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Pyridine nucleotide regulation of cardiac intermediary metabolism
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title
Pyridine nucleotide regulation of cardiac intermediary metabolism
(English)
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PubMed
author name string
J. R. Ussher
series ordinal
1
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J. S. Jaswal
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2
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G. D. Lopaschuk
series ordinal
3
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language of work or name
English
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stated in
PubMed
publication date
17 August 2012
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PubMed
published in
Circulation Research
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stated in
PubMed
volume
111
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PubMed
issue
5
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stated in
PubMed
page(s)
628-41
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PubMed
cites work
The role of Na+/K+ ATPase activity during low flow ischemia in preventing myocardial injury: a 31P, 23Na and 87Rb NMR spectroscopic study
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Is lactate-induced myocardial ischaemic injury mediated by decreased pH or increased intracellular lactate?
1 reference
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reference URL
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inferred from DOI database lookup
Paradoxical effect of ischemic preconditioning on ischemic contracture? NMR studies of energy metabolism and intracellular pH in the rat heart
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Crossref
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Developmental regulation of the alpha-glycerophosphate shuttle in porcine myocardium.
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reference URL
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Control of mitochondrial respiration in the heart in vivo
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stated in
Crossref
reference URL
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retrieved
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inferred from DOI database lookup
Hormones and triacylglycerol metabolism under normoxic and ischemic conditions
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7 January 2021
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inferred from DOI database lookup
Pyruvate dehydrogenase inhibition by the inflammatory cytokine TNFα contributes to the pathogenesis of pulmonary arterial hypertension.
1 reference
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Targeting malonyl CoA inhibition of mitochondrial fatty acid uptake as an approach to treat cardiac ischemia/reperfusion
1 reference
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Mitochondrial complex I and NAD(P)H oxidase are major sources of exacerbated oxidative stress in pressure-overloaded ischemic-reperfused hearts
1 reference
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7 January 2021
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Glucose-6-phosphate dehydrogenase deficiency protects against coronary heart disease
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7 January 2021
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The energy-yielding oxidation of NADH by fumarate in submitochondrial particles of rat tissues.
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7 January 2021
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Fatty acid synthesis in heart
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Crossref
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inferred from DOI database lookup
Two protons are pumped from the mitochondrial matrix per electron transferred between NADH and ubiquinone
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7 January 2021
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Rapid stimulation of the hexose monophosphate shunt in the isolated perfused rat heart: Possible involvement of oxidized glutathione
1 reference
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Crossref
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7 January 2021
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inferred from DOI database lookup
Effects of ischemia and reperfusion on pyruvate dehydrogenase activity in isolated rat hearts
1 reference
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inferred from DOI database lookup
GLUCOSE METABOLISM BY THE HEXOSE MONOPHOSPHATE PATHWAY IN THE PERFUSED RAT HEART
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7 January 2021
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1 reference
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7 January 2021
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Phosphorylation–Dephosphorylation Cycles and the Regulation of Fuel Selection in Mammals
1 reference
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Crossref
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7 January 2021
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inferred from DOI database lookup
Targeting fatty acid and carbohydrate oxidation--a novel therapeutic intervention in the ischemic and failing heart.
1 reference
stated in
Crossref
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7 January 2021
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inferred from DOI database lookup
Upregulation of glucose-6-phosphate dehydrogenase and NAD(P)H oxidase activity increases oxidative stress in failing human heart
1 reference
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Crossref
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7 January 2021
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Negative regulators of cardiac hypertrophy.
