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Dendrimer advances for the central nervous system delivery of therapeutics
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PubMed
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Europe PubMed Central
PMC publication ID
3894720
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24274162%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
title
Dendrimer advances for the central nervous system delivery of therapeutics
(English)
2 references
stated in
PubMed
stated in
Europe PubMed Central
PMC publication ID
3894720
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24274162%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
main subject
nervous system
0 references
author
Leyuan Xu
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
3894720
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24274162%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
author name string
Hao Zhang
series ordinal
2
2 references
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Crossref
stated in
Europe PubMed Central
PMC publication ID
3894720
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24274162%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
Yue Wu
series ordinal
3
2 references
stated in
Crossref
stated in
Europe PubMed Central
PMC publication ID
3894720
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24274162%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
language of work or name
English
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publication date
5 December 2013
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Europe PubMed Central
PMC publication ID
3894720
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24274162%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
published in
ACS Chemical Neuroscience
2 references
stated in
Crossref
stated in
Europe PubMed Central
PMC publication ID
3894720
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24274162%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
volume
5
2 references
stated in
PubMed
stated in
Europe PubMed Central
PMC publication ID
3894720
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24274162%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
issue
1
2 references
stated in
PubMed
stated in
Europe PubMed Central
PMC publication ID
3894720
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24274162%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
page(s)
2-13
2 references
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PubMed
stated in
Europe PubMed Central
PMC publication ID
3894720
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24274162%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
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Doxorubicin delivery by polyamidoamine dendrimer conjugation and photochemical internalization for cancer therapy
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Blood-brain barrier transport of therapeutics via receptor-mediation
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28 September 2017
Attenuation of beta-amyloid-induced toxicity by sialic-acid-conjugated dendrimers: role of sialic acid attachment
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Transvascular delivery of small interfering RNA to the central nervous system.
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Genetic engineering, expression, and activity of a fusion protein of a human neurotrophin and a molecular Trojan horse for delivery across the human blood-brain barrier
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28 September 2017
Efficient gene delivery targeted to the brain using a transferrin-conjugated polyethyleneglycol-modified polyamidoamine dendrimer
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28 September 2017
Attenuation of beta-amyloid induced toxicity by sialic acid-conjugated dendrimeric polymers
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894720
retrieved
28 September 2017
In vivo imaging of the diseased nervous system
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894720
retrieved
28 September 2017
A review of nanocarrier-based CNS delivery systems
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894720
retrieved
28 September 2017
Dendrimer biocompatibility and toxicity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894720
retrieved
28 September 2017
Preparation, cellular transport, and activity of polyamidoamine-based dendritic nanodevices with a high drug payload
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894720
retrieved
28 September 2017
Design and development of polymers for gene delivery
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894720
retrieved
28 September 2017
Light-mediated inhibition of protein synthesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894720
retrieved
28 September 2017
Tumor imaging by means of proteolytic activation of cell-penetrating peptides
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894720
retrieved
28 September 2017
Enhanced transfection efficiency of PAMAM dendrimer by surface modification with L-arginine
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894720
retrieved
28 September 2017
Developmentally regulated mannose 6-phosphate receptor-mediated transport of a lysosomal enzyme across the blood-brain barrier
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894720
retrieved
28 September 2017
Boronated epidermal growth factor as a delivery agent for neutron capture therapy of EGF receptor positive gliomas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894720
retrieved
28 September 2017
Cytotoxicity, hemolysis, and acute in vivo toxicity of dendrimers based on melamine, candidate vehicles for drug delivery
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894720
retrieved
28 September 2017
Polyplexes assembled with internally quaternized PAMAM-OH dendrimer and plasmid DNA have a neutral surface and gene delivery potency.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894720
retrieved
28 September 2017
Holey barrier: claudins and the regulation of brain endothelial permeability
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894720
retrieved
28 September 2017
In vitro cytotoxicity testing of polycations: influence of polymer structure on cell viability and hemolysis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894720
retrieved
28 September 2017
Drug and gene delivery to the brain: the vascular route
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894720
retrieved
28 September 2017
Antisense imaging of gene expression in the brain in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894720
retrieved
28 September 2017
Dendrimers: relationship between structure and biocompatibility in vitro, and preliminary studies on the biodistribution of 125I-labelled polyamidoamine dendrimers in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894720
retrieved
28 September 2017
A novel non-viral vector for DNA delivery based on low molecular weight, branched polyethylenimine: effect of molecular weight on transfection efficiency and cytotoxicity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894720
retrieved
