(Q34808534)

4 August 2017

1 reference

title

Cardiac anaplerosis in health and disease: food for thought (English)

1 reference

4 August 2017

author name string

Christine Des Rosiers

1

1 reference

4 August 2017

François Labarthe

2

1 reference

4 August 2017

Steven G Lloyd

3

1 reference

4 August 2017

John C Chatham

4

1 reference

4 August 2017

publication date

11 March 2011

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4 August 2017

published in

Cardiovascular Research

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4 August 2017

volume

90

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4 August 2017

issue

2

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4 August 2017

page(s)

210-219

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NAD: a master regulator of transcription.

4 August 2017

cites work

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Competition of pyruvate with physiological substrates for oxidation by the heart: implications for studies with hyperpolarized [1-13C]pyruvate.

8 July 2018

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SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

8 July 2018

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Shedding light on the enigma of myocardial lipotoxicity: the involvement of known and putative regulators of fatty acid storage and mobilization.

8 July 2018

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8 July 2018

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13C NMR tracers in neurochemistry: implications for molecular imaging.

8 July 2018

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8 July 2018

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Dipropionylcysteine ethyl ester compensates for loss of citric acid cycle intermediates during post ischemia reperfusion in the pig heart

8 July 2018

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Micronutrient deficiencies an unmet need in heart failure

8 July 2018

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The adrenergic-fatty acid load in heart failure

8 July 2018

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Alterations in mitochondrial function as a harbinger of cardiomyopathy: lessons from the dystrophic heart

8 July 2018

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Treating heart failure with sildenafil

8 July 2018

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The role of protein O-linked beta-N-acetylglucosamine in mediating cardiac stress responses.

8 July 2018

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Understanding the Warburg effect: the metabolic requirements of cell proliferation

8 July 2018

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A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance

8 July 2018

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Substrate-enzyme competition attenuates upregulated anaplerotic flux through malic enzyme in hypertrophied rat heart and restores triacylglyceride content: attenuating upregulated anaplerosis in hypertrophy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078802

Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction

8 July 2018

1 reference

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Energy metabolism in heart failure and remodelling

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078802

Superior cardiac function via anaplerotic pyruvate in the immature swine heart after cardiopulmonary bypass and reperfusion

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078802

Cardiac mitochondria in heart failure: decrease in respirasomes and oxidative phosphorylation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078802

Carnitine palmitoyltransferase II deficiency: successful anaplerotic diet therapy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078802

Cyclic GMP signaling in cardiomyocytes modulates fatty acid trafficking and prevents triglyceride accumulation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078802

Sildenafil and cardiomyocyte-specific cGMP signaling prevent cardiomyopathic changes associated with dystrophin deficiency

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078802

Succination of proteins by fumarate: mechanism of inactivation of glyceraldehyde-3-phosphate dehydrogenase in diabetes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078802

Nonischemic heart failure in diabetes mellitus

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078802

Role of diet and fuel overabundance in the development and progression of heart failure

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078802

Tackling heart failure in the twenty-first century

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078802

Medium-chain fatty acids as metabolic therapy in cardiac disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078802

Metabolic (in)flexibility of the diabetic heart

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078802

Diabetic cardiomyopathy revisited

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078802

Mass isotopomer study of anaplerosis from propionate in the perfused rat heart

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078802

The failing heart--an engine out of fuel

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078802

Drug discovery for heart failure: a new era or the end of the pipeline?

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078802

Inhibition of hypoxia-inducible factor (HIF) hydroxylases by citric acid cycle intermediates: possible links between cell metabolism and stabilization of HIF.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078802

Anaplerotic molecules: current and future

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078802

Tricarboxylic acid cycle dysfunction as a cause of human diseases and tumor formation.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078802

Role of changes in cardiac metabolism in development of diabetic cardiomyopathy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078802

Pyruvate carboxylase deficiency: metabolic characteristics and new neurological aspects

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078802

Metabolic cardioprotection by pyruvate: recent progress.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078802

Heme oxygenase and the cardiovascular-renal system

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078802

Therapeutic effects of L-carnitine and propionyl-L-carnitine on cardiovascular diseases: a review

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078802

Heme, iron, and the mitochondrial decay of ageing

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078802

Citric acid cycle intermediates as ligands for orphan G-protein-coupled receptors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078802

Metabolic remodelling of the failing heart: the cardiac burn-out syndrome?

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078802

Assessing the reversibility of the anaplerotic reactions of the propionyl-CoA pathway in heart and liver

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078802

Treatment of cardiomyopathy and rhabdomyolysis in long-chain fat oxidation disorders using an anaplerotic odd-chain triglyceride

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078802

The key role of anaplerosis and cataplerosis for citric acid cycle function.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078802

Aconitase: sensitive target and measure of superoxide

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078802

Anaplerosis of the citric acid cycle: role in energy metabolism of heart and skeletal muscle

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078802

Recognition and management of fatty acid oxidation defects: a series of 107 patients.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078802

Haemodynamic effects of intracoronary pyruvate in patients with congestive heart failure: an open study

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078802

Malonyl-CoA, fuel sensing, and insulin resistance

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078802

Applications of mass isotopomer analysis to nutrition research

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078802

13C isotopomer model for estimation of anaplerotic substrate oxidation via acetyl-CoA.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078802

Are the beta-cell signaling molecules malonyl-CoA and cystolic long-chain acyl-CoA implicated in multiple tissue defects of obesity and NIDDM?

