(Q26774441)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26690125%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

review article

0 references

title

Innate Immunity and Inflammation Post-Stroke: An α7-Nicotinic Agonist Perspective (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26690125%20AND%20SRC:MED&resulttype=core&format=json

alpha-7 nicotinic receptor

3 March 2020

main subject

inflammation

1 reference

PubMed publication ID

1 reference

15 December 2019

1 reference

31 July 2019

innate immune response

1 reference

PubMed publication ID

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26690125%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Andrew Clarkson

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26690125%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

author name string

Silke Neumann

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26690125%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Nicholas J Shields

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26690125%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Mary Chebib

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26690125%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

language of work or name

English

0 references

publication date

4 December 2015

8 references

19 March 2019

22 March 2019

25 April 2019

17 June 2019

31 July 2019

28 November 2019

15 December 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26690125%20AND%20SRC:MED&resulttype=core&format=json

International Journal of Molecular Sciences

3 March 2020

published in

8 references

19 March 2019

22 March 2019

25 April 2019

17 June 2019

31 July 2019

28 November 2019

15 December 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26690125%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

volume

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26690125%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26690125%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

page(s)

29029-29046

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26690125%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution

3 March 2020

copyright license

7 references

19 March 2019

22 March 2019

25 April 2019

17 June 2019

31 July 2019

28 November 2019

15 December 2019

0 references

on focus list of Wikimedia project

ScienceSource

0 references

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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DAMP signaling is a key pathway inducing immune modulation after brain injury.

28 September 2017

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The role of nucleotides and purinergic signaling in apoptotic cell clearance - implications for chronic inflammatory diseases

28 September 2017

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Diversity of native nicotinic receptor subtypes in mammalian brain

28 September 2017

1 reference

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Pro-inflammatory interferon gamma signaling is directly associated with stroke induced neurodegeneration

28 September 2017

1 reference

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Alpha-7 nicotinic acetylcholine receptor agonist treatment reduces neuroinflammation, oxidative stress, and brain injury in mice with ischemic stroke and bone fracture

28 September 2017

1 reference

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α7 nicotinic acetylcholine receptor signaling inhibits inflammasome activation by preventing mitochondrial DNA release

28 September 2017

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Beyond acetylcholinesterase inhibitors for treating Alzheimer's disease: α7-nAChR agonists in human clinical trials

28 September 2017

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Recombinant human interleukin-1 receptor antagonist in severe traumatic brain injury: a phase II randomized control trial.

28 September 2017

1 reference

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NLRP3 deficiency ameliorates neurovascular damage in experimental ischemic stroke

28 September 2017

1 reference

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The cholinergic anti-inflammatory pathway: a critical review

28 September 2017

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The effect of intravenous interleukin-1 receptor antagonist on inflammatory mediators in cerebrospinal fluid after subarachnoid haemorrhage: a phase II randomised controlled trial.

28 September 2017

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28 September 2017

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α7 nicotinic receptor agonist reactivates neurogenesis in adult brain.

28 September 2017

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How B cells capture, process and present antigens: a crucial role for cell polarity

28 September 2017

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Plasticity in the injured brain: more than molecules matter.

28 September 2017

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Adaptive immunity after cell death

28 September 2017

1 reference

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Influence of inflammation on poststroke plasticity

28 September 2017

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MFGE8 inhibits inflammasome-induced IL-1β production and limits postischemic cerebral injury

28 September 2017

1 reference

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Pharmacological inhibition of TLR4-NOX4 signal protects against neuronal death in transient focal ischemia

28 September 2017

1 reference

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Nicotinic acetylcholine receptors: from basic science to therapeutics

28 September 2017

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Adaptors in toll-like receptor signaling and their potential as therapeutic targets

28 September 2017

1 reference

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Nicotine-induced upregulation of native neuronal nicotinic receptors is caused by multiple mechanisms

28 September 2017

1 reference

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Cross-talk between myeloid-derived suppressor cells (MDSC), macrophages, and dendritic cells enhances tumor-induced immune suppression

28 September 2017

1 reference

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α7 nicotinic acetylcholine receptor agonist PNU-282987 attenuates early brain injury in a perforation model of subarachnoid hemorrhage in rats

28 September 2017

1 reference

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Characterization of the nature of granulocytic myeloid-derived suppressor cells in tumor-bearing mice

28 September 2017

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Global impairment and therapeutic restoration of visual plasticity mechanisms after a localized cortical stroke

28 September 2017

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A paradoxical role for myeloid-derived suppressor cells in sepsis and trauma

28 September 2017

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Inflammasomes: current understanding and open questions

28 September 2017

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Alpha7 nicotinic receptors as novel therapeutic targets for inflammation-based diseases

28 September 2017

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Acute ischemic stroke and infections

28 September 2017

1 reference

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High-mobility group box-1 protein promotes angiogenesis after peripheral ischemia in diabetic mice through a VEGF-dependent mechanism.

28 September 2017

1 reference

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Hierarchy of immunosuppressive strength among myeloid-derived suppressor cell subsets is determined by GM-CSF.

28 September 2017

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Prevalence, incidence, and factors associated with pre-stroke and post-stroke dementia: a systematic review and meta-analysis

28 September 2017

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Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance

28 September 2017

1 reference

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Mechanisms of neuroprotective effects of nicotine and acetylcholinesterase inhibitors: role of alpha4 and alpha7 receptors in neuroprotection

28 September 2017

1 reference

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ATP-gated P2X cation-channels

28 September 2017

1 reference

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Themes and strategies for studying the biology of stroke recovery in the poststroke epoch

28 September 2017

1 reference

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Infection after acute ischemic stroke: a manifestation of brain-induced immunodepression.

