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Could metabolic syndrome lead to hepatocarcinoma via non-alcoholic fatty liver disease?
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scholarly article
1 reference
stated in
PubMed
title
Could metabolic syndrome lead to hepatocarcinoma via non-alcoholic fatty liver disease?
(English)
1 reference
stated in
PubMed
main subject
metabolic syndrome
1 reference
based on heuristic
inferred from title
fatty liver disease
0 references
non-alcoholic fatty liver
1 reference
based on heuristic
inferred from title
metabolic dysfunction–associated steatotic liver disease
1 reference
based on heuristic
inferred from title
author name string
Scalera A
series ordinal
1
1 reference
stated in
PubMed
Tarantino G
series ordinal
2
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stated in
PubMed
language of work or name
English
1 reference
stated in
PubMed
publication date
28 July 2014
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stated in
PubMed
published in
World Journal of Gastroenterology
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stated in
PubMed
volume
20
1 reference
stated in
PubMed
issue
28
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stated in
PubMed
page(s)
9217-28
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stated in
PubMed
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28 September 2017
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What about non-alcoholic fatty liver disease as a new criterion to define metabolic syndrome?
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28 September 2017
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28 September 2017
Diabetes mellitus impacts risk of macrovascular invasion in patients undergoing transplantation for hepatocellular carcinoma
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28 September 2017
Metabolic syndrome and hepatocellular carcinoma risk
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28 September 2017
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Obesity and hepatocellular carcinoma: targeting obesity-related inflammation for chemoprevention of liver carcinogenesis
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Possible role of visfatin in hepatoma progression and the effects of branched-chain amino acids on visfatin-induced proliferation in human hepatoma cells
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28 September 2017
Hepatocellular carcinoma in non-alcoholic steatohepatitis: Growing evidence of an epidemic?
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28 September 2017
Diabetes mellitus and risk of hepatocellular carcinoma: a systematic review and meta-analysis
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28 September 2017
The concept of metabolic syndrome: contribution of visceral fat accumulation and its molecular mechanism
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28 September 2017
Targeting insulin-like growth factor axis in hepatocellular carcinoma
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
IGF activation in a molecular subclass of hepatocellular carcinoma and pre-clinical efficacy of IGF-1R blockage.
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
Adiponectin prevents progression of steatohepatitis in mice by regulating oxidative stress and Kupffer cell phenotype polarization
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28 September 2017
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28 September 2017
Does nonalcoholic fatty liver disease predispose patients to hepatocellular carcinoma in the absence of cirrhosis?
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28 September 2017
Concomitant activation of the JAK/STAT3 and ERK1/2 signaling is involved in leptin-mediated proliferation of renal cell carcinoma Caki-2 cells
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28 September 2017
Hepatocellular carcinoma: management of an increasingly common problem
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Reactivation of the insulin-like growth factor-II signaling pathway in human hepatocellular carcinoma.
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28 September 2017
Potential prognostic value of leptin receptor in hepatocellular carcinoma
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28 September 2017
Potential role of leptin expression in hepatocellular carcinoma
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28 September 2017
The epidemiology of nonalcoholic fatty liver disease in adults
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28 September 2017
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28 September 2017
Suppression of hepatocellular carcinoma growth in mice via leptin, is associated with inhibition of tumor cell growth and natural killer cell activation
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28 September 2017
Peroxisome proliferator-activated receptor gamma inhibition prevents adhesion to the extracellular matrix and induces anoikis in hepatocellular carcinoma cells.
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28 September 2017
Alcohol and hepatocellular carcinoma
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28 September 2017
Leptin as a novel profibrogenic cytokine in hepatic stellate cells: mitogenesis and inhibition of apoptosis mediated by extracellular regulated kinase (Erk) and Akt phosphorylation
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28 September 2017
The weight of leptin in immunity
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28 September 2017
Leptin stimulates tissue inhibitor of metalloproteinase-1 in human hepatic stellate cells: respective roles of the JAK/STAT and JAK-mediated H2O2-dependant MAPK pathways
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28 September 2017
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28 September 2017
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28 September 2017
Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of type 2 diabetes
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110551
retrieved
28 September 2017
Leptin signaling, adiposity, and energy balance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110551
retrieved
28 September 2017
Leptin receptor-mediated signaling regulates hepatic fibrogenesis and remodeling of extracellular matrix in the rat.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110551
retrieved
28 September 2017
Leptin regulation of the immune response and the immunodeficiency of malnutrition
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110551
retrieved
28 September 2017
Peroxisome proliferator-activated receptor gamma and metabolic disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110551
retrieved
28 September 2017
The IGF axis and hepatocarcinogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110551
retrieved
28 September 2017
Peroxisome proliferator-activated receptors: from genes to physiology
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110551
retrieved
28 September 2017
Hepatitis C virus related cirrhosis: time to occurrence of hepatocellular carcinoma and death.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110551
retrieved
28 September 2017
Peroxisome proliferator-activated receptor alpha in metabolic disease, inflammation, atherosclerosis and aging
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110551
retrieved
28 September 2017
Characterization of the insulin-like growth factor axis in a human hepatoma cell line (PLC).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110551
retrieved
28 September 2017
Mitogenic properties of insulin and insulin analogues mediated by the insulin receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110551
retrieved
28 September 2017
Reduced tyrosine kinase activity of the insulin receptor in obesity-diabetes. Central role of tumor necrosis factor-alpha
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110551
retrieved
28 September 2017
Hepatocellular carcinomas in acatalasemic mice treated with nafenopin, a hypolipidemic peroxisome proliferator
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110551
retrieved
28 September 2017
