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Small-molecule based musculoskeletal regenerative engineering
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PubMed
title
Small-molecule based musculoskeletal regenerative engineering
(English)
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stated in
PubMed
author
Cato T. Laurencin
series ordinal
5
object named as
Cato T. Laurencin
1 reference
stated in
Crossref
author name string
Kevin W.-H. Lo
series ordinal
1
1 reference
stated in
Crossref
Tao Jiang
series ordinal
2
1 reference
stated in
Crossref
Keith A. Gagnon
series ordinal
3
1 reference
stated in
Crossref
Clarke Nelson
series ordinal
4
1 reference
stated in
Crossref
language of work or name
English
1 reference
stated in
PubMed
publication date
February 2014
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stated in
PubMed
published in
Trends in Biotechnology
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stated in
PubMed
volume
32
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stated in
PubMed
issue
2
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stated in
PubMed
page(s)
74-81
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stated in
PubMed
cites work
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Alendronate reduced peri-tunnel bone loss and enhanced tendon graft to bone tunnel healing in anterior cruciate ligament reconstruction
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7 April 2017
Autograft versus nonirradiated allograft tissue for anterior cruciate ligament reconstruction: a systematic review
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Increased sphingosine-1-phosphate improves muscle regeneration in acutely injured mdx mice
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Strontium ranelate reduces cartilage degeneration and subchondral bone remodeling in rat osteoarthritis model
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Bone morphogenetic protein-inducer tilorone identified by high-throughput screening is antifibrotic in vivo
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28 September 2017
Crosslinking strategies facilitate tunable structural properties of fibrin microthreads
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28 September 2017
The role of small molecules in musculoskeletal regeneration
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28 September 2017
Evaluating the feasibility of utilizing the small molecule phenamil as a novel biofactor for bone regenerative engineering
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28 September 2017
A novel library screen identifies immunosuppressors that promote osteoblast differentiation
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28 September 2017
Nanostructured polymeric scaffolds for orthopaedic regenerative engineering
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28 September 2017
Small molecules that recapitulate the early steps of urodele amphibian limb regeneration and confer multipotency.
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28 September 2017
Neural cell type-specific responses to glycomimetic functionalized collagen
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28 September 2017
Current clinical therapies for cartilage repair, their limitation and the role of stem cells.
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28 September 2017
Subchondral bone as a key target for osteoarthritis treatment.
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28 September 2017
Effects of dibutyryl cyclic-AMP on survival and neuronal differentiation of neural stem/progenitor cells transplanted into spinal cord injured rats
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28 September 2017
Tiludronate treatment improves structural changes and symptoms of osteoarthritis in the canine anterior cruciate ligament model
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28 September 2017
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28 September 2017
A synthetic compound that potentiates bone morphogenetic protein-2-induced transdifferentiation of myoblasts into the osteoblastic phenotype
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
Small molecule screening in zebrafish: an in vivo approach to identifying new chemical tools and drug leads
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28 September 2017
Articular cartilage and subchondral bone in the pathogenesis of osteoarthritis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992320
retrieved
28 September 2017
Sphingosine 1-phosphate signaling is involved in skeletal muscle regeneration
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992320
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28 September 2017
Retinoic acid enhances skeletal muscle progenitor formation and bypasses inhibition by bone morphogenetic protein 4 but not dominant negative beta-catenin.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992320
retrieved
28 September 2017
The small molecule phenamil induces osteoblast differentiation and mineralization
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992320
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28 September 2017
Bone morphogenetic proteins in tissue engineering: the road from laboratory to clinic, part II (BMP delivery).
1 reference
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992320
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28 September 2017
Recognizing and exploiting differences between RNAi and small-molecule inhibitors
1 reference
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28 September 2017
Current and future clinical applications of bone morphogenetic proteins in orthopaedic trauma surgery.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992320
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28 September 2017
Peripheral regeneration
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992320
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28 September 2017
Mechanism of osteogenic induction by FK506 via BMP/Smad pathways
1 reference
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992320
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28 September 2017
Peripheral nerve regeneration.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992320
retrieved
28 September 2017
Anterior cruciate ligament reconstruction: which graft is best?
