(Q26777662)

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28 February 2020

1 reference

10 August 2020

Focal adhesions, stress fibers and mechanical tension (English)

1 reference

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28 February 2020

1 reference

10 August 2020

1 reference

1 reference

2

1 reference

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28 February 2020

author name string

Keith Burridge

series ordinal

1

1 reference

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28 February 2020

language of work or name

English

0 references

publication date

28 October 2015

1 reference

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Experimental Cell Research

28 February 2020

10 April 2016

1 reference

10 August 2020

3 references

12 October 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26519907%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

10 August 2020

343

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28 February 2020

page(s)

14-20

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28 February 2020

issue

1

1 reference

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Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International

28 February 2020

copyright license

2 references

12 October 2019

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

10 August 2020

cites work

1 reference

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Linear arrays of nuclear envelope proteins harness retrograde actin flow for nuclear movement.

7 April 2017

1 reference

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Stress fibers are generated by two distinct actin assembly mechanisms in motile cells

7 April 2017

1 reference

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Coupling of the nucleus and cytoplasm: role of the LINC complex

7 April 2017

1 reference

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Focal contacts as mechanosensors: externally applied local mechanical force induces growth of focal contacts by an mDia1-dependent and ROCK-independent mechanism

7 April 2017

1 reference

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p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin

7 April 2017

1 reference

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Rho-stimulated contractility drives the formation of stress fibers and focal adhesions

7 April 2017

1 reference

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Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)

7 April 2017

1 reference

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Fibroblasts, myofibroblasts, and wound contraction

7 April 2017

1 reference

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Myosin II-mediated focal adhesion maturation is tension insensitive

7 April 2017

1 reference

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Stretching actin filaments within cells enhances their affinity for the myosin II motor domain

7 April 2017

1 reference

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Reinforcement versus fluidization in cytoskeletal mechanoresponsiveness

7 April 2017

1 reference

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Comparative dynamics of retrograde actin flow and focal adhesions: formation of nascent adhesions triggers transition from fast to slow flow

7 April 2017

1 reference

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Matrix elasticity directs stem cell lineage specification

7 April 2017

1 reference

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Tensional homeostasis and the malignant phenotype

7 April 2017

1 reference

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Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

7 April 2017

1 reference

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The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

Nascent focal adhesions are responsible for the generation of strong propulsive forces in migrating fibroblasts

7 April 2017

1 reference

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Force fluctuations within focal adhesions mediate ECM-rigidity sensing to guide directed cell migration

7 April 2017

1 reference

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Spatiotemporal constraints on the force-dependent growth of focal adhesions

7 April 2017

1 reference

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Nuclear movement regulated by Cdc42, MRCK, myosin, and actin flow establishes MTOC polarization in migrating cells

7 April 2017

1 reference

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Activation of a signaling cascade by cytoskeleton stretch

7 April 2017

1 reference

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Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment

7 April 2017

1 reference

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Focal adhesions, contractility, and signaling

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

Myosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

Force activates smooth muscle alpha-actin promoter activity through the Rho signaling pathway

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase)

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

Actin cap associated focal adhesions and their distinct role in cellular mechanosensing

7 April 2017

1 reference

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Traction stress in focal adhesions correlates biphasically with actin retrograde flow speed

7 April 2017

1 reference

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Force Sensing by Mechanical Extension of the Src Family Kinase Substrate p130Cas

7 April 2017

1 reference

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Tissue cells feel and respond to the stiffness of their substrate

7 April 2017

1 reference

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Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics

7 April 2017

1 reference

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Stretching single talin rod molecules activates vinculin binding

7 April 2017

1 reference

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Actin and alpha-actinin orchestrate the assembly and maturation of nascent adhesions in a myosin II motor-independent manner

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

Two distinct actin networks drive the protrusion of migrating cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

FAK-Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

Cells lying on a bed of microneedles: an approach to isolate mechanical force

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

Force and focal adhesion assembly: a close relationship studied using elastic micropatterned substrates

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

Cell locomotion and focal adhesions are regulated by substrate flexibility

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

Integration of actin dynamics and cell adhesion by a three-dimensional, mechanosensitive molecular clutch.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

Tensional homeostasis in single fibroblasts

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

A contractile and counterbalancing adhesion system controls the 3D shape of crawling cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

