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Therapy escape mechanisms in the malignant prostate
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1 reference
stated in
Europe PubMed Central
PubMed ID
26299608
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26299608%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 February 2020
title
Therapy escape mechanisms in the malignant prostate
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
26299608
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26299608%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 February 2020
author
Frédéric R Santer
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
26299608
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26299608%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 February 2020
Holger H H Erb
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
26299608
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26299608%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 February 2020
author name string
Rhiannon V McNeill
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed ID
26299608
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26299608%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 February 2020
language of work or name
English
0 references
publication date
21 August 2015
1 reference
stated in
Europe PubMed Central
PubMed ID
26299608
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26299608%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 February 2020
published in
Seminars in Cancer Biology
1 reference
stated in
Europe PubMed Central
PubMed ID
26299608
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26299608%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 February 2020
volume
35
1 reference
stated in
Europe PubMed Central
PubMed ID
26299608
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26299608%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 February 2020
page(s)
133-144
1 reference
stated in
Europe PubMed Central
PubMed ID
26299608
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26299608%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 February 2020
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Selective expression of CD44, a putative prostate cancer stem cell marker, in neuroendocrine tumor cells of human prostate cancer
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7 January 2021
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Human ASH-1 promotes neuroendocrine differentiation in androgen deprivation conditions and interferes with androgen responsiveness in prostate cancer cells.
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https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
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7 January 2021
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Interleukin-6 induces neuroendocrine differentiation (NED) through suppression of RE-1 silencing transcription factor (REST).
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https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
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7 January 2021
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Androgen receptor splice variants contribute to prostate cancer aggressiveness through induction of EMT and expression of stem cell marker genes
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Three predominant proteins secreted by the human prostate gland
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Circulating levels of interleukin-6 in patients with hormone refractory prostate cancer
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7 January 2021
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Androgen receptor co-activators in the regulation of cellular events in prostate cancer.
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https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
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7 January 2021
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inferred from DOI database lookup
AR-Q640X, a model to study the effects of constitutively active C-terminally truncated AR variants in prostate cancer cells
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https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
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7 January 2021
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Oxygen free radicals and metallothionein
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https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
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7 January 2021
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Altered corepressor SMRT expression and recruitment to target genes as a mechanism that change the response to androgens in prostate cancer progression
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7 January 2021
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Regulation of androgen receptor activity by tyrosine phosphorylation.
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https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cell autonomous role of PTEN in regulating castration-resistant prostate cancer growth
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https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
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7 January 2021
based on heuristic
inferred from DOI database lookup
Androgen receptor gene expression in prostate cancer is directly suppressed by the androgen receptor through recruitment of lysine-specific demethylase 1.
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
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7 January 2021
based on heuristic
inferred from DOI database lookup
The E3 ubiquitin ligase Siah2 contributes to castration-resistant prostate cancer by regulation of androgen receptor transcriptional activity
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Crossref
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https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
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7 January 2021
based on heuristic
inferred from DOI database lookup
A gain-of-function mutation in DHT synthesis in castration-resistant prostate cancer
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
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7 January 2021
based on heuristic
inferred from DOI database lookup
Glucocorticoid receptor confers resistance to antiandrogens by bypassing androgen receptor blockade
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https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
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7 January 2021
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inferred from DOI database lookup
Androgen dependent regulation of protein kinase A subunits in prostate cancer cells
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https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
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7 January 2021
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inferred from DOI database lookup
Roles of cAMP and cAMP-dependent protein kinase in the progression of prostate cancer: cross-talk with the androgen receptor
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https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
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7 January 2021