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992320
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28 September 2017
Looking back to the embryo: defining transcriptional networks in adult myogenesis.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992320
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28 September 2017
Strontium ranelate increases cartilage matrix formation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992320
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28 September 2017
One-day treatment of small molecule 8-bromo-cyclic AMP analogue induces cell-based VEGF production for in vitro angiogenesis and osteoblastic differentiation
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992320
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31 May 2018
Metalloproteases and tendinopathy
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992320
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31 May 2018
A novel low-molecular-weight compound enhances ectopic bone formation and fracture repair
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992320
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31 May 2018
Polysialic acid glycomimetics promote myelination and functional recovery after peripheral nerve injury in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992320
retrieved
31 May 2018
Nonyloxytryptamine mimics polysialic acid and modulates neuronal and glial functions in cell culture
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992320
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28 November 2018
Short-term administration of small molecule phenamil induced a protracted osteogenic effect on osteoblast-like MC3T3-E1 cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992320
retrieved
28 November 2018
Cancer after spinal fusion: the role of bone morphogenetic protein
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992320
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28 November 2018
Bone morphogenetic proteins for bone regeneration and their alternatives
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992320
retrieved
28 November 2018
Regenerative engineering.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992320
retrieved
28 November 2018
Strontium ranelate reduces the progression of experimental dog osteoarthritis by inhibiting the expression of key proteases in cartilage and of IL-1β in the synovium.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992320
retrieved
28 November 2018
Inhibition of osteoclasts prevents cartilage loss and pain in a rat model of degenerative joint disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992320
retrieved
28 November 2018
Bone morphogenetic protein binding peptide mechanism and enhancement of osteogenic protein-1 induced bone healing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992320
retrieved
28 November 2018
Inhibition of bone resorption blunts osteoarthritis in mice with high bone remodelling.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992320
retrieved
28 November 2018
db-Cyclic adenosine monophosphate promotes axon regeneration and motor function recovery in cerebral ischemia-reperfusion rats
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992320
retrieved
28 November 2018
Differential expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in anterior cruciate ligament and medial collateral ligament fibroblasts after a mechanical injury: involvement of the p65 subunit of NF-kappaB.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992320
retrieved
28 November 2018
Protective effects of licofelone, a 5-lipoxygenase and cyclo-oxygenase inhibitor, versus naproxen on cartilage loss in knee osteoarthritis: a first multicentre clinical trial using quantitative MRI.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992320
retrieved
28 November 2018
The role of macrophages in early healing of a tendon graft in a bone tunnel
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992320
retrieved
28 November 2018
A novel regulatory mechanism of the bone morphogenetic protein (BMP) signaling pathway involving the carboxyl-terminal tail domain of BMP type II receptor
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992320
retrieved
28 November 2018
The role of subchondral bone remodeling in osteoarthritis: reduction of cartilage degeneration and prevention of osteophyte formation by alendronate in the rat anterior cruciate ligament transection model
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992320
retrieved
28 November 2018
The inhibition of subchondral bone resorption in the early phase of experimental dog osteoarthritis by licofelone is associated with a reduction in the synthesis of MMP-13 and cathepsin K.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992320
retrieved
28 November 2018
Local administration of alendronate reduced peri-tunnel bone loss and promoted graft-bone tunnel healing with minimal systemic effect on bone in contralateral knee
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24405851
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Alendronate prevents bone loss and improves tendon-to-bone repair strength in a canine model
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24405851
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Enhancement of tendon-bone healing of anterior cruciate ligament grafts by blockage of matrix metalloproteinases
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24405851
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Protein stability in controlled-release systems
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24405851
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Osteoarthritis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24405851
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identification of novel 2-((1-(benzyl(2-hydroxy-2-phenylethyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamoyl)benzoic acid analogues as BMP-2 stimulators
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24405851
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Strontium ranelate effect in postmenopausal women with different clinical levels of osteoarthritis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24405851
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Strontium ranelate reduces the urinary level of cartilage degradation biomarker CTX-II in postmenopausal women
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24405851
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
TGF-β1 promoted MMP-2 mediated wound healing of anterior cruciate ligament fibroblasts through NF-κB
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24405851
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.TIBTECH.2013.12.002
0 references
PMC publication ID
3992320
1 reference
stated in
PubMed
PubMed publication ID
24405851
1 reference
stated in
PubMed
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