Tight coupling between nucleus and cell migration through the perinuclear actin cap

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

Isolated nuclei adapt to force and reveal a mechanotransduction pathway in the nucleus.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

Emerin organizes actin flow for nuclear movement and centrosome orientation in migrating fibroblasts

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

Nuclear lamin-A scales with tissue stiffness and enhances matrix-directed differentiation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

Vinculin-actin interaction couples actin retrograde flow to focal adhesions, but is dispensable for focal adhesion growth.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

β1- and αv-class integrins cooperate to regulate myosin II during rigidity sensing of fibronectin-based microenvironments

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

The tension mounts: stress fibers as force-generating mechanotransducers

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

Microtubules regulate GEF-H1 in response to extracellular matrix stiffness

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

Tension is required but not sufficient for focal adhesion maturation without a stress fiber template

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

Adhesion dynamics at a glance

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

Actin filaments function as a tension sensor by tension-dependent binding of cofilin to the filament

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

Dynamic molecular processes mediate cellular mechanotransduction

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

The interaction between nesprins and sun proteins at the nuclear envelope is critical for force transmission between the nucleus and cytoskeleton

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

The Rho GEFs LARG and GEF-H1 regulate the mechanical response to force on integrins.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

Quantitative proteomics of the integrin adhesome show a myosin II-dependent recruitment of LIM domain proteins

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

Dynamic and structural signatures of lamellar actomyosin force generation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

A zyxin-mediated mechanism for actin stress fiber maintenance and repair

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

Interactions between nuclei and the cytoskeleton are mediated by SUN-KASH nuclear-envelope bridges.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

A perinuclear actin cap regulates nuclear shape.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

Demonstration of catch bonds between an integrin and its ligand.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

Mechanosensing in actin stress fibers revealed by a close correlation between force and protein localization

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

Mechanotransduction gone awry

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

Mechanically activated integrin switch controls alpha5beta1 function

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

Universal physical responses to stretch in the living cell

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

Forces and bond dynamics in cell adhesion.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

Regulation of protrusion, adhesion dynamics, and polarity by myosins IIA and IIB in migrating cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

Mechanical force mobilizes zyxin from focal adhesions to actin filaments and regulates cytoskeletal reinforcement

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

ROCK-generated contractility regulates breast epithelial cell differentiation in response to the physical properties of a three-dimensional collagen matrix

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

The relationship between force and focal complex development

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

Calculation of forces at focal adhesions from elastic substrate data: the effect of localized force and the need for regularization

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

Exploring the neighborhood: adhesion-coupled cell mechanosensors.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

Focal adhesion motility revealed in stationary fibroblasts

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

Self-polarization and directional motility of cytoplasm

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

Rho-mediated contractility exposes a cryptic site in fibronectin and induces fibronectin matrix assembly.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

Demonstration of mechanical connections between integrins, cytoskeletal filaments, and nucleoplasm that stabilize nuclear structure

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

Extracellular matrix rigidity causes strengthening of integrin-cytoskeleton linkages

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

Mechanotransduction across the cell surface and through the cytoskeleton

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

Relation between cell activity and the distribution of cytoplasmic actin and myosin

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

Preservation of normal behavior by enucleated cells in culture

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

A novel role for Lsc/p115 RhoGEF and LARG in regulating RhoA activity downstream of adhesion to fibronectin.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

Role of actin polymerization and adhesion to extracellular matrix in Rac- and Rho-induced cytoskeletal reorganization

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

Fibroblast contraction occurs on release of tension in attached collagen lattices: dependency on an organized actin cytoskeleton and serum

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

Myosin IIA regulates cell motility and actomyosin–microtubule crosstalk

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

Cellular adaptation to mechanical stress: role of integrins, Rho, cytoskeletal tension and mechanosensitive ion channels.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891215

Are stress fibres contractile?

28 November 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.10.029

Assembling an actin cytoskeleton for cell attachment and movement

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.10.029

Induction of human vascular endothelial stress fibres by fluid shear stress

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.10.029

Stress relaxation of contracted collagen gels: disruption of actin filament bundles, release of cell surface fibronectin, and down-regulation of DNA and protein synthesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2015.10.029

10.1016/J.YEXCR.2015.10.029

7 January 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26519907%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26519907%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26519907%20AND%20SRC:MED&resulttype=core&format=json