(Q34001546)

English

Inhibition of hypoxia-inducible factor (HIF) hydroxylases by citric acid cycle intermediates: possible links between cell metabolism and stabilization of HIF.

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

30 July 2017

Inhibition of hypoxia-inducible factor (HIF) hydroxylases by citric acid cycle intermediates: possible links between cell metabolism and stabilization of HIF. (English)

1 reference

Europe PubMed Central

30 July 2017

0 references

1 reference

based on heuristic

inferred from title

author name string

Peppi Koivunen

1

1 reference

Europe PubMed Central

30 July 2017

Maija Hirsilä

2

1 reference

Europe PubMed Central

30 July 2017

Anne M Remes

3

1 reference

Europe PubMed Central

30 July 2017

Ilmo E Hassinen

4

1 reference

Europe PubMed Central

30 July 2017

Kari I Kivirikko

5

1 reference

Europe PubMed Central

30 July 2017

Johanna Myllyharju

6

1 reference

Europe PubMed Central

30 July 2017

language of work or name

0 references

publication date

19 December 2006

1 reference

Europe PubMed Central

30 July 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

30 July 2017

282

1 reference

Europe PubMed Central

30 July 2017

4524-4532

1 reference

Europe PubMed Central

30 July 2017

7

1 reference

Europe PubMed Central

30 July 2017

Oxygen sensing by HIF hydroxylases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610415200

21 January 2018

Proline hydroxylation and gene expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610415200

21 January 2018

Targeting HIF-1 for cancer therapy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610415200

21 January 2018

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610415200

21 January 2018

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610415200

21 January 2018

HIF-1alpha binding to VHL is regulated by stimulus-sensitive proline hydroxylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610415200

21 January 2018

A conserved family of prolyl-4-hydroxylases that modify HIF

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610415200

21 January 2018

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610415200

21 January 2018

Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610415200

21 January 2018

Prolyl 4-hydroxylases, the key enzymes of collagen biosynthesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610415200

21 January 2018

Collagens, modifying enzymes and their mutations in humans, flies and worms

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610415200

21 January 2018

Characterization of the human prolyl 4-hydroxylases that modify the hypoxia-inducible factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610415200

21 January 2018

Determination and comparison of specific activity of the HIF-prolyl hydroxylases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610415200

21 January 2018

Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610415200

21 January 2018

Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610415200

21 January 2018

FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610415200

21 January 2018

Catalytic properties of the asparaginyl hydroxylase (FIH) in the oxygen sensing pathway are distinct from those of its prolyl 4-hydroxylases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610415200

21 January 2018

Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610415200

21 January 2018

HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: novel role of fumarate in regulation of HIF stability

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610415200

21 January 2018

Endogenous 2-oxoacids differentially regulate expression of oxygen sensors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610415200

21 January 2018

Reversible inactivation of HIF-1 prolyl hydroxylases allows cell metabolism to control basal HIF-1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610415200

21 January 2018

Effect of desferrioxamine and metals on the hydroxylases in the oxygen sensing pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610415200

21 January 2018

Characterization of the human prolyl 4-hydroxylase tetramer and its multifunctional protein disulfide-isomerase subunit synthesized in a baculovirus expression system

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610415200

21 January 2018

Mechanism of the Prolyl Hydroxylase Reaction. 1. Role of Co-substrates

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610415200

21 January 2018

Inhibition of prolyl hydroxylation and procollagen processing in chick-embryo calvaria by a derivative of pyridine-2,4-dicarboxylate. Characterization of the diethyl ester as a proinhibitor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610415200

21 January 2018

HCaRG is a novel regulator of renal epithelial cell growth and differentiation causing G2M arrest

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610415200

21 January 2018

HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610415200

21 January 2018

Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610415200

21 January 2018

Effects of hypobaric hypoxia on vascular endothelial growth factor and the acute phase response in subjects who are susceptible to high-altitude pulmonary oedema

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610415200

21 January 2018

Differentiating the functional role of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha (EPAS-1) by the use of RNA interference: erythropoietin is a HIF-2alpha target gene in Hep3B and Kelly cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610415200

21 January 2018

Disruption of oxygen homeostasis underlies congenital Chuvash polycythemia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610415200

21 January 2018

The von Hippel-Lindau tumor suppressor protein: new insights into oxygen sensing and cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610415200

21 January 2018

Accumulation of Krebs cycle intermediates and over-expression of HIF1alpha in tumours which result from germline FH and SDH mutations

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610415200

21 January 2018

On the association of succinate dehydrogenase mutations with hereditary paraganglioma

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610415200

21 January 2018

A role for mitochondrial enzymes in inherited neoplasia and beyond

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610415200

21 January 2018

Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610415200

21 January 2018

The R22X mutation of the SDHD gene in hereditary paraganglioma abolishes the enzymatic activity of complex II in the mitochondrial respiratory chain and activates the hypoxia pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610415200

21 January 2018

Characterization of the iron- and 2-oxoglutarate-binding sites of human prolyl 4-hydroxylase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610415200

21 January 2018

Identifiers

10.1074/JBC.M610415200

1 reference

Europe PubMed Central

30 July 2017

1 reference

Europe PubMed Central

30 July 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q34001546&oldid=1430992951"