(Q26781635)

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The past and the future of Alzheimer's disease CSF biomarkers-a journey toward validated biochemical tests covering the whole spectrum of molecular events

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scholarly article

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The past and the future of Alzheimer's disease CSF biomarkers-a journey toward validated biochemical tests covering the whole spectrum of molecular events (English)

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Alzheimer's disease

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inferred from title

1

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Henrik Zetterberg

2

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language of work or name

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publication date

2015

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Frontiers in Neuroscience

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9

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345

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Guidelines for the standardization of preanalytic variables for blood-based biomarker studies in Alzheimer's disease research

1 reference

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7 April 2017

Molecular machines governing exocytosis of synaptic vesicles

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7 April 2017

Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586276

7 April 2017

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586276

7 April 2017

Mild cognitive impairment: clinical characterization and outcome

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586276

7 April 2017

Aβ40 oligomers identified as a potential biomarker for the diagnosis of Alzheimer's disease

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586276

7 April 2017

The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

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7 April 2017

The diagnosis of mild cognitive impairment due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586276

7 April 2017

Research criteria for the diagnosis of Alzheimer's disease: revising the NINCDS-ADRDA criteria

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7 April 2017

Alzheimer's disease

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7 April 2017

Cerebrospinal fluid amyloid-β 42/40 ratio in clinical setting of memory centers: a multicentric study

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586276

28 September 2017

Amyloid biomarkers in Alzheimer's disease

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28 September 2017

SNAP-25 is a promising novel cerebrospinal fluid biomarker for synapse degeneration in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586276

28 September 2017

Diagnostic accuracy of CSF Ab42 and florbetapir PET for Alzheimer's disease

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586276

28 September 2017

Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria

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28 September 2017

The future of blood-based biomarkers for Alzheimer's disease

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586276

28 September 2017

Evaluating amyloid-β oligomers in cerebrospinal fluid as a biomarker for Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586276

28 September 2017

CSF biomarker variability in the Alzheimer's Association quality control program

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586276

28 September 2017

ApoE influences amyloid-β (Aβ) clearance despite minimal apoE/Aβ association in physiological conditions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586276

28 September 2017

Correlation of specific amyloid-β oligomers with tau in cerebrospinal fluid from cognitively normal older adults

1 reference

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28 September 2017

Injury markers predict time to dementia in subjects with MCI and amyloid pathology

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28 September 2017

Synaptic changes in Alzheimer's disease and its models

1 reference

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28 September 2017

Age and diagnostic performance of Alzheimer disease CSF biomarkers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586276

28 September 2017

Cerebrospinal fluid levels of β-amyloid 1-42, but not of tau, are fully changed already 5 to 10 years before the onset of Alzheimer dementia

1 reference

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28 September 2017

Amyloid imaging as a biomarker for cerebral β-amyloidosis and risk prediction for Alzheimer dementia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586276

28 September 2017

Human apoE isoforms differentially regulate brain amyloid-β peptide clearance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586276

28 September 2017

Soluble amyloid beta-protein dimers isolated from Alzheimer cortex directly induce Tau hyperphosphorylation and neuritic degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586276

28 September 2017

Cerebrospinal fluid biomarkers and rate of cognitive decline in very mild dementia of the Alzheimer type

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586276

28 September 2017

Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586276

28 September 2017

Thirty years of Alzheimer's disease genetics: the implications of systematic meta-analyses

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28 September 2017

Amyloid beta protein dimer-containing human CSF disrupts synaptic plasticity: prevention by systemic passive immunization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586276

28 September 2017

Prediction and longitudinal study of CSF biomarkers in mild cognitive impairment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586276

28 September 2017

Determination of beta-amyloid peptide signatures in cerebrospinal fluid using immunoprecipitation-mass spectrometry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586276

28 September 2017

Association between CSF biomarkers and incipient Alzheimer's disease in patients with mild cognitive impairment: a follow-up study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586276

28 September 2017

Nanoparticle-based detection in cerebral spinal fluid of a soluble pathogenic biomarker for Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586276

28 September 2017

Core biological marker candidates of Alzheimer's disease - perspectives for diagnosis, prediction of outcome and reflection of biological activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586276

28 September 2017

CSF markers for incipient Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586276

28 September 2017

Practice parameter: diagnosis of dementia (an evidence-based review). Report of the Quality Standards Subcommittee of the American Academy of Neurology

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28 September 2017

Targeting synaptic pathology with a novel affinity mass spectrometry approach

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586276

31 May 2018

CSF biomarkers and incipient Alzheimer disease in patients with mild cognitive impairment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586276

31 May 2018

Detection of single amyloid beta-protein aggregates in the cerebrospinal fluid of Alzheimer's patients by fluorescence correlation spectroscopy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586276

31 May 2018

Reduction of beta-amyloid peptide42 in the cerebrospinal fluid of patients with Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586276

31 May 2018

Alzheimer's presenile dementia, senile dementia of Alzheimer type and Down's syndrome in middle age form an age related continuum of pathological changes

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31 May 2018

Neocortical morphometry, lesion counts, and choline acetyltransferase levels in the age spectrum of Alzheimer's disease

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586276

31 May 2018

Synapse loss in frontal cortex biopsies in Alzheimer's disease: correlation with cognitive severity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586276

31 May 2018

Cerebrospinal fluid beta-amyloid(1-42) in Alzheimer disease: differences between early- and late-onset Alzheimer disease and stability during the course of disease.