28 September 2017

1 reference

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CNS localization of neuronal nicotinic receptors.

28 September 2017

1 reference

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Mechanisms of immune suppression by interleukin-10 and transforming growth factor-beta: the role of T regulatory cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691088

Brain neuronal nicotinic receptors as new targets for drug discovery

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691088

Gene expression in blood changes rapidly in neutrophils and monocytes after ischemic stroke in humans: a microarray study

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691088

The vagus nerve and the nicotinic anti-inflammatory pathway

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691088

High mobility group box 1 protein, a cue for stem cell recruitment

28 September 2017

1 reference

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Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691088

Microglia, macrophages, perivascular macrophages, and pericytes: a review of function and identification

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691088

Complications following acute ischemic stroke

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691088

Mouse and human dendritic cell subtypes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691088

Role of IL-1alpha and IL-1beta in ischemic brain damage.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691088

Nicotinic cholinergic signaling in hippocampal astrocytes involves calcium-induced calcium release from intracellular stores

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691088

VEGF enhances angiogenesis and promotes blood-brain barrier leakage in the ischemic brain

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691088

The biochemistry and cell biology of antigen processing and presentation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691088

28 September 2017

Antigen presenting cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691088

A comparative study of stress-mediated immunological functions with the adjuvanticity of alum

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691088

α7 nicotinic acetylcholine receptor agonism confers neuroprotection through GSK-3β inhibition in a mouse model of intracerebral hemorrhage

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691088

Inhibition of reactive astrocytes with fluorocitrate retards neurovascular remodeling and recovery after focal cerebral ischemia in mice.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691088

The terminology issue for myeloid-derived suppressor cells

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691088

Interleukin-1 beta maturation and release in response to ATP and nigericin. Evidence that potassium depletion mediated by these agents is a necessary and common feature of their activity

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691088

Toll-like receptor 4 modulates cell migration and cortical neurogenesis after focal cerebral ischemia.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691088

Toll-like receptor 4 deficiency impairs microglial phagocytosis of degenerating axons.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691088

Proliferation of parenchymal microglia is the main source of microgliosis after ischaemic stroke

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691088

Nicotine prevents synaptic impairment induced by amyloid-β oligomers through α7-nicotinic acetylcholine receptor activation.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691088

Inflammasome-derived IL-1β production induces nitric oxide-mediated resistance to Leishmania

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691088

Toward a refined definition of monocyte subsets

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691088

Immunodeficiency reduces neural stem/progenitor cell apoptosis and enhances neurogenesis in the cerebral cortex after stroke

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691088

Cholinergic anti-inflammatory pathway in intracerebral hemorrhage

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691088

Recombinant C1 inhibitor in brain ischemic injury.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691088

Temporal and spatial dynamics of cerebral immune cell accumulation in stroke

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691088

Resident macrophages initiating and driving inflammation in a monosodium urate monohydrate crystal-induced murine peritoneal model of acute gout

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691088

Inhibition of the inflammasome complex reduces the inflammatory response after thromboembolic stroke in mice.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691088

Local self-renewal can sustain CNS microglia maintenance and function throughout adult life.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691088

High mobility group box 1 protein is released by neural cells upon different stresses and worsens ischemic neurodegeneration in vitro and in vivo

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691088

Anti-high mobility group box 1 monoclonal antibody ameliorates brain infarction induced by transient ischemia in rats

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691088

Toll-like receptor 4 is involved in brain damage and inflammation after experimental stroke.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691088

A neurovascular niche for neurogenesis after stroke.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691088

HMGB1, a novel cytokine-like mediator linking acute neuronal death and delayed neuroinflammation in the postischemic brain.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691088

Predominant phagocytic activity of resident microglia over hematogenous macrophages following transient focal cerebral ischemia: an investigation using green fluorescent protein transgenic bone marrow chimeric mice

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691088

Stimulation of the vagus nerve attenuates macrophage activation by activating the Jak2-STAT3 signaling pathway

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691088

Modulation of cerebral microvascular permeability by endothelial nicotinic acetylcholine receptors.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691088

Cholinergic agonists inhibit HMGB1 release and improve survival in experimental sepsis

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691088

Cholinergic modulation of microglial activation by alpha 7 nicotinic receptors

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691088

Presence of reactive microglia in monkey substantia nigra years after 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine administration

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691088

Microglial activation and tyrosine hydroxylase immunoreactivity in the substantia nigral region following transient focal ischemia in rats

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691088

IL-1 beta induces COX2, MMP-1, -3 and -13, ADAMTS-4, IL-1 beta and IL-6 in human tendon cells

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691088

Reduced ischemic brain injury in interleukin-1 beta converting enzyme-deficient mice

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691088

Stimulation of alpha7 nicotinic acetylcholine receptor inhibits CD14 and the toll-like receptor 4 expression in human monocytes

28 November 2018

1 reference

12 December 2020

NLR functions beyond pathogen recognition

1 reference

12 December 2020

TLR9 and the recognition of self and non-self nucleic acids

1 reference

12 December 2020

Expansion of myeloid immune suppressor Gr+CD11b+ cells in tumor-bearing host directly promotes tumor angiogenesis

1 reference

12 December 2020

Complexity and challenges in defining myeloid-derived suppressor cells

1 reference

12 December 2020

Interleukin-1 as a pathogenetic mediator of ischemic brain damage in rats

1 reference

12 December 2020

Experimental stroke induces massive, rapid activation of the peripheral immune system

1 reference

12 December 2020

Identifiers

DOI

10.3390/IJMS161226141

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26690125%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26690125%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

PubMed publication ID

26690125

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26690125%20AND%20SRC:MED&resulttype=core&format=json