cites work

1 reference

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Anti-inflammatory drugs and risk of Parkinson disease: A meta-analysis

7 April 2017

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Protective effects of NSAIDs on the development of Alzheimer disease

7 April 2017

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CNS immune privilege: hiding in plain sight

7 April 2017

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Structural and functional features of central nervous system lymphatic vessels

7 April 2017

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Neuroinflammation in Alzheimer's disease

7 April 2017

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Immune heterogeneity in neuroinflammation: dendritic cells in the brain

7 April 2017

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Nonsteroidal antiinflammatory drug use and the risk for Parkinson's disease

7 April 2017

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Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha

7 April 2017

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Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease

7 April 2017

1 reference

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Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders

7 April 2017

1 reference

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Mechanisms underlying inflammation in neurodegeneration

7 April 2017

1 reference

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Microglial physiology: unique stimuli, specialized responses

7 April 2017

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Neuroinflammation in Parkinson's disease: a target for neuroprotection?

7 April 2017

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NEURODEGENERATION. Alzheimer's and Parkinson's diseases: The prion concept in relation to assembled Aβ, tau, and α-synuclein

7 April 2017

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Microglia Versus Myeloid Cell Nomenclature during Brain Inflammation

28 September 2017

1 reference

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Immune attack: the role of inflammation in Alzheimer disease.

28 September 2017

1 reference

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Post-mortem analysis of neuroinflammatory changes in human Alzheimer's disease

28 September 2017

1 reference

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Infiltration of circulating myeloid cells through CD95L contributes to neurodegeneration in mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4679857

TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimer's disease mouse models.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4679857

Evaluation of an α synuclein sensitized dendritic cell based vaccine in a transgenic mouse model of Parkinson disease

28 September 2017

1 reference

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Convergent genetic and expression data implicate immunity in Alzheimer's disease

28 September 2017

1 reference

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Inflammatory dysregulation of blood monocytes in Parkinson's disease patients

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4679857

Combined treatment of amyloid-β₁₋₄₂-stimulated bone marrow-derived dendritic cells plus splenocytes from young mice prevents the development of Alzheimer's disease in APPswe/PSENldE9 mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4679857

Alzheimer's disease risk genes and mechanisms of disease pathogenesis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4679857

Polarization of the effects of autoimmune and neurodegenerative risk alleles in leukocytes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4679857

Microglia and brain macrophages in the molecular age: from origin to neuropsychiatric disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4679857

Microglial priming in neurodegenerative disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4679857

TREM2 in neurodegeneration: evidence for association of the p.R47H variant with frontotemporal dementia and Parkinson's disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4679857

Blood dendritic cell frequency declines in idiopathic Parkinson's disease and is associated with motor symptom severity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4679857

CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4679857

The role of inflammation in sporadic and familial Parkinson's disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4679857

A phenotypic change but not proliferation underlies glial responses in Alzheimer disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4679857

Cell therapy: a safe and efficacious therapeutic treatment for Alzheimer's disease in APP+PS1 mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4679857

Deciphering the mechanism underlying late-onset Alzheimer disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4679857

Brain dendritic cells: biology and pathology.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4679857

Autoimmunity, dendritic cells and relevance for Parkinson's disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4679857

The immunology of neurodegeneration

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4679857

Inflammation and adaptive immunity in Parkinson's disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4679857

Neuromelanin is an immune stimulator for dendritic cells in vitro

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4679857

Heterogeneity of CNS myeloid cells and their roles in neurodegeneration

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4679857

Flt3L controls the development of radiosensitive dendritic cells in the meninges and choroid plexus of the steady-state mouse brain

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4679857

Immunology meets neuroscience--opportunities for immune intervention in neurodegenerative diseases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4679857

Nomenclature of monocytes and dendritic cells in blood.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4679857

Systemic inflammatory cells fight off neurodegenerative disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4679857

