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Defects in spliceosomal machinery: a new pathway of leukaemogenesis
scientific article
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instance of
scholarly article
2 references
stated in
PubMed
stated in
Europe PubMed Central
PMC publication ID
3507475
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22594801%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
title
Defects in spliceosomal machinery: a new pathway of leukaemogenesis
(English)
2 references
stated in
PubMed
stated in
Europe PubMed Central
PMC publication ID
3507475
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22594801%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
main subject
spliceosome
0 references
author
Richard A Padgett
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
3507475
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22594801%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
Jaroslaw P. Maciejewski
series ordinal
1
object named as
Jaroslaw P Maciejewski
1 reference
stated in
Europe PubMed Central
PMC publication ID
3507475
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22594801%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
language of work or name
English
1 reference
stated in
PubMed
publication date
18 May 2012
1 reference
stated in
Europe PubMed Central
PMC publication ID
3507475
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22594801%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
published in
British Journal of Haematology
2 references
stated in
PubMed
stated in
Europe PubMed Central
PMC publication ID
3507475
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22594801%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
volume
158
2 references
stated in
PubMed
stated in
Europe PubMed Central
PMC publication ID
3507475
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22594801%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
issue
2
2 references
stated in
PubMed
stated in
Europe PubMed Central
PMC publication ID
3507475
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22594801%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
page(s)
165-173
1 reference
stated in
Europe PubMed Central
PMC publication ID
3507475
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22594801%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
cites work
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Splicing of a rare class of introns by the U12-dependent spliceosome
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Manipulation of alternative splicing by a newly developed inhibitor of Clks
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Mammalian polycomb-mediated repression of Hox genes requires the essential spliceosomal protein Sf3b1
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Mutations of the SF3B1 splicing factor in chronic lymphocytic leukemia: association with progression and fludarabine-refractoriness
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Frequent pathway mutations of splicing machinery in myelodysplasia
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Spliceosomal gene mutations are frequent events in the diverse mutational spectrum of chronic myelomonocytic leukemia but largely absent in juvenile myelomonocytic leukemia
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Mutations in the spliceosome machinery, a novel and ubiquitous pathway in leukemogenesis
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Chronic myelomonocytic leukemia and atypical chronic myeloid leukemia: novel pathogenetic lesions
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Recurrent mutations in the U2AF1 splicing factor in myelodysplastic syndromes
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PubMed Central
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28 September 2017
SF3B1 and other novel cancer genes in chronic lymphocytic leukemia
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SF3B1 mutations are prevalent in myelodysplastic syndromes with ring sideroblasts but do not hold independent prognostic value
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AG-dependent 3'-splice sites are predisposed to aberrant splicing due to a mutation at the first nucleotide of an exon.
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PubMed Central
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Meayamycin inhibits pre-messenger RNA splicing and exhibits picomolar activity against multidrug-resistant cells
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Splicing of mRNA precursors: the role of RNAs and proteins in catalysis
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Stalling of spliceosome assembly at distinct stages by small-molecule inhibitors of protein acetylation and deacetylation
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Total syntheses, fragmentation studies, and antitumor/antiproliferative activities of FR901464 and its low picomolar analogue
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RNA interference knockdown of hU2AF35 impairs cell cycle progression and modulates alternative splicing of Cdc25 transcripts
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SAP155 Binds to ceramide-responsive RNA cis-element 1 and regulates the alternative 5' splice site selection of Bcl-x pre-mRNA.
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28 September 2017
Inactivation of the SR protein splicing factor ASF/SF2 results in genomic instability
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Deadly splicing: Bax becomes Almighty
1 reference
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Crossref
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https://api.crossref.org/works/10.1111%2FJ.1365-2141.2012.09158.X
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21 January 2018
Lenalidomide in the myelodysplastic syndrome with chromosome 5q deletion
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1111%2FJ.1365-2141.2012.09158.X
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21 January 2018
Clinical significance of SF3B1 mutations in myelodysplastic syndromes and myelodysplastic/myeloproliferative neoplasms
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1111%2FJ.1365-2141.2012.09158.X
retrieved
21 January 2018
Specific inhibition of serine- and arginine-rich splicing factors phosphorylation, spliceosome assembly, and splicing by the antitumor drug NB-506.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3507475
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28 November 2018
Spliceosomal gene aberrations are rare, coexist with oncogenic mutations, and are unlikely to exert a driver effect in childhood MDS and JMML
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22594801
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
SF3B1, a splicing factor is frequently mutated in refractory anemia with ring sideroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1111%2FJ.1365-2141.2012.09158.X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1111/J.1365-2141.2012.09158.X
1 reference
stated in
Europe PubMed Central
PMC publication ID
3507475
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22594801%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
PMC publication ID
3507475
2 references
stated in
PubMed
stated in
Europe PubMed Central
PMC publication ID
3507475
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22594801%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
PubMed publication ID
22594801
2 references
stated in
PubMed
stated in
Europe PubMed Central
PMC publication ID
3507475
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22594801%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
ResearchGate publication ID
224976719
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