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Human Cancer Immunotherapy with PD-1/PD-L1 Blockade
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scholarly article
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title
Human Cancer Immunotherapy with PD-1/PD-L1 Blockade
(English)
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main subject
immunotherapy
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based on heuristic
inferred from title
author
Peilin Zheng
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
4578571
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26448693%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 June 2020
author name string
Zhiguang Zhou
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
4578571
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26448693%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 June 2020
language of work or name
English
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publication date
2015
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published in
Biomarkers in cancer
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stated in
Crossref
stated in
Europe PubMed Central
PMC publication ID
4578571
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26448693%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 June 2020
volume
7
1 reference
stated in
Europe PubMed Central
PMC publication ID
4578571
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26448693%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 June 2020
issue
Suppl 2
1 reference
stated in
Europe PubMed Central
PMC publication ID
4578571
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26448693%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 June 2020
page(s)
15-18
1 reference
stated in
Europe PubMed Central
PMC publication ID
4578571
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26448693%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 June 2020
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PD-1/SHP-2 inhibits Tc1/Th1 phenotypic responses and the activation of T cells in the tumor microenvironment
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Expression of programmed death ligand 1 (PD-L1) is associated with poor prognosis in human breast cancer
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Programmed death ligand-1 over-expression correlates with malignancy and contributes to immune regulation in ovarian cancer
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The presence of programmed death 1 (PD-1)-positive tumor-infiltrating lymphocytes is associated with poor prognosis in human breast cancer.
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Programmed death-1 upregulation is correlated with dysfunction of tumor-infiltrating CD8+ T lymphocytes in human non-small cell lung cancer
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28 September 2017
Tumor-infiltrating NY-ESO-1-specific CD8+ T cells are negatively regulated by LAG-3 and PD-1 in human ovarian cancer
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reference URL
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28 September 2017
Tumor antigen-specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4578571
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28 September 2017
Overexpression of PD-L1 significantly associates with tumor aggressiveness and postoperative recurrence in human hepatocellular carcinoma
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4578571
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28 September 2017
Phase I safety and pharmacokinetic study of CT-011, a humanized antibody interacting with PD-1, in patients with advanced hematologic malignancies
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4578571
retrieved
28 September 2017
Programmed death-1 ligand 1 interacts specifically with the B7-1 costimulatory molecule to inhibit T cell responses
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4578571
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28 September 2017
The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4578571
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28 September 2017
Blockade of B7-H1 and PD-1 by monoclonal antibodies potentiates cancer therapeutic immunity
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4578571
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28 September 2017
PD-1 blockade inhibits hematogenous spread of poorly immunogenic tumor cells by enhanced recruitment of effector T cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4578571
retrieved
28 September 2017
PD-1 inhibits T-cell receptor induced phosphorylation of the ZAP70/CD3zeta signalosome and downstream signaling to PKCtheta
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4578571
retrieved
28 September 2017
PD-L1-deficient mice show that PD-L1 on T cells, antigen-presenting cells, and host tissues negatively regulates T cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4578571
retrieved
28 September 2017
SHP-1 and SHP-2 associate with immunoreceptor tyrosine-based switch motif of programmed death 1 upon primary human T cell stimulation, but only receptor ligation prevents T cell activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4578571
retrieved
28 September 2017
Association of PD-L1 overexpression with activating EGFR mutations in surgically resected nonsmall-cell lung cancer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4578571
retrieved
31 May 2018
6th Annual European Antibody Congress 2010: November 29-December 1, 2010, Geneva, Switzerland
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4578571
retrieved
31 May 2018
PD-1 and PD-L1 upregulation promotes CD8(+) T-cell apoptosis and postoperative recurrence in hepatocellular carcinoma patients.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4578571
retrieved
28 November 2018
Tumor cell expression of programmed cell death-1 ligand 1 is a prognostic factor for malignant melanoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4578571
retrieved
28 November 2018
Programmed death-1 blockade enhances expansion and functional capacity of human melanoma antigen-specific CTLs.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4578571
retrieved
28 November 2018
Clinical significance and therapeutic potential of the programmed death-1 ligand/programmed death-1 pathway in human pancreatic cancer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4578571
retrieved
28 November 2018
Progressive upregulation of PD-1 in primary and metastatic melanomas associated with blunted TCR signaling in infiltrating T lymphocytes
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/26448693
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
PD-1(+) immune cell infiltration inversely correlates with survival of operable breast cancer patients
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/26448693
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
PD-L2 is predominantly expressed by Th2 cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/26448693
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
B7-DC-Ig enhances vaccine effect by a novel mechanism dependent on PD-1 expression level on T cell subsets
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/26448693
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.4137/BIC.S29325
1 reference
stated in
Europe PubMed Central
PMC publication ID
4578571
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26448693%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 June 2020
PMC publication ID
4578571
1 reference
stated in
Europe PubMed Central
PMC publication ID
4578571
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26448693%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 June 2020
PubMed publication ID
26448693
1 reference
stated in
Europe PubMed Central
PMC publication ID
4578571
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26448693%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 June 2020
ResearchGate publication ID
282760717
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