(Q38986420)

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A hormone-dependent feedback-loop controls androgen receptor levels by limiting MID1, a novel translation enhancer and promoter of oncogenic signaling

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Europe PubMed Central

PMC publication ID

8 September 2017

A hormone-dependent feedback-loop controls androgen receptor levels by limiting MID1, a novel translation enhancer and promoter of oncogenic signaling (English)

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

author name string

Andrea Köhler

1

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Ummühan Demir

2

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Eva Kickstein

3

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Sybille Krauss

4

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Johanna Aigner

5

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Beatriz Aranda-Orgillés

6

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Antonios I Karagiannidis

7

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Clemens Achmüller

8

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Huajie Bu

9

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Andrea Wunderlich

10

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Michal-Ruth Schweiger

11

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Georg Schaefer

12

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Susann Schweiger

13

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Helmut Klocker

14

1 reference

Europe PubMed Central

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8 September 2017

Rainer Schneider

15

1 reference

Europe PubMed Central

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8 September 2017

publication date

9 June 2014

1 reference

Europe PubMed Central

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8 September 2017

Molecular Cancer

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

13

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

146

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Insulin sensitizers in polycystic ovary syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

9 September 2017

Posttranslational modification of the androgen receptor in prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

9 September 2017

The role of androgen receptor activity mediated by the CAG repeat polymorphism in the pathogenesis of PCOS

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

9 September 2017

A pleiotropic role for the orphan nuclear receptor small heterodimer partner in lipid homeostasis and metabolic pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

9 September 2017

Novel therapeutics for the management of castration-resistant prostate cancer (CRPC).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

9 September 2017

Androgen receptor gene expression in prostate cancer is directly suppressed by the androgen receptor through recruitment of lysine-specific demethylase 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

9 September 2017

Intratumoral de novo steroid synthesis activates androgen receptor in castration-resistant prostate cancer and is upregulated by treatment with CYP17A1 inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

9 September 2017

Targeting PDK1 in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

9 September 2017

Control of mTORC1 signaling by the Opitz syndrome protein MID1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

9 September 2017

Modulation of protein phosphatase 2A activity alters androgen-independent growth of prostate cancer cells: therapeutic implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

9 September 2017

Biguanide metformin acts on tau phosphorylation via mTOR/protein phosphatase 2A (PP2A) signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

9 September 2017

46,XY disorders of sex development--the undermasculinised male with disorders of androgen action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

9 September 2017

Inhibition of cyclin D1 expression by androgen receptor in breast cancer cells--identification of a novel androgen response element

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

9 September 2017

NF-kappaB and cancer: how intimate is this relationship

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

9 September 2017

3-Phosphoinositide-dependent kinase 1 potentiates upstream lesions on the phosphatidylinositol 3-kinase pathway in breast carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

9 September 2017

Castration-resistant prostate cancer: locking up the molecular escape routes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

9 September 2017

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

9 September 2017

Active transport of the ubiquitin ligase MID1 along the microtubules is regulated by protein phosphatase 2A

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

9 September 2017

Model-based analysis of ChIP-Seq (MACS)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

9 September 2017

Protein phosphatase 2A and rapamycin regulate the nuclear localization and activity of the transcription factor GLI3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

9 September 2017

Smith-Lemli-Opitz syndrome: pathogenesis, diagnosis and management

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

9 September 2017

A hierarchical network of transcription factors governs androgen receptor-dependent prostate cancer growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

9 September 2017

The androgen receptor mRNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

9 September 2017

Androgen receptor in prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

9 September 2017

NF??B: A Pivotal Transcription Factor in Prostate Cancer Metastasis to Bone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

9 September 2017

RNA-binding proteins that target the androgen receptor mRNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

9 September 2017

The MID1/PP2A complex: a key to the pathogenesis of Opitz BBB/G syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

9 September 2017

Protein phosphatase 2A and phosphoprotein SET regulate androgen production by P450c17

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

9 September 2017

Novel binding of HuR and poly(C)-binding protein to a conserved UC-rich motif within the 3'-untranslated region of the androgen receptor messenger RNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

9 September 2017

MID1, mutated in Opitz syndrome, encodes an ubiquitin ligase that targets phosphatase 2A for degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

9 September 2017

Metformin inhibits the senescence-associated secretory phenotype by interfering with IKK/NF-κB activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

9 September 2017

Protein phosphatase 2A (PP2A)-specific ubiquitin ligase MID1 is a sequence-dependent regulator of translation efficiency controlling 3-phosphoinositide-dependent protein kinase-1 (PDPK-1).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

9 September 2017

Overexpression of androgen receptor enhances the binding of the receptor to the chromatin in prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

9 September 2017

Reciprocal feedback regulation of PI3K and androgen receptor signaling in PTEN-deficient prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

9 September 2017

Mutant CAG repeats of Huntingtin transcript fold into hairpins, form nuclear foci and are targets for RNA interference

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

14 September 2017

An in vitro model for preclinical testing of endocrine therapy combinations for prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

14 September 2017

The poly(c)-binding protein-1 regulates expression of the androgen receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

14 September 2017

A five-gene signature as a potential predictor of metastasis and survival in colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

14 September 2017

Prostate cancer progression into androgen independency is associated with alterations in cell adhesion and invasivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

14 September 2017

Multiple androgen response elements and a Myc consensus site in the androgen receptor (AR) coding region are involved in androgen-mediated up-regulation of AR messenger RNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

25 September 2017

Androgenic up-regulation of androgen receptor cDNA expression in androgen-independent prostate cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

25 September 2017

Somatic mutations throughout the entire mitochondrial genome are associated with elevated PSA levels in prostate cancer patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

25 September 2017

Metformin anti-tumor effect via disruption of the MID1 translational regulator complex and AR downregulation in prostate cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

17 June 2018

Translation of HTT mRNA with expanded CAG repeats is regulated by the MID1-PP2A protein complex.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

21 August 2018

The E3 ubiquitin ligase midline 1 promotes allergen and rhinovirus-induced asthma by inhibiting protein phosphatase 2A activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

21 August 2018

Anterior gradient 2 and 3--two prototype androgen-responsive genes transcriptionally upregulated by androgens and by oestrogens in prostate cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

21 August 2018

Lower serum total testosterone is associated with lymph node metastases in a radical prostatectomy cohort study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

21 August 2018

A feedback loop between the androgen receptor and a NEDD4-binding protein, PMEPA1, in prostate cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

21 August 2018

The two most common alleles of the coding GGN repeat in the androgen receptor gene cause differences in protein function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

21 August 2018

High-grade prostate cancer is associated with low serum testosterone levels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074869

21 August 2018

Association between the dihydrotestosterone level in the prostate and prostate cancer aggressiveness using the Gleason score

1 reference

https://pubmed.ncbi.nlm.nih.gov/24913494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of immunoglobulin (CD79a) binding protein1 (IGBP-1) in small lung adenocarcinomas and its clinicopathological significance

1 reference

https://pubmed.ncbi.nlm.nih.gov/24913494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced androgen receptor gene expression with first exon CAG repeat expansion

1 reference

https://pubmed.ncbi.nlm.nih.gov/24913494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autoregulation of androgen receptor in rat ventral prostate: involvement of c-fos as a negative regulator

1 reference

https://pubmed.ncbi.nlm.nih.gov/24913494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1476-4598-13-146

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

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PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

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