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The cybernetics of TNF: Old views and newer ones
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scholarly article
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title
The cybernetics of TNF: Old views and newer ones
(English)
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main subject
TNF
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author name string
David Wallach
series ordinal
1
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language of work or name
English
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publication date
February 2016
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published in
Seminars in Cell & Developmental Biology
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volume
50
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page(s)
105-14
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cites work
Systemic anti-tumor necrosis factor α therapy in rheumatoid arthritis down-regulates synovial tumor necrosis factor α synthesis
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Rheumatoid arthritis is a heterogeneous disease: evidence for differences in the activation of the STAT-1 pathway between rheumatoid tissues
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Detection of tumor necrosis factor alpha but not tumor necrosis factor beta in rheumatoid arthritis synovial fluid and serum
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Increased levels of soluble tumor necrosis factor receptors in the sera and synovial fluid of patients with rheumatic diseases
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Tumor necrosis factor α induces sustained signaling and a prolonged and unremitting inflammatory response in rheumatoid arthritis synovial fibroblasts
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Prolonged tumor necrosis factor α primes fibroblast-like synoviocytes in a gene-specific manner by altering chromatin.
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Interleukin-12 is required for interferon-gamma production and lethality in lipopolysaccharide-induced shock in mice.
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Cytokine stimulation of T lymphocytes regulates their capacity to induce monocyte production of tumor necrosis factor-alpha, but not interleukin-10: possible relevance to pathophysiology of rheumatoid arthritis
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Early endothelium activation and polymorphonuclear cell invasion precede specific necrosis of human melanoma and sarcoma treated by intravascular high-dose tumour necrosis factor alpha (rTNF alpha)
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Macroscopic and microscopic early effects of tumour necrosis factor on murine Meth A sarcoma, and relation to curative activity
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TNF-mediated inflammatory disease.
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Involvement of 26-kDa membrane-bound tumour necrosis factor precursor in bidirectional feedback regulation on 17-kDa tumour necrosis factor production after stimulation by lipopolysaccharide
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LPS pretreatment protects from hepatic ischemia/reperfusion
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Necrotizing activity of tumor necrosis factor: histopathological investigation using Meth A sarcoma and granulation tissue
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Endotoxin tolerance-mechanisms and beneficial effects in bacterial infection
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Treatment of Crohn's disease with anti-tumor necrosis factor chimeric monoclonal antibody (cA2).
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A novel form of TNF/cachectin is a cell surface cytotoxic transmembrane protein: ramifications for the complex physiology of TNF
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The precursor of NF-kappa B p50 has I kappa B-like functions
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Tumour necrosis factor alpha in stool as a marker of intestinal inflammation
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Binding of human TNF-alpha to high-affinity cell surface receptors: effect of IFN.
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Infusion of tumor necrosis factor (TNF) causes an increase in circulating TNF-binding protein in humans
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A phase III study of infliximab and corticosteroids for the initial treatment of acute graft-versus-host disease
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A fourth IkappaB protein within the NF-kappaB signaling module
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TNFR1 signaling kinetics: spatiotemporal control of three phases of IKK activation by posttranslational modification
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Quantitative dissection and modeling of the NF-κB p100-p105 module reveals interdependent precursor proteolysis.
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Ubiquitination of RIP1 regulates an NF-kappaB-independent cell-death switch in TNF signaling
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Ligands working as receptors: reverse signaling by members of the TNF superfamily enhance the plasticity of the immune system
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Signal integration between IFNgamma and TLR signalling pathways in macrophages
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Endotoxin tolerance: new mechanisms, molecules and clinical significance
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Dissecting negative regulation of Toll-like receptor signaling
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The Nfkb1 and Nfkb2 proteins p105 and p100 function as the core of high-molecular-weight heterogeneous complexes
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cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms
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TNF and MAP kinase signalling pathways
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Diverse ubiquitin signaling in NF-κB activation
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Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes
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PROPHYLACTIC INOCULATION AGAINST HAY FEVER
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FURTHER OBSERVATIONS ON THE TREATMENT OF HAY FEVER BY HYPODERMIC INOCULATIONS OF POLLEN VACCINE
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Interrelated effects of tumor necrosis factor and interleukin 1 on cell viability
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based on heuristic
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Tumor necrosis factor has positive and negative self regulatory feed back cycles centered around cAMP.
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Death-inducing functions of ligands of the tumor necrosis factor family: a Sanhedrin verdict
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Modulation of NF-kappaB activity by exchange of dimers.
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Stimulation of bone resorption and inhibition of bone formation in vitro by human tumour necrosis factors.
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Tumour necrosis factor α stimulates resorption and inhibits synthesis of proteoglycan in cartilage
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A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells
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Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule
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MicroRNA in TLR signaling and endotoxin tolerance.
