(Q46575022)

23 December 2017

title

Accumulation of Krebs cycle intermediates and over-expression of HIF1alpha in tumours which result from germline FH and SDH mutations (English)

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23 December 2017

21

Tomlinson IP

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23 December 2017

author name string

Pollard PJ

1

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23 December 2017

Brière JJ

2

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23 December 2017

Alam NA

3

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23 December 2017

Barwell J

4

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23 December 2017

Barclay E

5

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23 December 2017

Wortham NC

6

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23 December 2017

Hunt T

7

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23 December 2017

Mitchell M

8

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23 December 2017

Olpin S

9

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23 December 2017

Moat SJ

10

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23 December 2017

Hargreaves IP

11

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23 December 2017

Heales SJ

12

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23 December 2017

Chung YL

13

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23 December 2017

Griffiths JR

14

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23 December 2017

Dalgleish A

15

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23 December 2017

McGrath JA

16

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23 December 2017

Gleeson MJ

17

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23 December 2017

Hodgson SV

18

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23 December 2017

Poulsom R

19

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23 December 2017

Rustin P

20

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23 December 2017

publication date

29 June 2005

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23 December 2017

published in

Human Molecular Genetics

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23 December 2017

volume

14

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23 December 2017

issue

15

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23 December 2017

page(s)

2231-2239

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23 December 2017

Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma

cites work

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI227

Mutations in SDHC cause autosomal dominant paraganglioma, type 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI227

Gene mutations in the succinate dehydrogenase subunit SDHB cause susceptibility to familial pheochromocytoma and to familial paraganglioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI227

Germline SDHD mutation in familial phaeochromocytoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI227

Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI227

Distinct clinical features of paraganglioma syndromes associated with SDHB and SDHD gene mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI227

Hereditary leiomyomatosis and renal cell cancer (HLRCC).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI227

Mutations in the fumarate hydratase gene cause hereditary leiomyomatosis and renal cell cancer in families in North America

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI227

Familial multiple cutaneous and uterine leiomyomas associated with papillary renal cell cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI227

Architecture of succinate dehydrogenase and reactive oxygen species generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI227

On the Origin of Cancer Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI227

A role for mitochondrial enzymes in inherited neoplasia and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI227

The TCA cycle and tumorigenesis: the examples of fumarate hydratase and succinate dehydrogenase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI227

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI227

Von Hippel-Lindau disease: clinical and molecular perspectives

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI227

Inactivation of the von Hippel-Lindau (VHL) tumour suppressor gene and allelic losses at chromosome arm 3p in primary renal cell carcinoma: evidence for a VHL-independent pathway in clear cell renal tumourigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI227

Early-onset renal cell carcinoma as a novel extraparaganglial component of SDHB-associated heritable paraganglioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI227

The R22X mutation of the SDHD gene in hereditary paraganglioma abolishes the enzymatic activity of complex II in the mitochondrial respiratory chain and activates the hypoxia pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI227

Functional consequences of a SDHB gene mutation in an apparently sporadic pheochromocytoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI227

Evidence of increased microvessel density and activation of the hypoxia pathway in tumours from the hereditary leiomyomatosis and renal cell cancer syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI227

Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI227

Array comparative genomic hybridization analysis of colorectal cancer cell lines and primary carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI227

DNA microarrays for comparative genomic hybridization based on DOP-PCR amplification of BAC and PAC clones

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI227

A simple spectrophotometric assay for fumarate hydratase in crude tissue extracts

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI227

Endogenous 2-oxoacids differentially regulate expression of oxygen sensors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI227

21 January 2018

Identifiers

DOI

10.1093/HMG/DDI227

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23 December 2017

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23 December 2017