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Steroid receptor coactivators: servants and masters for control of systems metabolism
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title
Steroid receptor coactivators: servants and masters for control of systems metabolism
(English)
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PubMed
author name string
Erin Stashi
series ordinal
1
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stated in
Crossref
Brian York
series ordinal
2
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Crossref
Bert W. O’Malley
series ordinal
3
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stated in
Crossref
language of work or name
English
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PubMed
publication date
July 2014
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stated in
PubMed
published in
Trends in Endocrinology and Metabolism
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stated in
PubMed
volume
25
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stated in
PubMed
issue
7
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PubMed
page(s)
337-47
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PubMed
cites work
Molecular determinants of the interactions between SRC‐1 and LXR/RXR heterodimers
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A map of recent positive selection in the human genome
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PubMed Central
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7 April 2017
The function of TIF2/GRIP1 in mouse reproduction is distinct from those of SRC-1 and p/CIP.
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PubMed Central
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7 April 2017
Nuclear protein CBP is a coactivator for the transcription factor CREB
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PubMed Central
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7 April 2017
The tau 4 activation domain of the thyroid hormone receptor is required for release of a putative corepressor(s) necessary for transcriptional silencing
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PubMed Central
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7 April 2017
Nuclear receptor coregulators: modulators of pathology and therapeutic targets
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7 April 2017
SRC-2 coactivator deficiency decreases functional reserve in response to pressure overload of mouse heart
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PubMed Central
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7 April 2017
Antidiabetic phospholipid–nuclear receptor complex reveals the mechanism for phospholipid-driven gene regulation
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PubMed Central
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7 April 2017
Sequence and characterization of a coactivator for the steroid hormone receptor superfamily
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PubMed Central
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7 April 2017
Xenobiotic induction of cytochrome P450 2B1 (CYP2B1) is mediated by the orphan nuclear receptor constitutive androstane receptor (CAR) and requires steroid co-activator 1 (SRC-1) and the transcription factor Sp1
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108168
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7 April 2017
Fatty-acyl-CoA thioesters inhibit recruitment of steroid receptor co-activator 1 to alpha and gamma isoforms of peroxisome-proliferator-activated receptors by competing with agonists
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PubMed Central
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7 April 2017
Estrogen receptor-associated proteins: possible mediators of hormone-induced transcription
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7 April 2017
A transcriptional co-repressor that interacts with nuclear hormone receptors
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PubMed Central
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7 April 2017
Isolation of coactivators associated with the TATA-binding protein that mediate transcriptional activation
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PubMed Central
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7 April 2017
SRC-2 is an essential coactivator for orchestrating metabolism and circadian rhythm
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108168
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7 April 2017
The steroid receptor coactivator SRC-3 (p/CIP/RAC3/AIB1/ACTR/TRAM-1) is required for normal growth, puberty, female reproductive function, and mammary gland development
1 reference
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PubMed Central
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7 April 2017
Ncoa3 functions as an essential Esrrb coactivator to sustain embryonic stem cell self-renewal and reprogramming
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PubMed Central
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7 April 2017
Aging alters PPARgamma in rodent and human adipose tissue by modulating the balance in steroid receptor coactivator-1
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7 April 2017
Absence of the SRC-2 coactivator results in a glycogenopathy resembling Von Gierke's disease
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PubMed Central
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7 April 2017
AMPK: a nutrient and energy sensor that maintains energy homeostasis
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7 April 2017
Integrative genomic profiling of human prostate cancer
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PubMed Central
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7 April 2017
Steroid receptor coactivator 1 is an integrator of glucose and NAD+/NADH homeostasis
1 reference
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PubMed Central
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28 September 2017
Bufalin is a potent small-molecule inhibitor of the steroid receptor coactivators SRC-3 and SRC-1
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PubMed Central
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28 September 2017
Acceleration of the glycolytic flux by steroid receptor coactivator-2 is essential for endometrial decidualization.
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PubMed Central
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28 September 2017
Nuclear receptor coactivators: master regulators of human health and disease
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PubMed Central
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28 September 2017
Glucocorticoid receptor represses proinflammatory genes at distinct steps of the transcription cycle
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PubMed Central
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28 September 2017
Research resource: loss of the steroid receptor coactivators confers neurobehavioral consequences
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28 September 2017
Differential targeting of brain stress circuits with a selective glucocorticoid receptor modulator.
