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Targeted Therapies in HER2-Positive Breast Cancer - a Systematic Review
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systematic review
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title
Targeted Therapies in HER2-Positive Breast Cancer - a Systematic Review
(English)
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main subject
Her2-receptor positive breast cancer
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systematic review
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inferred from title
author
Jens Huober
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5
object named as
Jens Huober
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author name string
Amelie Schramm
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1
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Nikolaus De Gregorio
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2
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Peter Widschwendter
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3
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Visnja Fink
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4
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language of work or name
English
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publication date
July 2015
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published in
Breast Care
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volume
10
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issue
3
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page(s)
173-8
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cites work
The HER2 Receptor in Breast Cancer: Pathophysiology, Clinical Use, and New Advances in Therapy
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PubMed Central
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Update on HER-2 as a target for cancer therapy: intracellular signaling pathways of ErbB2/HER-2 and family members
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Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer
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7 April 2017
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.
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7 April 2017
Pertuzumab, trastuzumab, and docetaxel in HER2-positive metastatic breast cancer
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7 April 2017
Phase II randomized study of trastuzumab emtansine versus trastuzumab plus docetaxel in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer
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7 April 2017
Trastuzumab emtansine for HER2-positive advanced breast cancer
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7 April 2017
Lapatinib with trastuzumab for HER2-positive early breast cancer (NeoALTTO): a randomised, open-label, multicentre, phase 3 trial
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7 April 2017
Recent advances in the development of anti-HER2 antibodies and antibody-drug conjugates
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7 April 2017
Efficacy and safety of neoadjuvant pertuzumab and trastuzumab in women with locally advanced, inflammatory, or early HER2-positive breast cancer (NeoSphere): a randomised multicentre, open-label, phase 2 trial
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7 April 2017
Trastuzumab--mechanism of action and use in clinical practice
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7 April 2017
Adjuvant paclitaxel and trastuzumab for node-negative, HER2-positive breast cancer
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28 September 2017
Trastuzumab plus adjuvant chemotherapy for human epidermal growth factor receptor 2-positive breast cancer: planned joint analysis of overall survival from NSABP B-31 and NCCTG N9831.
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28 September 2017
AGO Recommendations for the Diagnosis and Treatment of Patients with Advanced and Metastatic Breast Cancer: Update 2014.
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28 September 2017
AGO Recommendations for the Diagnosis and Treatment of Patients with Early Breast Cancer: Update 2014.
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28 September 2017
Current Approaches and Emerging Directions in HER2-resistant Breast Cancer
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28 September 2017
Pertuzumab for the treatment of breast cancer
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28 September 2017
Recommendations for human epidermal growth factor receptor 2 testing in breast cancer: American Society of Clinical Oncology/College of American Pathologists clinical practice guideline update
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28 September 2017
Sequential versus concurrent trastuzumab in adjuvant chemotherapy for breast cancer
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28 September 2017
Adjuvant trastuzumab in HER2-positive breast cancer
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PubMed Central
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28 September 2017
Four-year follow-up of trastuzumab plus adjuvant chemotherapy for operable human epidermal growth factor receptor 2-positive breast cancer: joint analysis of data from NCCTG N9831 and NSABP B-31.
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PubMed Central
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28 September 2017
Phase II trial of pertuzumab and trastuzumab in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer that progressed during prior trastuzumab therapy
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4569208
retrieved
28 September 2017
Strongly enhanced antitumor activity of trastuzumab and pertuzumab combination treatment on HER2-positive human xenograft tumor models
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PubMed Central
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28 September 2017
Understanding the mechanisms behind trastuzumab therapy for human epidermal growth factor receptor 2-positive breast cancer
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28 September 2017
Targeting HER2-positive breast cancer with trastuzumab-DM1, an antibody-cytotoxic drug conjugate
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PubMed Central
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28 September 2017
Trastuzumab: mechanism of action, resistance and future perspectives in HER2-overexpressing breast cancer.
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PubMed Central
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28 September 2017
Activity of the dual kinase inhibitor lapatinib (GW572016) against HER-2-overexpressing and trastuzumab-treated breast cancer cells
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4569208
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28 September 2017
The HER-2-targeting antibodies trastuzumab and pertuzumab synergistically inhibit the survival of breast cancer cells.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4569208
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28 September 2017
The effects of the novel, reversible epidermal growth factor receptor/ErbB-2 tyrosine kinase inhibitor, GW2016, on the growth of human normal and tumor-derived cell lines in vitro and in vivo.
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PubMed Central
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28 September 2017
Role of HER2 gene overexpression in breast carcinoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4569208
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28 September 2017
ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling
1 reference
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PubMed Central
reference URL
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28 September 2017
The biology of erbB-2/neu/HER-2 and its role in cancer
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4569208
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28 September 2017
Study of the biologic effects of lapatinib, a reversible inhibitor of ErbB1 and ErbB2 tyrosine kinases, on tumor growth and survival pathways in patients with advanced malignancies
1 reference
stated in
PubMed Central
reference URL
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31 May 2018
Perspectives from the American Society of Clinical Oncology 2014 Conference: breast cancer highlights
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4569208
retrieved
28 November 2018
2 years versus 1 year of adjuvant trastuzumab for HER2-positive breast cancer (HERA): an open-label, randomised controlled trial
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4569208
retrieved
28 November 2018
Lapatinib versus trastuzumab in combination with neoadjuvant anthracycline-taxane-based chemotherapy (GeparQuinto, GBG 44): a randomised phase 3 trial.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4569208
retrieved
28 November 2018
TGFalpha expression impairs Trastuzumab-induced HER2 downregulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4569208
retrieved
28 November 2018
Phase I clinical study of pertuzumab, a novel HER dimerization inhibitor, in patients with advanced cancer
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/26557822
retrieved
12 December 2020
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inferred from PubMed ID database lookup
Identifiers
DOI
10.1159/000431029
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4888153
OpenCitations bibliographic resource ID
4888153
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4888153
PMC publication ID
4569208
0 references
PubMed publication ID
26557822
0 references
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