1 reference
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7 January 2021
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1 reference
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Crossref
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Reversible pulmonary trunk banding. VI: Glucose-6-phosphate dehydrogenase activity in rapid ventricular hypertrophy in young goats
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1 reference
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High rates of residual fatty acid oxidation during mild ischemia decrease cardiac work and efficiency
1 reference
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Crossref
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Transient and long-lasting openings of the mitochondrial permeability transition pore can be monitored directly in intact cells by changes in mitochondrial calcein fluorescence
1 reference
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1 reference
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1 reference
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1 reference
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Crossref
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1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
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7 January 2021
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inferred from DOI database lookup
The Pyridine Nucleotide Cycle
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https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
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inferred from DOI database lookup
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1 reference
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Crossref
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7 January 2021
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Thioredoxin-1 gene delivery induces heme oxygenase-1 mediated myocardial preservation after chronic infarction in hypertensive rats
1 reference
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Crossref
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https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
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7 January 2021
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Control of the tricarboxylate cycle and its interactions with glycolysis during acetate utilization in rat heart
1 reference
stated in
Crossref
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https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
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7 January 2021
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inferred from DOI database lookup
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1 reference
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Crossref
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https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
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Crossref
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https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
retrieved
7 January 2021
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inferred from DOI database lookup
Franklin H. Epstein Lecture: Sirtuins, aging, and medicine
1 reference
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https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
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7 January 2021
based on heuristic
inferred from DOI database lookup
High rates of fatty acid oxidation during reperfusion of ischemic hearts are associated with a decrease in malonyl-CoA levels due to an increase in 5'-AMP-activated protein kinase inhibition of acetyl-CoA carboxylase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
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7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
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inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
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7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Poly(ADP-ribose) polymerase-1-dependent cardiac myocyte cell death during heart failure is mediated by NAD+ depletion and reduced Sir2alpha deacetylase activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The pentose phosphate pathway
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of ROS signal transduction by NADPH oxidase 4 localization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Anaerobic glycolysis and the development of ischaemic contracture in isolated rat heart
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The malonyl CoA axis as a potential target for treating ischaemic heart disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cardiac diacylglycerol accumulation in high fat-fed mice is associated with impaired insulin-stimulated glucose oxidation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stimulation of glucose oxidation protects against acute myocardial infarction and reperfusion injury
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of muscle carbohydrate metabolism during exercise 1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aldose reductase activation is a key component of myocardial response to ischemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sorbitol dehydrogenase: a novel target for adjunctive protection of ischemic myocardium
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Central role for aldose reductase pathway in myocardial ischemic injury
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lactate transporters (MCT proteins) in heart and skeletal muscles
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Contribution of polyol pathway to diabetes-induced oxidative stress
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
6-phosphogluconolactonase. Purification, properties and activities in various tissues
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Enzyme levels of the NADH shuttle systems: measurements in isolated muscle fibres from humans of differing physical activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reactive oxygen species and antioxidants in signal transduction and gene expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
AMPK alterations in cardiac physiology and pathology: enemy or ally?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Understanding the Warburg effect: the metabolic requirements of cell proliferation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Relation between work and phosphate metabolite in the in vivo paced mammalian heart
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ribose intervention in the cardiac pentose phosphate pathway is not species-specific
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Emerging roles of NAD+ and its metabolites in cell signaling.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fatty acid oxidation and malonyl-CoA decarboxylase in the vascular remodeling of pulmonary hypertension
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of Nogo and the mitochondria-endoplasmic reticulum unit in pulmonary hypertension
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The cell biology of acute myocardial ischemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Relationship between carbohydrate and lipid metabolism and the energy balance of heart muscle
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Control of mitochondrial respiration in the heart in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of oxidative phosphorylation in the mammalian cell
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of the atypical protein kinase Czeta in regulation of 5'-AMP-activated protein kinase in cardiac and skeletal muscle.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Superoxide production by NAD(P)H oxidase and mitochondria is increased in genetically obese and hyperglycemic rat heart and aorta before the development of cardiac dysfunction. The role of glucose-6-phosphate dehydrogenase-derived NADPH.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Myocardial fatty acid metabolism in health and disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Impaired myocardial fatty acid oxidation and reduced protein expression of retinoid X receptor-alpha in pacing-induced heart failure
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Thioredoxin-interacting protein controls cardiac hypertrophy through regulation of thioredoxin activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alpha-adrenergic receptor-stimulated hypertrophy in adult rat ventricular myocytes is mediated via thioredoxin-1-sensitive oxidative modification of thiols on Ras.
