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Development of autophagy inducers in clinical medicine
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instance of
scholarly article
1 reference
stated in
PubMed
review article
1 reference
stated in
Europe PubMed Central
title
Development of autophagy inducers in clinical medicine
(English)
1 reference
stated in
PubMed
main subject
autophagy
0 references
author
Patrice Codogno
series ordinal
3
0 references
Beth Levine
series ordinal
1
0 references
author name string
Milton Packer
series ordinal
2
1 reference
stated in
Crossref
language of work or name
English
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stated in
PubMed
publication date
January 2015
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stated in
PubMed
published in
Journal of Clinical Investigation
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stated in
PubMed
volume
125
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stated in
PubMed
issue
1
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stated in
PubMed
page(s)
14-24
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stated in
PubMed
cites work
EGFR-mediated Beclin 1 phosphorylation in autophagy suppression, tumor progression, and tumor chemoresistance
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Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis
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7 April 2017
Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth
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7 April 2017
Autophagy in immunity and inflammation
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Autophagy mediates pharmacological lifespan extension by spermidine and resveratrol
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Self and nonself: how autophagy targets mitochondria and bacteria
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Autophagy-mediated tumor promotion
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Autophagy modulation as a potential therapeutic target for diverse diseases
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EGFR inhibitor erlotinib delays disease progression but does not extend survival in the SOD1 mouse model of ALS
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7 April 2017
Autophagy in the Pathogenesis of Disease
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7 April 2017
Vitamin D inhibits human immunodeficiency virus type 1 and Mycobacterium tuberculosis infection in macrophages through the induction of autophagy
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Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations
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A block of autophagy in lysosomal storage disorders
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7 April 2017
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease
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7 April 2017
Identification of a candidate therapeutic autophagy-inducing peptide
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7 April 2017
Autophagy in infection, inflammation, and immunity
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7 April 2017
Autophagy: renovation of cells and tissues
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7 April 2017
The role of Atg proteins in autophagosome formation
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7 April 2017
Development by self-digestion: molecular mechanisms and biological functions of autophagy
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7 April 2017
Autophagy in human health and disease
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PubMed Central
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Autophagy-dependent anticancer immune responses induced by chemotherapeutic agents in mice
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7 April 2017
Autophagy and aging
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PubMed Central
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7 April 2017
TFEB links autophagy to lysosomal biogenesis
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7 April 2017
Autophagy in mammalian development and differentiation
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7 April 2017
A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells
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7 April 2017
mTOR: a pharmacologic target for autophagy regulation
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28 September 2017
Pharmacologic agents targeting autophagy
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PubMed Central
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28 September 2017
Caffeine prevents human prion protein-mediated neurotoxicity through the induction of autophagy
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PubMed Central
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28 September 2017
Genetic and chemical correction of cholesterol accumulation and impaired autophagy in hepatic and neural cells derived from Niemann-Pick Type C patient-specific iPS cells.
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28 September 2017
Autophagy and human disease: emerging themes
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PubMed Central
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28 September 2017
Cytotoxic autophagy in cancer therapy
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PubMed Central
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28 September 2017
Autophagy is critical for pancreatic tumor growth and progression in tumors with p53 alterations
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28 September 2017
Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense
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PubMed Central
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28 September 2017
Glucose starvation inhibits autophagy via vacuolar hydrolysis and induces plasma membrane internalization by down-regulating recycling.
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28 September 2017
Essential role for autophagy in the maintenance of immunological memory against influenza infection
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28 September 2017
Epidermal growth factor receptor inhibition slows progression of diabetic nephropathy in association with a decrease in endoplasmic reticulum stress and an increase in autophagy
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28 September 2017
Autophagy--a key player in cellular and body metabolism
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28 September 2017
The impact of autophagy on cell death modalities.
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28 September 2017
A Crohn's disease variant in Atg16l1 enhances its degradation by caspase 3.
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28 September 2017
Nilotinib-induced autophagic changes increase endogenous parkin level and ubiquitination, leading to amyloid clearance
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28 September 2017
Autophagy and human diseases
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28 September 2017
p53 status determines the role of autophagy in pancreatic tumour development
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28 September 2017
Impaired autophagy in the lipid-storage disorder Niemann-Pick type C1 disease
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28 September 2017
Autosis is a Na+,K+-ATPase-regulated form of cell death triggered by autophagy-inducing peptides, starvation, and hypoxia-ischemia
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28 September 2017
Exploiting the bad eating habits of Ras-driven cancers
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28 September 2017
Regulation of autophagy by mTOR-dependent and mTOR-independent pathways: autophagy dysfunction in neurodegenerative diseases and therapeutic application of autophagy enhancers.
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28 September 2017
Chemical screening platforms for autophagy drug discovery to identify therapeutic candidates for Huntington's disease and other neurodegenerative disorders.
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28 September 2017
Autophagy inhibition radiosensitizes in vitro, yet reduces radioresponses in vivo due to deficient immunogenic signalling
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28 September 2017
Therapeutic targeting of autophagy in disease: biology and pharmacology
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28 September 2017
Caffeine stimulates hepatic lipid metabolism by the autophagy-lysosomal pathway in mice.
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28 September 2017
Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis
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28 September 2017
Emerging regulation and functions of autophagy
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28 September 2017
Autophagy in tumour cell death
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28 September 2017
Autophagosome formation--the role of ULK1 and Beclin1-PI3KC3 complexes in setting the stage.