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inferred from DOI database lookup
Protein kinase A-mediated phosphorylation of RhoA on serine 188 triggers the rapid induction of a neuroendocrine-like phenotype in prostate cancer epithelial cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
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7 January 2021
based on heuristic
inferred from DOI database lookup
Destruction of full-length androgen receptor by wild-type SPOP, but not prostate-cancer-associated mutants
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Crossref
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https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
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7 January 2021
based on heuristic
inferred from DOI database lookup
Neuroendocrine differentiation in hormone refractory prostate cancer following androgen deprivation therapy
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
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7 January 2021
based on heuristic
inferred from DOI database lookup
Skewing towards neuroendocrine phenotype in high grade or high stage androgen-responsive primary prostate cancer
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Crossref
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7 January 2021
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inferred from DOI database lookup
TMPRSS2-ERG status in circulating tumor cells as a predictive biomarker of sensitivity in castration-resistant prostate cancer patients treated with abiraterone acetate
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
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7 January 2021
based on heuristic
inferred from DOI database lookup
EAU guidelines on prostate cancer. Part II: Treatment of advanced, relapsing, and castration-resistant prostate cancer.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
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7 January 2021
based on heuristic
inferred from DOI database lookup
MicroRNA Expression Profile of Primary Prostate Cancer Stem Cells as a Source of Biomarkers and Therapeutic Targets
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PTEN protein loss and clinical outcome from castration-resistant prostate cancer treated with abiraterone acetate.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prostate cancer stem cells: are they androgen-responsive?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Fer tyrosine kinase acts as a downstream interleukin-6 effector of androgen receptor activation in prostate cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The PSA(-/lo) prostate cancer cell population harbors self-renewing long-term tumor-propagating cells that resist castration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
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7 January 2021
based on heuristic
inferred from DOI database lookup
Metallothioneins and resistance to cisplatin and radiation in prostate cancer.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Insulin-like growth factor pathway: a link between androgen deprivation therapy (ADT), insulin resistance, and disease progression in patients with prostate cancer?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
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7 January 2021
based on heuristic
inferred from DOI database lookup
Prostate stem cell compartments: expression of the cell cycle inhibitor p27Kip1 in normal, hyperplastic, and neoplastic cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin-6 differentially regulates androgen receptor transactivation via PI3K-Akt, STAT3, and MAPK, three distinct signal pathways in prostate cancer cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
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7 January 2021
based on heuristic
inferred from DOI database lookup
ANDROGEN RECEPTOR GENE AMPLIFICATION AT PRIMARY PROGRESSION PREDICTS RESPONSE TO COMBINED ANDROGEN BLOCKADE AS SECOND LINE THERAPY FOR ADVANCED PROSTATE CANCER
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https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
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7 January 2021
based on heuristic
inferred from DOI database lookup
Abiraterone acetate for treatment of metastatic castration-resistant prostate cancer: final overall survival analysis of the COU-AA-301 randomised, double-blind, placebo-controlled phase 3 study
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
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7 January 2021
based on heuristic
inferred from DOI database lookup
Androgen deprivation therapy plus docetaxel and estramustine versus androgen deprivation therapy alone for high-risk localised prostate cancer (GETUG 12): a phase 3 randomised controlled trial
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
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7 January 2021
based on heuristic
inferred from DOI database lookup
Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
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7 January 2021
based on heuristic
inferred from DOI database lookup
Src family kinases in tumor progression and metastasis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
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7 January 2021
based on heuristic
inferred from DOI database lookup
Glucocorticoids can promote androgen-independent growth of prostate cancer cells through a mutated androgen receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HDAC inhibitor confers radiosensitivity to prostate stem-like cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
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7 January 2021
based on heuristic
inferred from DOI database lookup
Focal amplification of the androgen receptor gene in hormone-naive human prostate cancer.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The polycomb group protein EZH2 is involved in progression of prostate cancer
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
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7 January 2021
based on heuristic
inferred from DOI database lookup
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The mutational landscape of lethal castration-resistant prostate cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Monoallelic expression of TMPRSS2/ERG in prostate cancer stem cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cancer stem cells in solid tumours: accumulating evidence and unresolved questions
1 reference
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https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
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7 January 2021
based on heuristic
inferred from DOI database lookup
Advanced prostate cancer--a case for adjuvant differentiation therapy.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
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7 January 2021
based on heuristic
inferred from DOI database lookup
Zinc and zinc transporters in prostate carcinogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Are androgen receptor variants a substitute for the full-length receptor?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Overexpression of androgen receptor enhances the binding of the receptor to the chromatin in prostate cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