1 reference
stated in
Crossref
reference URL
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7 January 2021
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Glucose-6-phosphate dehydrogenase modulates cytosolic redox status and contractile phenotype in adult cardiomyocytes
1 reference
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Crossref
reference URL
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7 January 2021
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Beneficial effects of trimetazidine in ex vivo working ischemic hearts are due to a stimulation of glucose oxidation secondary to inhibition of long-chain 3-ketoacyl coenzyme a thiolase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
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7 January 2021
based on heuristic
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Malonyl coenzyme a decarboxylase inhibition protects the ischemic heart by inhibiting fatty acid oxidation and stimulating glucose oxidation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
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7 January 2021
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Dichloroacetate prevents and reverses pulmonary hypertension by inducing pulmonary artery smooth muscle cell apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
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7 January 2021
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Sustained currents through ASIC3 ion channels at the modest pH changes that occur during myocardial ischemia
1 reference
stated in
Crossref
reference URL
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7 January 2021
based on heuristic
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Analysis of metabolic remodeling in compensated left ventricular hypertrophy and heart failure
1 reference
stated in
Crossref
reference URL
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7 January 2021
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Targeted deletion of thioredoxin-interacting protein regulates cardiac dysfunction in response to pressure overload
1 reference
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Crossref
reference URL
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7 January 2021
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Substrate-enzyme competition attenuates upregulated anaplerotic flux through malic enzyme in hypertrophied rat heart and restores triacylglyceride content: attenuating upregulated anaplerosis in hypertrophy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
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7 January 2021
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Thioredoxin 1 negatively regulates angiotensin II-induced cardiac hypertrophy through upregulation of miR-98/let-7
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
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7 January 2021
based on heuristic
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Absence of malonyl coenzyme A decarboxylase in mice increases cardiac glucose oxidation and protects the heart from ischemic injury
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
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7 January 2021
based on heuristic
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Recruitment of compensatory pathways to sustain oxidative flux with reduced carnitine palmitoyltransferase I activity characterizes inefficiency in energy metabolism in hypertrophied hearts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
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7 January 2021
based on heuristic
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Emerging concepts and translational priorities in pulmonary arterial hypertension
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
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7 January 2021
based on heuristic
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Thioredoxin-1 gene therapy enhances angiogenic signaling and reduces ventricular remodeling in infarcted myocardium of diabetic rats
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
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7 January 2021
based on heuristic
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Deletion of cardiomyocyte mineralocorticoid receptor ameliorates adverse remodeling after myocardial infarction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
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7 January 2021
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Attenuation of angiotensin II-induced vascular dysfunction and hypertension by overexpression of Thioredoxin 2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
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7 January 2021
based on heuristic
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Calorie restriction prevents hypertension and cardiac hypertrophy in the spontaneously hypertensive rat.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
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7 January 2021
based on heuristic
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Inhibition of endogenous thioredoxin in the heart increases oxidative stress and cardiac hypertrophy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular pathogenesis of pulmonary arterial hypertension
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
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7 January 2021
based on heuristic
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Role of cellular compartmentation in the metabolic response to stress: mechanistic insights from computational models.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
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7 January 2021
based on heuristic
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The secret life of NAD+: an old metabolite controlling new metabolic signaling pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
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7 January 2021
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Aldose reductase inhibitors improve myocardial reperfusion injury in mice by a dual mechanism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
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7 January 2021
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Poly ADP-ribose polymerase-1 and health
1 reference
stated in
Crossref
reference URL
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7 January 2021
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Does the pentose cycle play a major role for NADPH supply in the heart?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
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7 January 2021
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Pharmacological stimulation of NADH oxidation ameliorates obesity and related phenotypes in mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Insulin-stimulated cardiac glucose oxidation is increased in high-fat diet-induced obese mice lacking malonyl CoA decarboxylase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aldose reductase inhibition protects diabetic and nondiabetic rat hearts from ischemic injury
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1161%2FCIRCRESAHA.111.246371
retrieved
7 January 2021
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Identifiers
DOI
10.1161/CIRCRESAHA.111.246371
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1734939
OpenCitations bibliographic resource ID
1734939
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1734939
PubMed ID
22904042
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1734939
ResearchGate publication ID
230698903
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