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078802

Effects of amino acids on substrate selection, anaplerosis, and left ventricular function in the ischemic reperfused rat heart.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078802

Pyruvate carboxylation as an anaplerotic mechanism in the isolated perfused rat heart

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078802

Elimination and replenishment of tricarboxylic acid-cycle intermediates in myocardium

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078802

The molecular basis for the two different clinical presentations of classical pyruvate carboxylase deficiency.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078802

Role of NADP+ (corrected)-linked malic enzymes as regulators of the pool size of tricarboxylic acid-cycle intermediates in the perfused rat heart

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078802

Carbon flux through citric acid cycle pathways in perfused heart by 13C NMR spectroscopy.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078802

Changes in citric acid cycle flux and anaplerosis antedate the functional decline in isolated rat hearts utilizing acetoacetate

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078802

Myocardial phenotyping using isotopomer analysis of metabolic fluxes

8 July 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR055

A critical perspective of the use of (13)C-isotopomer analysis by GCMS and NMR as applied to cardiac metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR055

Metabolic phenotyping of the diseased rat heart using 13C-substrates and ex vivo perfusion in the working mode

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR055

Differential modulation of citrate synthesis and release by fatty acids in perfused working rat hearts

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR055

Reverse flux through cardiac NADP(+)-isocitrate dehydrogenase under normoxia and ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR055

Differential effects of heptanoate and hexanoate on myocardial citric acid cycle intermediates following ischemia-reperfusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR055

Quantitative assessment of anaplerosis from propionate in pig heart in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR055

Probing the origin of acetyl-CoA and oxaloacetate entering the citric acid cycle from the 13C labeling of citrate released by perfused rat hearts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR055

Differential modulation of glucose, lactate, and pyruvate oxidation by insulin and dichloroacetate in the rat heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR055

Glutamine cycling in isolated working rat heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR055

Alterations in carbohydrate metabolism and its regulation in PPARalpha null mouse hearts

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR055

Altered global myocardial substrate preference at rest and during pacing in coronary artery disease with stable angina pectoris

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR055

Probing the link between citrate and malonyl-CoA in perfused rat hearts

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR055

Profiling substrate fluxes in the isolated working mouse heart using 13C-labeled substrates: focusing on the origin and fate of pyruvate and citrate carbons

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR055

Fatty acid oxidation and its impact on response of spontaneously hypertensive rat hearts to an adrenergic stress: benefits of a medium-chain fatty acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR055

Regulation of pyruvate dehydrogenase activity and citric acid cycle intermediates during high cardiac power generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR055

Post-ischemic treatment with dipyruvyl-acetyl-glycerol decreases myocardial infarct size in the pig

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR055

Non-invasive measurements of myocardial carbon metabolism using in vivo 13C NMR spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR055

Cardiomyopathies in propionic aciduria are reversible after liver transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR055

Mitochondrial fatty acid oxidation defects--remaining challenges.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR055

Modulation of mitochondrial function by hydrogen peroxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR055

Acute hibernation decreases myocardial pyruvate carboxylation and citrate release

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078802

Evidence of separate pathways for lactate uptake and release by the perfused rat heart

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078802

Prolonged QTc intervals and decreased left ventricular contractility in patients with propionic acidemia

26 October 2018

1 reference

12 December 2020

Recruitment of compensatory pathways to sustain oxidative flux with reduced carnitine palmitoyltransferase I activity characterizes inefficiency in energy metabolism in hypertrophied hearts

1 reference

12 December 2020

Metabolic and signaling alterations in dystrophin-deficient hearts precede overt cardiomyopathy

1 reference

12 December 2020

l-carnitine and its propionate: improvement of endothelial function in SHR through superoxide dismutase-dependent mechanisms

1 reference

12 December 2020

Regulation of malonyl-CoA concentration and turnover in the normal heart

1 reference

12 December 2020

Myocardial Exchanges of Glutamate, Alanine and Citrate in Controls and Patients with Coronary Artery Disease

1 reference

12 December 2020

Beneficial effect of a low-fat low-calorie diet on myocardial energy metabolism in patients with angina pectoris

1 reference

12 December 2020

Protection of the ischaemic myocardium by L-propionylcarnitine: effects on the recovery of cardiac output after ischaemia and reperfusion, carnitine transport, and fatty acid oxidation

1 reference

12 December 2020

Pathways of succinate formation and their contribution to improvement of cardiac function in the hypoxic rat heart

1 reference

12 December 2020

Metabolic effects of propionate, hexanoate and propionylcarnitine in normoxia, ischaemia and reperfusion. Does an anaplerotic substrate protect the ischaemic myocardium?

1 reference

12 December 2020

Modeling of liver citric acid cycle and gluconeogenesis based on 13C mass isotopomer distribution analysis of intermediates

1 reference

12 December 2020

Effects and metabolism of fumarate in the perfused rat heart. A 13C mass isotopomer study

1 reference

12 December 2020

A 13C mass isotopomer study of anaplerotic pyruvate carboxylation in perfused rat hearts

1 reference

12 December 2020

Effects of L-glutamine on post-ischaemic cardiac function: protection and rescue

1 reference

12 December 2020

Multiple OXPHOS deficiency in the liver, kidney, heart, and skeletal muscle of patients with methylmalonic aciduria and propionic aciduria

1 reference

12 December 2020

Citrate release by perfused rat hearts: a window on mitochondrial cataplerosis

1 reference

12 December 2020

Propionyl-L-carnitine effects on postischemic recovery of heart function and substrate oxidation in the diabetic rat

1 reference

12 December 2020

Partitioning of pyruvate between oxidation and anaplerosis in swine hearts

1 reference

12 December 2020

Dystrophin-deficient cardiomyocytes are abnormally vulnerable to mechanical stress-induced contractile failure and injury

1 reference

12 December 2020

Identifiers

DOI

10.1093/CVR/CVR055

1 reference

4 August 2017

1 reference

4 August 2017

1 reference