The role and therapeutic potential of monocytic cells in Alzheimer's disease.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4679857

Breaking boundaries in neural-immune interactions

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4679857

CNS infiltration of peripheral immune cells: D-Day for neurodegenerative disease?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4679857

Regulation of innate immune responses in the brain

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4679857

Infiltration of CD4+ lymphocytes into the brain contributes to neurodegeneration in a mouse model of Parkinson disease.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4679857

Blocking TGF-beta-Smad2/3 innate immune signaling mitigates Alzheimer-like pathology

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4679857

Cognitive function over time in the Alzheimer's Disease Anti-inflammatory Prevention Trial (ADAPT): results of a randomized, controlled trial of naproxen and celecoxib

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4679857

CD11c/EYFP transgene illuminates a discrete network of dendritic cells within the embryonic, neonatal, adult, and injured mouse brain

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4679857

Blood-brain barrier pathology in Alzheimer's and Parkinson's disease: implications for drug therapy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4679857

Abeta-induced meningoencephalitis is IFN-gamma-dependent and is associated with T cell-dependent clearance of Abeta in a mouse model of Alzheimer's disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4679857

Cell biology of protein misfolding: the examples of Alzheimer's and Parkinson's diseases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4679857

Immunotherapeutic Approaches to Alzheimer's Disease

28 September 2017

1 reference

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Mouse and human dendritic cell subtypes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4679857

Peripheral inflammation increases the deleterious effect of CNS inflammation on the nigrostriatal dopaminergic system

28 September 2017

1 reference

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Interactions of the Alzheimer beta amyloid fragment (25-35) with peripheral blood dendritic cells.

31 May 2018

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Real-time in vivo imaging reveals the ability of monocytes to clear vascular amyloid beta.

31 May 2018

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Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease

21 January 2018

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Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease.

21 January 2018

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Distinct and non-redundant roles of microglia and myeloid subsets in mouse models of Alzheimer's disease.

21 January 2018

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Cyclooxygenase-2-positive macrophages infiltrate the Alzheimer's disease brain and damage the blood-brain barrier.

21 January 2018

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Characterization of peripheral hematopoietic stem cells and monocytes in Parkinson's disease.

21 January 2018

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Lasker Basic Medical Research Award. Dendritic cells: versatile controllers of the immune system.

21 January 2018

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Occurrence of T cells in the brain of Alzheimer's disease and other neurological diseases.

21 January 2018

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Clinical relevance of specific T-cell activation in the blood and cerebrospinal fluid of patients with mild Alzheimer's disease.

21 January 2018

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HLA-DR-positive dendritic cells of the normal human choroid plexus: a potential reservoir of HIV in the central nervous system.

21 January 2018

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Two subsets of dendritic cells are present in human cerebrospinal fluid.

21 January 2018

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Macrophages and dendritic cells in the rat meninges and choroid plexus: three-dimensional localisation by environmental scanning electron microscopy and confocal microscopy

21 January 2018

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Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis.

21 January 2018

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Accumulation of resident and peripheral dendritic cells in the aging CNS

21 January 2018

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Selective ablation of bone marrow-derived dendritic cells increases amyloid plaques in a mouse Alzheimer's disease model.

21 January 2018

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Amyloid beta peptide promotes differentiation of pro-inflammatory human myeloid dendritic cells.

21 January 2018

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Increased pro-inflammatory response by dendritic cells from patients with Alzheimer's disease.

21 January 2018

1 reference

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The stimulation of dendritic cells by amyloid beta 1-42 reduces BDNF production in Alzheimer's disease patients.

21 January 2018

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Dendritic cells regulate amyloid-β-specific T-cell entry into the brain: the role of perivascular amyloid-β.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00632

Ineffective phagocytosis of amyloid-beta by macrophages of Alzheimer's disease patients.

21 January 2018

1 reference

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Mutant amyloid-beta-sensitized dendritic cells as Alzheimer's disease vaccine

28 November 2018

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