AR intragenic deletions linked to androgen receptor splice variant expression and activity in models of prostate cancer progression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanisms of the androgen receptor splicing in prostate cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SOX2 expression in the developing, adult, as well as, diseased prostate
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Beyond tumorigenesis: cancer stem cells in metastasis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of PTEN and the 10q23 region in primary prostate carcinomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Receptor protein tyrosine phosphatase alpha signaling is involved in androgen depletion-induced neuroendocrine differentiation of androgen-sensitive LNCaP human prostate cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of p300 histone acetyltransferase activity and acetylation of the androgen receptor by bombesin in prostate cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Highly purified CD44+ prostate cancer cells from xenograft human tumors are enriched in tumorigenic and metastatic progenitor cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Constitutively active AR-V7 plays an essential role in the development and progression of castration-resistant prostate cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The anti-apoptotic genes Bcl-X(L) and Bcl-2 are over-expressed and contribute to chemoresistance of non-proliferating leukaemic CD34+ cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stem cell differentiation within the human prostate epithelium: implications for prostate carcinogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased survival with enzalutamide in prostate cancer after chemotherapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
AR-V7 and resistance to enzalutamide and abiraterone in prostate cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Enzalutamide in metastatic prostate cancer before chemotherapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dihydrotestosterone synthesis bypasses testosterone to drive castration-resistant prostate cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TALEN-engineered AR gene rearrangements reveal endocrine uncoupling of androgen receptor in prostate cancer.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Metastatic castration-resistant prostate cancer reveals intrapatient similarity and interpatient heterogeneity of therapeutic kinase targets
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prostate cancer originating in basal cells progresses to adenocarcinoma propagated by luminal-like cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
T cell infiltration of the prostate induced by androgen withdrawal in patients with prostate cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sequence of the intron/exon junctions of the coding region of the human androgen receptor gene and identification of a point mutation in a family with complete androgen insensitivity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Substrate specificity, gene structure, and tissue-specific distribution of multiple human 3 alpha-hydroxysteroid dehydrogenases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of the androgen receptor N-terminal domain by interleukin-6 via MAPK and STAT3 signal transduction pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Androgen receptor splice variants activate androgen receptor target genes and support aberrant prostate cancer cell growth independent of canonical androgen receptor nuclear localization signal
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Coregulator control of androgen receptor action by a novel nuclear receptor-binding motif
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ligand-independent activation of the androgen receptor by interleukin-6 and the role of steroid receptor coactivator-1 in prostate cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of multidrug resistance genes in normal and cancer stem cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Modeling the prostate stem cell niche: an evaluation of stem cell survival and expansion in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of androgens and the androgen receptor in epithelial-mesenchymal transition and invasion of prostate cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Androgen Receptor Gene Amplification and Protein Expression in Recurrent Prostate Cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Proposed morphologic classification of prostate cancer with neuroendocrine differentiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Is there an antiandrogen withdrawal syndrome with enzalutamide?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
5alphaDH-DOC (5alpha-dihydro-deoxycorticosterone) activates androgen receptor in castration-resistant prostate cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor growth need not be driven by rare cancer stem cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Development of a second-generation antiandrogen for treatment of advanced prostate cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Androgen induces a switch from cytoplasmic retention to nuclear import of the androgen receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Antiandrogen bicalutamide promotes tumor growth in a novel androgen-dependent prostate cancer xenograft model derived from a bicalutamide-treated patient
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prospective identification of tumorigenic prostate cancer stem cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased expression of genes converting adrenal androgens to testosterone in androgen-independent prostate cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inappropriate activation of the androgen receptor by nonsteroids: involvement of the Src kinase pathway and its therapeutic implications
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Androgen deprivation increases p300 expression in prostate cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intraprostatic androgens and androgen-regulated gene expression persist after testosterone suppression: therapeutic implications for castration-resistant prostate cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prostate cancer cells with stem cell characteristics reconstitute the original human tumor in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for calpain-mediated androgen receptor cleavage as a mechanism for androgen independence
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Androgen levels increase by intratumoral de novo steroidogenesis during progression of castration-resistant prostate cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ligand-independent androgen receptor variants derived from splicing of cryptic exons signify hormone-refractory prostate cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased expression of androgen receptor sensitizes prostate cancer cells to low levels of androgens.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence of limited contributions for intratumoral steroidogenesis in prostate cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of the glucocorticoid receptor is associated with poor prognosis in estrogen receptor-negative breast cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Androgen deprivation causes epithelial-mesenchymal transition in the prostate: implications for androgen-deprivation therapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Distinct transcriptional programs mediated by the ligand-dependent full-length androgen receptor and its splice variants in castration-resistant prostate cancer.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Androgen receptor splice variants mediate enzalutamide resistance in castration-resistant prostate cancer cell lines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