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28 September 2017
miR-30a downregulation aggravates pressure overload-induced cardiomyocyte hypertrophy
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28 September 2017
Diminished autophagy limits cardiac injury in mouse models of type 1 diabetes
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28 September 2017
Signals from the lysosome: a control centre for cellular clearance and energy metabolism
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28 September 2017
Transcription factor EB (TFEB) is a new therapeutic target for Pompe disease
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28 September 2017
The regulatory role of NF-κB in autophagy-like cell death after focal cerebral ischemia in mice
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28 September 2017
Ubiquitin-independent function of optineurin in autophagic clearance of protein aggregates
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28 September 2017
Epidermal growth factor receptor is a preferred target for treating amyloid-β-induced memory loss
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28 September 2017
Ubiquitination and selective autophagy
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28 September 2017
Inhibition of autophagy ameliorates acute lung injury caused by avian influenza A H5N1 infection.
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28 September 2017
Autophagy required for hepatitis B virus replication in transgenic mice
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28 September 2017
Concurrent detection of autolysosome formation and lysosomal degradation by flow cytometry in a high-content screen for inducers of autophagy
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28 September 2017
Sorafenib enhances pemetrexed cytotoxicity through an autophagy-dependent mechanism in cancer cells
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28 September 2017
Hormonally active vitamin D3 (1alpha,25-dihydroxycholecalciferol) triggers autophagy in human macrophages that inhibits HIV-1 infection
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28 September 2017
Oncogenic Ras-induced expression of Noxa and Beclin-1 promotes autophagic cell death and limits clonogenic survival
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382267
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28 September 2017
Autophagosomes and human diseases
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382267
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28 September 2017
Autophagy protein microtubule-associated protein 1 light chain-3B (LC3B) activates extrinsic apoptosis during cigarette smoke-induced emphysema
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28 September 2017
An autophagy-enhancing drug promotes degradation of mutant alpha1-antitrypsin Z and reduces hepatic fibrosis.
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28 September 2017
Targeting the prodeath and prosurvival functions of autophagy as novel therapeutic strategies in cancer
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28 September 2017
Rilmenidine attenuates toxicity of polyglutamine expansions in a mouse model of Huntington's disease
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28 September 2017
In vivo requirement for Atg5 in antigen presentation by dendritic cells
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382267
retrieved
28 September 2017
Autophagy regulates pancreatic beta cell death in response to Pdx1 deficiency and nutrient deprivation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382267
retrieved
28 September 2017
The role of exercise and PGC1alpha in inflammation and chronic disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382267
retrieved
28 September 2017
Bcl-2 family members: dual regulators of apoptosis and autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382267
retrieved
28 September 2017
Inhibition of autophagy prevents hippocampal pyramidal neuron death after hypoxic-ischemic injury
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382267
retrieved
28 September 2017
Small molecule regulators of autophagy identified by an image-based high-throughput screen
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382267
retrieved
28 September 2017
Alternate-day fasting and chronic disease prevention: a review of human and animal trials
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382267
retrieved
28 September 2017
Cardiac autophagy is a maladaptive response to hemodynamic stress
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382267
retrieved
28 September 2017
Small molecules enhance autophagy and reduce toxicity in Huntington's disease models.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382267
retrieved
28 September 2017
Dynein mutations impair autophagic clearance of aggregate-prone proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382267
retrieved
28 September 2017
Autophagy in metazoans: cell survival in the land of plenty
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382267
retrieved
28 September 2017
Vitamin D analog EB1089 triggers dramatic lysosomal changes and Beclin 1-mediated autophagic cell death.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382267
retrieved
28 September 2017
Restriction of food intake prevents postinfarction heart failure by enhancing autophagy in the surviving cardiomyocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382267
retrieved
31 May 2018
Glucose-starved cells do not engage in prosurvival autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382267
retrieved
31 May 2018
Atg16l1 is required for autophagy in intestinal epithelial cells and protection of mice from Salmonella infection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382267
retrieved
31 May 2018
Overexpression of beclin1 induced autophagy and apoptosis in lungs of K-rasLA1 mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382267
retrieved
31 May 2018
Tyrosine kinase inhibition increases functional parkin-Beclin-1 interaction and enhances amyloid clearance and cognitive performance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382267
retrieved
31 May 2018
Proteomic mapping of mitochondria in living cells via spatially restricted enzymatic tagging.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382267
retrieved
31 May 2018
Pancreatic acinar cell-specific autophagy disruption reduces coxsackievirus replication and pathogenesis in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382267
retrieved
31 May 2018
Insufficient activation of autophagy allows cellular damage to accumulate in critically ill patients
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382267
retrieved
31 May 2018
Differential involvement of Atg16L1 in Crohn disease and canonical autophagy: analysis of the organization of the Atg16L1 complex in fibroblasts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382267
retrieved
31 May 2018
Effect of tolerating macronutrient deficit on the development of intensive-care unit acquired weakness: a subanalysis of the EPaNIC trial.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382267
retrieved
28 November 2018
A dual role for autophagy in a murine model of lung cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382267
retrieved
28 November 2018
Statin therapy reduces the mycobacterium tuberculosis burden in human macrophages and in mice by enhancing autophagy and phagosome maturation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382267
retrieved
28 November 2018
The involvement of autophagy pathway in exaggerated ischemic brain damage in diabetic mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382267
retrieved
28 November 2018
Autophagy is involved in traumatic brain injury-induced cell death and contributes to functional outcome deficits in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382267
retrieved
28 November 2018
Autophagy is required for dietary restriction-mediated life span extension in C. elegans
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382267
retrieved
28 November 2018
Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382267
retrieved
28 November 2018
Autophagy as a basis for the health-promoting effects of vitamin D
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25654546
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1172/JCI73938
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4006082
OpenCitations bibliographic resource ID
4006082
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4006082
PMCID
4382267
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4006082
PubMed ID
25654546
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4006082
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