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28 September 2017
Research resource: tissue- and pathway-specific metabolomic profiles of the steroid receptor coactivator (SRC) family
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28 September 2017
Steroid receptor coactivator-1 mediates estrogenic actions to prevent body weight gain in female mice
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28 September 2017
Mitotane induces CYP3A4 expression via activation of the steroid and xenobiotic receptor.
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PubMed Central
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28 September 2017
Insights into negative regulation by the glucocorticoid receptor from genome-wide profiling of inflammatory cistromes
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28 September 2017
The transcriptional coactivators p/CIP and SRC-1 control insulin resistance through IRS1 in obesity models
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PubMed Central
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28 September 2017
Role of transcriptional coregulator GRIP1 in the anti-inflammatory actions of glucocorticoids.
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28 September 2017
A new isoform of steroid receptor coactivator-1 is crucial for pathogenic progression of endometriosis
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28 September 2017
Ablation of steroid receptor coactivator-3 resembles the human CACT metabolic myopathy
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PubMed Central
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28 September 2017
A Sleeping Beauty mutagenesis screen reveals a tumor suppressor role for Ncoa2/Src-2 in liver cancer.
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28 September 2017
The function of steroid receptor coactivator-1 in normal tissues and cancer
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PubMed Central
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28 September 2017
Small molecule inhibition of the steroid receptor coactivators, SRC-3 and SRC-1.
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28 September 2017
SRC-3 is required for CAR-regulated hepatocyte proliferation and drug metabolism
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28 September 2017
Analysis of the human endogenous coregulator complexome.
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28 September 2017
Homeostatic levels of SRC-2 and SRC-3 promote early human adipogenesis
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28 September 2017
The transcriptional coregulators TIF2 and SRC-1 regulate energy homeostasis by modulating mitochondrial respiration in skeletal muscles
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28 September 2017
Steroid receptor coactivator (SRC) family: masters of systems biology
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28 September 2017
Reprogramming the posttranslational code of SRC-3 confers a switch in mammalian systems biology.
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28 September 2017
A second class of nuclear receptors for oxysterols: Regulation of RORalpha and RORgamma activity by 24S-hydroxycholesterol (cerebrosterol)
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28 September 2017
Peroxisome proliferator-activated receptor gamma coactivator-1alpha interacts with the androgen receptor (AR) and promotes prostate cancer cell growth by activating the AR.
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PubMed Central
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28 September 2017
Normal and cancer-related functions of the p160 steroid receptor co-activator (SRC) family
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PubMed Central
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28 September 2017
Global gene expression profiling in the failing myocardium
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PubMed Central
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28 September 2017
AMPK in Health and Disease
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PubMed Central
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28 September 2017
Loss of steroid receptor co-activator-3 attenuates carbon tetrachloride-induced murine hepatic injury and fibrosis
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PubMed Central
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28 September 2017
Steroid receptor coactivator-1 is necessary for regulation of corticotropin-releasing hormone by chronic stress and glucocorticoids.
1 reference
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PubMed Central
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28 September 2017
The steroid receptor coactivator-1 regulates twist expression and promotes breast cancer metastasis
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PubMed Central
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28 September 2017
PIASy inhibits LRH-1-dependent CYP11A1 expression by competing for SRC-1 binding
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108168
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28 September 2017
The genetic ablation of SRC-3 protects against obesity and improves insulin sensitivity by reducing the acetylation of PGC-1{alpha}.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108168
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28 September 2017
CYP2B6: new insights into a historically overlooked cytochrome P450 isozyme
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108168
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28 September 2017
Modulation of hepatocyte nuclear factor-4alpha function by the peroxisome-proliferator-activated receptor-gamma co-activator-1alpha in the acute-phase response.
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PubMed Central
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28 September 2017
Steroid receptor coactivator 3 maintains circulating insulin-like growth factor I (IGF-I) by controlling IGF-binding protein 3 expression
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108168
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28 September 2017
Coregulators: from whence came these "master genes".