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2015.00345

21 January 2018

Sensitivity, specificity, and stability of CSF-tau in AD in a community-based patient sample.

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2015.00345

21 January 2018

Biomarkers in Alzheimer's disease drug development.

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2015.00345

21 January 2018

Synaptic pathology in Alzheimer's disease: relation to severity of dementia, but not to senile plaques, neurofibrillary tangles, or the ApoE4 allele.

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2015.00345

21 January 2018

Tau protein in cerebrospinal fluid: a biochemical marker for axonal degeneration in Alzheimer disease?

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2015.00345

21 January 2018

Understanding biomarkers of neurodegeneration: Ultrasensitive detection techniques pave the way for mechanistic understanding.

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https://api.crossref.org/works/10.3389%2FFNINS.2015.00345

21 January 2018

Amyloid-β oligomer detection by ELISA in cerebrospinal fluid and brain tissue

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2015.00345

21 January 2018

Global standardization measurement of cerebral spinal fluid for Alzheimer's disease: an update from the Alzheimer's Association Global Biomarkers Consortium

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https://api.crossref.org/works/10.3389%2FFNINS.2015.00345

21 January 2018

Inverse relation between in vivo amyloid imaging load and cerebrospinal fluid Abeta42 in humans.

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2015.00345

21 January 2018

High-molecular-weight beta-amyloid oligomers are elevated in cerebrospinal fluid of Alzheimer patients

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2015.00345

21 January 2018

High cerebrospinal fluid tau and low amyloid beta42 levels in the clinical diagnosis of Alzheimer disease and relation to apolipoprotein E genotype.

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2015.00345

21 January 2018

Prediction of Alzheimer's disease using the CSF Abeta42/Abeta40 ratio in patients with mild cognitive impairment.

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2015.00345

21 January 2018

Neurogranin/RC3 enhances long-term potentiation and learning by promoting calcium-mediated signaling.

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2015.00345

21 January 2018

Improved discrimination of AD patients using beta-amyloid(1-42) and tau levels in CSF.

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2015.00345

21 January 2018

Amyloid-β oligomers relate to cognitive decline in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2015.00345

21 January 2018

Cerebrospinal fluid levels of the synaptic protein neurogranin correlates with cognitive decline in prodromal Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2015.00345

21 January 2018

Apolipoprotein E genotype and the diagnostic accuracy of cerebrospinal fluid biomarkers for Alzheimer disease

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2015.00345

21 January 2018

Amyloid-β 42/40 cerebrospinal fluid concentration ratio in the diagnostics of Alzheimer's disease: validation of two novel assays.

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2015.00345

21 January 2018

CSF tau/Abeta42 ratio for increased risk of mild cognitive impairment: a follow-up study

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2015.00345

21 January 2018

Altered expression of synaptic proteins occurs early during progression of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2015.00345

21 January 2018

Cortical neuronal counts in normal elderly controls and demented patients.

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2015.00345

21 January 2018

APOE epsilon4 allele is associated with reduced cerebrospinal fluid levels of Abeta42.

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2015.00345

21 January 2018

Changes in plasma amyloid beta in a longitudinal study of aging and Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2015.00345

21 January 2018

The load of amyloid-β oligomers is decreased in the cerebrospinal fluid of Alzheimer's disease patients.

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2015.00345

21 January 2018

Amyloid-β oligomers in cerebrospinal fluid are associated with cognitive decline in patients with Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2015.00345

21 January 2018

A sensitive aβ oligomer assay discriminates Alzheimer's and aged control cerebrospinal fluid.

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2015.00345

21 January 2018

Synaptic alterations in CA1 in mild Alzheimer disease and mild cognitive impairment.

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2015.00345

21 January 2018

Neurogranin in cerebrospinal fluid as a marker of synaptic degeneration in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2015.00345

21 January 2018

Prevalence and prognostic value of CSF markers of Alzheimer's disease pathology in patients with subjective cognitive impairment or mild cognitive impairment in the DESCRIPA study: a prospective cohort study.

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2015.00345

21 January 2018

Comparison of International Working Group criteria and National Institute on Aging-Alzheimer's Association criteria for Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2015.00345

21 January 2018

Attenuation of protein kinase C and cAMP-dependent protein kinase signal transduction in the neurogranin knockout mouse.

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2015.00345

21 January 2018

A candidate plasma protein classifier to identify Alzheimer's disease

1 reference

https://api.crossref.org/works/10.3389%2FFNINS.2015.00345

21 January 2018

Differential loss of synaptic proteins in Alzheimer's disease: implications for synaptic dysfunction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586276

28 November 2018

Neurochemical dissection of synaptic pathology in Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586276

28 November 2018

Loss of the presynaptic vesicle protein synaptophysin in hippocampus correlates with cognitive decline in Alzheimer disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4586276

28 November 2018

Clinical Chemistry and Laboratory Medicine: an appreciation

1 reference

https://pubmed.ncbi.nlm.nih.gov/26483625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cerebrospinal fluid tau and Abeta42 as predictors of development of Alzheimer's disease in patients with mild cognitive impairment

1 reference

https://pubmed.ncbi.nlm.nih.gov/26483625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3389/FNINS.2015.00345

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

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