Diabetes mellitus, metabolic syndrome and obesity are not significant risk factors for hepatocellular carcinoma in an HBV- and HCV-endemic area of Southern Taiwan
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110551
retrieved
31 May 2018
PPAR Could Contribute to the Pathogenesis of Hepatocellular Carcinoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110551
retrieved
31 May 2018
Troglitazone inhibits tumor growth in hepatocellular carcinoma in vitro and in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110551
retrieved
31 May 2018
Plasminogen activator inhibitor-1 modulates adipocyte differentiation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110551
retrieved
31 May 2018
Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110551
retrieved
31 May 2018
Obesity and its effect on survival in patients undergoing orthotopic liver transplantation in the United States
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110551
retrieved
31 May 2018
Insulin-like growth factor II (IGF-II) secreted from HepG2 human hepatocellular carcinoma cells shows angiogenic activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110551
retrieved
31 May 2018
A murine model for non-alcoholic steatohepatitis showing evidence of association between diabetes and hepatocellular carcinoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110551
retrieved
28 November 2018
Effect of type 2 diabetes on risk for malignancies includes hepatocellular carcinoma in chronic hepatitis C.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110551
retrieved
28 November 2018
Characteristics of patients with chronic hepatitis C who develop hepatocellular carcinoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110551
retrieved
28 November 2018
Inhibition of autocrine IGF-II on effect of human HepG2 cell proliferation and angiogenesis factor expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110551
retrieved
28 November 2018
Abdominal obesity, weight gain during adulthood and risk of liver and biliary tract cancer in a European cohort
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110551
retrieved
28 November 2018
Diabetes and hepatocellular cancer risk: not only a matter of hyperglycemia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110551
retrieved
28 November 2018
Type 2 diabetes does not worsen prognosis in hepatocellular carcinoma.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110551
retrieved
28 November 2018
Epidemiology of non-alcoholic fatty liver disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110551
retrieved
28 November 2018
The level of fasting serum insulin, but not adiponectin, is associated with the prognosis of early stage hepatocellular carcinoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110551
retrieved
28 November 2018
Adiponectin knockout mice on high fat diet develop fibrosing steatohepatitis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110551
retrieved
28 November 2018
The impact of obesity and diabetes mellitus on the risk of hepatocellular carcinoma.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110551
retrieved
28 November 2018
Body mass index and cancer risk in Korean men and women.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110551
retrieved
28 November 2018
Metabolic factors and risk of hepatocellular carcinoma by chronic hepatitis B/C infection: a follow-up study in Taiwan.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110551
retrieved
28 November 2018
The PPARgamma agonist pioglitazone inhibits early neoplastic occurrence in the rat liver.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110551
retrieved
28 November 2018
Upregulation of proinflammatory and proangiogenic cytokines by leptin in human hepatic stellate cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110551
retrieved
28 November 2018
Hypoadiponectinemia is associated with ischemic cerebrovascular disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110551
retrieved
28 November 2018
Regression analysis of trends in mortality from hepatocellular carcinoma in Japan, 1972-2001.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110551
retrieved
28 November 2018
Serum leptin in NASH correlates with hepatic steatosis but not fibrosis: a manifestation of lipotoxicity?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110551
retrieved
28 November 2018
Diethylnitrosamine induces long-lasting re-expression of insulin-like growth factor II during early stages of liver carcinogenesis in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110551
retrieved
28 November 2018
Trends in mortality from primary liver cancer in Europe
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110551
retrieved
28 November 2018
Inhibitory role of plasminogen activator inhibitor-1 in invasion and proliferation of HLE hepatocellular carcinoma cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110551
retrieved
28 November 2018
Prognosis of chronic hepatitis C: results of a large, prospective cohort study.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110551
retrieved
28 November 2018
Serum adiponectin and leptin levels in relation to the metabolic syndrome, androgenic profile and somatotropic axis in healthy non-diabetic elderly men
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25071314
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Altered transcriptional regulation of the insulin-like growth factor 2 gene in human hepatocellular carcinoma
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25071314
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Insulin resistance is associated with a higher risk of hepatocellular carcinoma in cirrhotic HIV/HCV-co-infected patients: results from ANRS CO13 HEPAVIH
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25071314
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Transcripts of the insulin-like growth factors I and II in human hepatoma
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25071314
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Molecular profiling of human hepatocellular carcinoma defines mutually exclusive interferon regulation and insulin-like growth factor II overexpression
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25071314
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The significance of serum levels of adiponectin, leptin, and hyaluronic acid in hepatocellular carcinoma of cirrhotic and noncirrhotic patients
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25071314
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Hepatitis C infection and the increasing incidence of hepatocellular carcinoma: a population-based study
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25071314
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Central obesity and altered peripheral adipose tissue gene expression characterize the NAFLD patient with insulin resistance: Role of nutrition and insulin challenge
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25071314
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Performance status in patients with hepatocellular carcinoma: determinants, prognostic impact, and ability to improve the Barcelona Clinic Liver Cancer system
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25071314
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Leptin enhances alpha1(I) collagen gene expression in LX-2 human hepatic stellate cells through JAK-mediated H2O2-dependent MAPK pathways
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25071314
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Hepatocellular carcinoma arising from non-cirrhotic nonalcoholic steatohepatitis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25071314
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Diabetes worsens the surgical outcomes in cirrhotic patients with hepatocellular carcinoma
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25071314
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
Fatcat ID
release_dymwbpxflbaj3pze3qqu4gupcu
0 references
OpenCitations bibliographic resource ID
900557
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
900557
PMC publication ID
4110551
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
900557
PubMed publication ID
25071314
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
900557
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