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28 September 2017
Tumor necrosis factor and interleukin 1 decrease RXRalpha, PPARalpha, PPARgamma, LXRalpha, and the coactivators SRC-1, PGC-1alpha, and PGC-1beta in liver cells
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PubMed Central
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28 September 2017
Steroid receptor coactivator-3 and activator protein-1 coordinately regulate the transcription of components of the insulin-like growth factor/AKT signaling pathway
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108168
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28 September 2017
Underexpressed coactivators PGC1alpha and SRC1 impair hepatocyte nuclear factor 4 alpha function and promote dedifferentiation in human hepatoma cells.
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PubMed Central
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28 September 2017
Steroid receptor coactivator-1-deficient mice exhibit altered hypothalamic-pituitary-adrenal axis function
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PubMed Central
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28 September 2017
Downregulation of liver X receptor-alpha in mouse kidney and HK-2 proximal tubular cells by LPS and cytokines
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PubMed Central
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28 September 2017
Molecular mechanism for the potentiation of the transcriptional activity of human liver receptor homolog 1 by steroid receptor coactivator-1.
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PubMed Central
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28 September 2017
Ligand-dependent contribution of RXRbeta to cholesterol homeostasis in Sertoli cells.
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28 September 2017
Role of the estrogen receptor coactivator AIB1 (SRC-3) and HER-2/neu in tamoxifen resistance in breast cancer
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PubMed Central
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28 September 2017
Progesterone-binding components of chick oviduct. 3. Chromatin acceptor sites.
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28 September 2017
The mechanism of RU486 antagonism is dependent on the conformation of the carboxy-terminal tail of the human progesterone receptor
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28 September 2017
Identification of a negative regulatory function for steroid receptors
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28 September 2017
A novel B cell-derived coactivator potentiates the activation of immunoglobulin promoters by octamer-binding transcription factors
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28 September 2017
Hormone and antihormone induce distinct conformational changes which are central to steroid receptor activation
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28 September 2017
Cellular energy depletion resets whole-body energy by promoting coactivator-mediated dietary fuel absorption.
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31 May 2018
Critical roles of the p160 transcriptional coactivators p/CIP and SRC-1 in energy balance
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31 May 2018
Polarity-specific activities of retinoic acid receptors determined by a co-repressor.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108168
retrieved
31 May 2018
AIB1 shows variation in interaction with ERβTAD and expression as a function of age in mouse brain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108168
retrieved
28 November 2018
The coactivator SRC-1 is an essential coordinator of hepatic glucose production.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108168
retrieved
28 November 2018
Insidious adrenocortical insufficiency underlies neuroendocrine dysregulation in TIF-2 deficient mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108168
retrieved
28 November 2018
Steroid receptor coactivator-3 is required for progesterone receptor trans-activation of target genes in response to gonadotropin-releasing hormone treatment of pituitary cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108168
retrieved
28 November 2018
The genomic analysis of the impact of steroid receptor coactivators ablation on hepatic metabolism.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108168
retrieved
28 November 2018
Deletion of steroid receptor coactivator-3 gene ameliorates hepatic steatosis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24953190
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Transcriptional activation of CYP2C9, CYP1A1, and CYP1A2 by hepatocyte nuclear factor 4alpha requires coactivators peroxisomal proliferator activated receptor-gamma coactivator 1alpha and steroid receptor coactivator 1
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24953190
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
SRC-1 and TIF2 control energy balance between white and brown adipose tissues
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24953190
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Converting a eukaryotic transcriptional inhibitor into an activator
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24953190
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identification of nuclear factors that enhance binding of the thyroid hormone receptor to a thyroid hormone response element
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24953190
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Transcriptional Activation of CYP2C9, CYP1A1, and CYP1A2 by Hepatocyte Nuclear Factor 4 Requires Coactivators Peroxisomal Proliferator Activated Receptor- Coactivator 1 and Steroid Receptor Coactivator 1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.TEM.2014.05.004
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/J.TEM.2014.05.004
0 references
PMC publication ID
4108168
1 reference
stated in
PubMed
PubMed publication ID
24953190
1 reference
stated in
PubMed
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