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Phosphorylation of NF-kappaB p65 at Ser468 controls its COMMD1-dependent ubiquitination and target gene-specific proteasomal elimination
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Regulation of TNF-α with a focus on rheumatoid arthritis
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SPPL2a and SPPL2b promote intramembrane proteolysis of TNFalpha in activated dendritic cells to trigger IL-12 production
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PDLIM2-mediated termination of transcription factor NF-kappaB activation by intranuclear sequestration and degradation of the p65 subunit
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7 January 2021
based on heuristic
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TNF activates an IRF1-dependent autocrine loop leading to sustained expression of chemokines and STAT1-dependent type I interferon–response genes
1 reference
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7 January 2021
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The stability of mRNA influences the temporal order of the induction of genes encoding inflammatory molecules
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Tumor necrosis factor induces GSK3 kinase-mediated cross-tolerance to endotoxin in macrophages
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Return to homeostasis: downregulation of NF-κB responses
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Short-term memory of danger signals and environmental stimuli in immune cells
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Interleukin-15 mediates T cell-dependent regulation of tumor necrosis factor-α production in rheumatoid arthritis
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7 January 2021
based on heuristic
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Evidence for the involvement of endothelial cell integrin alphaVbeta3 in the disruption of the tumor vasculature induced by TNF and IFN-gamma
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7 January 2021
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The immunology of stroke: from mechanisms to translation
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7 January 2021
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Toll-like receptor signalling
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Concepts of tissue injury and cell death in inflammation: a historical perspective
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7 January 2021
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Tumor necrosis factor signaling.
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7 January 2021
based on heuristic
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Role of JNK activation in apoptosis: a double-edged sword
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7 January 2021
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TNFR1 upregulation mediates tolerance after brain ischemic preconditioning.
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7 January 2021
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inferred from DOI database lookup
Protein kinase networks that limit TLR signalling
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7 January 2021
based on heuristic
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NF-kappaB stimulates inducible nitric oxide synthase to protect mouse hepatocytes from TNF-alpha- and Fas-mediated apoptosis
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Shwartzman reaction
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7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of coagulation after administration of tumor necrosis factor to normal subjects
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7 January 2021
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The pathogenesis of rheumatoid arthritis
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7 January 2021
based on heuristic
inferred from DOI database lookup
IFN-γ abrogates endotoxin tolerance by facilitating Toll-like receptor-induced chromatin remodeling
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cytokine-dependent but acquired immunity-independent arthritis caused by DNA escaped from degradation
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7 January 2021
based on heuristic
inferred from DOI database lookup
RNA splicing regulates the temporal order of TNF-induced gene expression
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https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2015.10.014
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7 January 2021
based on heuristic
inferred from DOI database lookup
An endotoxin-induced serum factor that causes necrosis of tumors
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7 January 2021
based on heuristic
inferred from DOI database lookup
Galactosamine-induced sensitization to the lethal effects of endotoxin
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7 January 2021
based on heuristic
inferred from DOI database lookup
Use of monoclonal antibodies to a human cytotoxin for its isolation and for examining the self-induction of resistance to this protein
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7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor necrosis factor: specific binding and internalization in sensitive and resistant cells
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7 January 2021
based on heuristic
inferred from DOI database lookup
Synergy between tumor necrosis factor and bacterial products causes hemorrhagic necrosis and lethal shock in normal mice
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7 January 2021
based on heuristic
inferred from DOI database lookup
Synergy between interferon-gamma and tumor necrosis factor-alpha in transcriptional activation is mediated by cooperation between signal transducer and activator of transcription 1 and nuclear factor kappaB.
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https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2015.10.014
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7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor necrosis factor-alpha inversely regulates prostaglandin D2 and prostaglandin E2 production in murine macrophages. Synergistic action of cyclic AMP on cyclooxygenase-2 expression and prostaglandin E2 synthesis
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7 January 2021
based on heuristic
inferred from DOI database lookup
Nitric oxide suppresses apoptosis via interrupting caspase activation and mitochondrial dysfunction in cultured hepatocytes
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https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2015.10.014
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7 January 2021
based on heuristic
inferred from DOI database lookup
Persistent tumor necrosis factor signaling in normal human fibroblasts prevents the complete resynthesis of I kappa B-alpha
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7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase-mediated cleavage converts the tumor necrosis factor (TNF) receptor-associated factor (TRAF)-1 from a selective modulator of TNF receptor signaling to a general inhibitor of NF-kappaB activation
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7 January 2021
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COMMD proteins, a novel family of structural and functional homologs of MURR1
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7 January 2021
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inferred from DOI database lookup
Cytotoxicity mediated by soluble antigen and lymphocytes in delayed hypersensitivity. 3. Analysis of mechanism
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7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor necrosis factor/cachectin. Induction of hemorrhagic necrosis in normal tissue requires the fifth component of complement (C5).
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7 January 2021
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inferred from DOI database lookup
Stabilization of the bioactivity of tumor necrosis factor by its soluble receptors
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mice that lack the interferon-gamma receptor have profoundly altered responses to infection with Bacillus Calmette-Guérin and subsequent challenge with lipopolysaccharide.