JAK-STAT blockade inhibits tumor initiation and clonogenic recovery of prostate cancer stem-like cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
High fidelity patient-derived xenografts for accelerating prostate cancer discovery and drug development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Androgen receptor is the key transcriptional mediator of the tumor suppressor SPOP in prostate cancer.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intracrine Androgens and AKR1C3 Activation Confer Resistance to Enzalutamide in Prostate Cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Steroid 5alpha-reductase isozymes I and II in recurrent prostate cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Circulating Tumor Cell Analysis in Patients with Progressive Castration-Resistant Prostate Cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Resistance to CYP17A1 inhibition with abiraterone in castration-resistant prostate cancer: induction of steroidogenesis and androgen receptor splice variants
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular pathways: resistance to kinase inhibitors and implications for therapeutic strategies
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rapid induction of androgen receptor splice variants by androgen deprivation in prostate cancer.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Abiraterone treatment in castration-resistant prostate cancer selects for progesterone responsive mutant androgen receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ERG/AKR1C3/AR Constitutes a Feed-Forward Loop for AR Signaling in Prostate Cancer Cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Androgen Receptor Gene Aberrations in Circulating Cell-Free DNA: Biomarkers of Therapeutic Resistance in Castration-Resistant Prostate Cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Notch signaling modulates hypoxia-induced neuroendocrine differentiation of human prostate cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular characterization of neuroendocrine prostate cancer and identification of new drug targets
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Opposing effects of androgen deprivation and targeted therapy on prostate cancer prevention
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An F876L mutation in androgen receptor confers genetic and phenotypic resistance to MDV3100 (enzalutamide).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A clinically relevant androgen receptor mutation confers resistance to second-generation antiandrogens enzalutamide and ARN-509.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of high cell density in the promotion of neuroendocrine transdifferentiation of prostate cancer cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A hormone-dependent feedback-loop controls androgen receptor levels by limiting MID1, a novel translation enhancer and promoter of oncogenic signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Polycomb-mediated silencing in neuroendocrine prostate cancer.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Flutamide withdrawal syndrome: its impact on clinical trials in hormone-refractory prostate cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutation of histidine 874 in the androgen receptor ligand-binding domain leads to promiscuous ligand activation and altered p160 coactivator interactions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Androgen modulation of coregulator expression in prostate cancer cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dehydroepiandrosterone activates mutant androgen receptors expressed in the androgen-dependent human prostate cancer xenograft CWR22 and LNCaP cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Autologous down-regulation of androgen receptor messenger ribonucleic acid
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Domains of the Human Androgen Receptor Involved in Steroid Binding, Transcriptional Activation, and Subcellular Localization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sox2 is an androgen receptor-repressed gene that promotes castration-resistant prostate cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Constitutively active androgen receptor variants upregulate expression of mesenchymal markers in prostate cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A three-marker FISH panel detects more genetic aberrations of AR, PTEN and TMPRSS2/ERG in castration-resistant or metastatic prostate cancers than in primary prostate tumors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of prostate cancer bone metastases according to expression levels of steroidogenic enzymes and androgen receptor splice variants
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Use of prednisone with abiraterone acetate in metastatic castration-resistant prostate cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin-6 stimulation of growth of prostate cancer in vitro and in vivo through activation of the androgen receptor.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Androgen deprivation induces human prostate epithelial neuroendocrine differentiation of androgen-sensitive LNCaP cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of protein kinase A pathway and cAMP responsive element-binding protein in androgen receptor-mediated transcription at the prostate-specific antigen locus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanistic rationale for MCL1 inhibition during androgen deprivation therapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Studies on Prostatic Cancer: I. The Effect of Castration, Of Estrogen and of Androgen Injection on Serum Phosphatases in Metastatic Carcinoma of the Prostate
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Activity of SN33638, an Inhibitor of AKR1C3, on Testosterone and 17β-Estradiol Production and Function in Castration-Resistant Prostate Cancer and ER-Positive Breast Cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Suppression of metallothionein 3 gene expression by androgen in LNCaP prostate cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Androgen-deprivation therapy-induced aggressive prostate cancer with neuroendocrine differentiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential targeting of androgen and glucocorticoid receptors induces ER stress and apoptosis in prostate cancer cells: a novel therapeutic modality
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Beyond T and DHT - novel steroid derivatives capable of wild type androgen receptor activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCANCER.2015.08.005
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/J.SEMCANCER.2015.08.005
1 reference
stated in
Europe PubMed Central
PubMed ID
26299608
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26299608%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 February 2020
PubMed ID
26299608
1 reference
stated in
Europe PubMed Central
PubMed ID
26299608
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26299608%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 February 2020
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