28 September 2017
Brominated 7-hydroxycoumarin-4-ylmethyls: photolabile protecting groups with biologically useful cross-sections for two photon photolysis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894720
retrieved
28 September 2017
Drug targeting of a peptide radiopharmaceutical through the primate blood-brain barrier in vivo with a monoclonal antibody to the human insulin receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894720
retrieved
28 September 2017
Preliminary biological evaluation of polyamidoamine (PAMAM) Starburst dendrimers
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894720
retrieved
28 September 2017
Expression and function of the low density lipoprotein receptor-related protein (LRP) in mammalian central neurons.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894720
retrieved
28 September 2017
Anti-transferrin receptor antibody and antibody-drug conjugates cross the blood-brain barrier
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894720
retrieved
28 September 2017
Boronated epidermal growth factor as a potential targeting agent for boron neutron capture therapy of brain tumors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894720
retrieved
28 September 2017
Dendrimer-triglycine-EGF nanoparticles for tumor imaging and targeted nucleic acid and drug delivery
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894720
retrieved
31 May 2018
Relationship between permeability status of the blood-brain barrier and in vitro permeability coefficient of a drug
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894720
retrieved
31 May 2018
Cerebrovascular permeability coefficients to sodium, potassium, and chloride
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894720
retrieved
31 May 2018
Effect of poly(propylene imine) glycodendrimers on beta-amyloid aggregation in vitro and in APP/PS1 transgenic mice, as a model of brain amyloid deposition and Alzheimer's disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894720
retrieved
28 November 2018
Ultra-sensitive molecular MRI of cerebrovascular cell activation enables early detection of chronic central nervous system disorders.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894720
retrieved
28 November 2018
A brain-vectored angiopep-2 based polymeric micelles for the treatment of intracranial fungal infection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894720
retrieved
28 November 2018
Enhanced brain delivery of liposomal methylprednisolone improved therapeutic efficacy in a model of neuroinflammation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894720
retrieved
28 November 2018
Gene delivery targeted to the brain using an Angiopep-conjugated polyethyleneglycol-modified polyamidoamine dendrimer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894720
retrieved
28 November 2018
Ligands for mapping alphavbeta3-integrin expression in vivo.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894720
retrieved
28 November 2018
Brain-targeting gene delivery and cellular internalization mechanisms for modified rabies virus glycoprotein RVG29 nanoparticles
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894720
retrieved
28 November 2018
Quantum dots bearing lectin-functionalized nanoparticles as a platform for in vivo brain imaging
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894720
retrieved
28 November 2018
Tf-lipoplexes for neuronal siRNA delivery: a promising system to mediate gene silencing in the CNS.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894720
retrieved
28 November 2018
Potential of poly(amidoamine) dendrimers as drug carriers of camptothecin based on encapsulation studies.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894720
retrieved
28 November 2018
Identification and design of peptides as a new drug delivery system for the brain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894720
retrieved
28 November 2018
The use of lactoferrin as a ligand for targeting the polyamidoamine-based gene delivery system to the brain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894720
retrieved
28 November 2018
EPR study of the interactions between dendrimers and peptides involved in Alzheimer's and prion diseases.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894720
retrieved
28 November 2018
Covalent linkage of apolipoprotein e to albumin nanoparticles strongly enhances drug transport into the brain.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894720
retrieved
28 November 2018
Tissue-type plasminogen activator crosses the intact blood-brain barrier by low-density lipoprotein receptor-related protein-mediated transcytosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894720
retrieved
28 November 2018
Chloride accumulation and swelling in endosomes enhances DNA transfer by polyamine-DNA polyplexes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894720
retrieved
28 November 2018
Polyethylene glycol modified polyethylenimine for improved CNS gene transfer: effects of PEGylation extent
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894720
retrieved
28 November 2018
Direct evidence that polysorbate-80-coated poly(butylcyanoacrylate) nanoparticles deliver drugs to the CNS via specific mechanisms requiring prior binding of drug to the nanoparticles
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894720
retrieved
28 November 2018
Global non-viral gene transfer to the primate brain following intravenous administration
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894720
retrieved
28 November 2018
Drug pH-sensitive release in vitro and targeting ability of polyamidoamine dendrimer complexes for tumor cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24274162
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
CNS disorders--current treatment options and the prospects for advanced therapies
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24274162
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Effect of peptidases at the blood brain barrier on the permeability of enkephalin
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24274162
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Targeting anti-transferrin receptor antibody (OX26) and OX26-conjugated liposomes to brain capillary endothelial cells using in situ perfusion
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24274162
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1021/CN400182Z
1 reference
stated in
Europe PubMed Central
PMC publication ID
3894720
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24274162%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
PMC publication ID
3894720
2 references
stated in
PubMed
stated in
Europe PubMed Central
PMC publication ID
3894720
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24274162%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
PubMed publication ID
24274162
2 references
stated in
PubMed
stated in
Europe PubMed Central
PMC publication ID
3894720
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24274162%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
ResearchGate publication ID
258920857
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