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7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor necrosis factor (TNF) receptor shedding controls thresholds of innate immune activation that balance opposing TNF functions in infectious and inflammatory diseases
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2015.10.014
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7 January 2021
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Mesenchymal cell targeting by TNF as a common pathogenic principle in chronic inflammatory joint and intestinal diseases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2015.10.014
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7 January 2021
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TNF suppresses acute intestinal inflammation by inducing local glucocorticoid synthesis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2015.10.014
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7 January 2021
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Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2015.10.014
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7 January 2021
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NF-κB, the first quarter-century: remarkable progress and outstanding questions
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2015.10.014
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7 January 2021
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Elevated tumour necrosis factor-alpha (TNF-alpha) biological activity in psoriatic skin lesions
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2015.10.014
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7 January 2021
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The IkappaB-NF-kappaB signaling module: temporal control and selective gene activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2015.10.014
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7 January 2021
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Oscillations in NF-kappaB signaling control the dynamics of gene expression
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2015.10.014
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7 January 2021
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Activity of protein kinase RIPK3 determines whether cells die by necroptosis or apoptosis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2015.10.014
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7 January 2021
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Prevention of constitutive TNF receptor 1 signaling by silencer of death domains
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2015.10.014
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7 January 2021
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Positive and negative regulation of IkappaB kinase activity through IKKbeta subunit phosphorylation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2015.10.014
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7 January 2021
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Fas-induced caspase denitrosylation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2015.10.014
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7 January 2021
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Shock and tissue injury induced by recombinant human cachectin
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2015.10.014
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7 January 2021
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Passive immunization against cachectin/tumor necrosis factor protects mice from lethal effect of endotoxin
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2015.10.014
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7 January 2021
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Negative feedback in noncanonical NF-kappaB signaling modulates NIK stability through IKKalpha-mediated phosphorylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2015.10.014
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7 January 2021
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Induction of tolerance to lipopolysaccharide (LPS)-D-galactosamine lethality by pretreatment with LPS is mediated by macrophages.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2015.10.014
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7 January 2021
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Beta interferon subtype 1 induction by tumor necrosis factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2015.10.014
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7 January 2021
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Tumour necrosis factor in synovial exudates
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2015.10.014
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7 January 2021
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Detection of mRNAs for macrophage products in inflammatory bowel disease by in situ hybridisation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2015.10.014
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7 January 2021
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Location of tumour necrosis factor alpha by immunohistochemistry in chronic inflammatory bowel disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2015.10.014
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7 January 2021
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Regulated cell death: signaling and mechanisms
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2015.10.014
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7 January 2021
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Tumor necrosis factor receptor and Fas signaling mechanisms.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2015.10.014
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7 January 2021
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Toll-like receptor (TLR4) shedding and depletion: acute proximal tubular cell responses to hypoxic and toxic injury
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2015.10.014
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7 January 2021
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Regulation of the hypothalamic-pituitary-adrenal axis by cytokines: actions and mechanisms of action
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2015.10.014
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7 January 2021
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Caspase-mediated p65 cleavage promotes TRAIL-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2015.10.014
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7 January 2021
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Endogenous tumor necrosis factor functions as a resistant factor against hyperthermic cytotoxicity in pancreatic carcinoma cells via enhancement of the heart shock element-binding activity of heart shock factor 1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2015.10.014
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7 January 2021
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Type I interferon: a new player in TNF signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2015.10.014
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7 January 2021
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The first decade of biologic TNF antagonists in clinical practice: lessons learned, unresolved issues and future directions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2015.10.014
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7 January 2021
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Shedding kinetics of soluble tumor necrosis factor (TNF) receptors after systemic TNF leaking during isolated limb perfusion. Relevance to the pathophysiology of septic shock.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2015.10.014
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7 January 2021
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TLR-signaling networks: an integration of adaptor molecules, kinases, and cross-talk.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2015.10.014
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7 January 2021
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Generation and physiological roles of linear ubiquitin chains
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2015.10.014
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7 January 2021
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Role of p52 (NF-kappaB2) in LPS tolerance in a human B cell line
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2015.10.014
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7 January 2021
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Cutting edge: TNF-induced microRNAs regulate TNF-induced expression of E-selectin and intercellular adhesion molecule-1 on human endothelial cells: feedback control of inflammation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2015.10.014
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7 January 2021
based on heuristic
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Cutting edge: endotoxin tolerance in mouse peritoneal macrophages correlates with down-regulation of surface toll-like receptor 4 expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2015.10.014
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7 January 2021
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A mammalian pseudogene lncRNA at the interface of inflammation and anti-inflammatory therapeutics
1 reference
stated in
Crossref
reference URL
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7 January 2021
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Identifiers
DOI
10.1016/J.SEMCDB.2015.10.014
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4475099
OpenCitations bibliographic resource ID
4475099
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4475099
PubMed publication ID
26474540
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4475099
ResearchGate publication ID
282944465
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