(Q26828495)

Nobunari Sasaki

series ordinal

2

1 reference

Shunsuke Kitajima

series ordinal

3

1 reference

language of work or name

1 reference

July 2012

1 reference

1 reference

103

1 reference

issue

7

1 reference

page(s)

1182-8

1 reference

Retinoblastoma family proteins: insights gained through genetic manipulation of mice

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Cellular mechanisms of tumour suppression by the retinoblastoma gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Newly identified aspects of tumor suppression by RB

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

The retinoblastoma protein is required for Ras-induced oncogenic transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Phosphorylation of pRB at Ser612 by Chk1/2 leads to a complex between pRB and E2F-1 after DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

AMP-activated protein kinase phosphorylates retinoblastoma protein to control mammalian brain development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Mitochondrial stress engages E2F1 apoptotic signaling to cause deafness

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Oxidative stress induces protein phosphatase 2A-dependent dephosphorylation of the pocket proteins pRb, p107, and p130.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Rb Regulates DNA damage response and cellular senescence through E2F-dependent suppression of N-ras isoprenylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Deacetylation of the retinoblastoma tumour suppressor protein by SIRT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Viral oncoproteins E1A and E7 and cellular LxCxE proteins repress SUMO modification of the retinoblastoma tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Enhanced Mdm2 activity inhibits pRB function via ubiquitin-dependent degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Apoptotic caspases regulate induction of iPSCs from human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Stable binding to E2F is not required for the retinoblastoma protein to activate transcription, promote differentiation, and suppress tumor cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Skp2 is required for survival of aberrantly proliferating Rb1-deficient cells and for tumorigenesis in Rb1+/- mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Cells degrade a novel inhibitor of differentiation with E1A-like properties upon exiting the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

A novel Rb- and p300-binding protein inhibits transactivation by MyoD

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Binding of pRB to the PHD protein RBP2 promotes cellular differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Structure-function analysis of the retinoblastoma tumor suppressor protein - is the whole a sum of its parts?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Cell cycle-dependent activation of Ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

lin-35 and lin-53, two genes that antagonize a C. elegans Ras pathway, encode proteins similar to Rb and its binding protein RbAp48.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

The retinoblastoma protein is linked to the activation of Ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Genetic interaction between Rb and N-ras: differentiation control and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Rb and N-ras function together to control differentiation in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Genetic interaction between Rb and K-ras in the control of differentiation and tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Inactivation of the p53 pathway in retinoblastoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Loss of RB1 induces non-proliferative retinoma: increasing genomic instability correlates with progression to retinoblastoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Mutation of the Rb1 pathway leads to overexpression of mTor, constitutive phosphorylation of Akt on serine 473, resistance to anoikis, and a block in c-Raf activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Specific killing of Rb mutant cancer cells by inactivating TSC2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Cyclins, Cdks, E2f, Skp2, and more at the first international RB Tumor Suppressor Meeting.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Involvement of RB gene family in tumor angiogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Abrogated response to cellular stress identifies DCIS associated with subsequent tumor events and defines basal-like breast tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

SREBPs: metabolic integrators in physiology and metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

The Akt-SREBP nexus: cell signaling meets lipid metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

ROS-mediated p53 induction of Lpin1 regulates fatty acid oxidation in response to nutritional stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Regulation of cancer cell metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

An E2F1-dependent gene expression program that determines the balance between proliferation and cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

The LKB1-AMPK pathway: metabolism and growth control in tumour suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

New users of metformin are at low risk of incident cancer: a cohort study among people with type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Rb intrinsically promotes erythropoiesis by coupling cell cycle exit with mitochondrial biogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Rescue of myogenic defects in Rb-deficient cells by inhibition of autophagy or by hypoxia-induced glycolytic shift

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

BNIP3 is an RB/E2F target gene required for hypoxia-induced autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Genome-wide analysis of the H3K4 histone demethylase RBP2 reveals a transcriptional program controlling differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

E2F transcription factor-1 regulates oxidative metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

The role of the RB tumour suppressor pathway in oxidative stress responses in the haematopoietic system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

pRB, a tumor suppressor with a stabilizing presence

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Nucleotide deficiency promotes genomic instability in early stages of cancer development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Mad2-induced chromosome instability leads to lung tumour relapse after oncogene withdrawal

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Rb regulates fate choice and lineage commitment in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Rb deletion in mouse mammary progenitors induces luminal-B or basal-like/EMT tumor subtypes depending on p53 status

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

A functional role for tumor cell heterogeneity in a mouse model of small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Extra-embryonic function of Rb is essential for embryonic development and viability

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Rb regulates interactions between hematopoietic stem cells and their bone marrow microenvironment

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Plant retinoblastoma homologues control nuclear proliferation in the female gametophyte

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Deconstructing stem cell self-renewal: genetic insights into cell-cycle regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Monitoring early differentiation events in human embryonic stem cells by massively parallel signature sequencing and expressed sequence tag scan.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Keeping an eye on retinoblastoma control of human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Suppression of induced pluripotent stem cell generation by the p53-p21 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Mitochondrial metabolism modulates differentiation and teratoma formation capacity in mouse embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

A Myc network accounts for similarities between embryonic stem and cancer cell transcription programs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Mouse fibroblasts lacking RB1 function form spheres and undergo reprogramming to a cancer stem cell phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Nanog transforms NIH3T3 cells and targets cell-type restricted genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Nanog-induced dedifferentiation of p53-deficient mouse astrocytes into brain cancer stem-like cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Functional evidence that the self-renewal gene NANOG regulates human tumor development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Proliferation of functional hair cells in vivo in the absence of the retinoblastoma protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

The retinoblastoma gene pathway regulates the postmitotic state of hair cells of the mouse inner ear.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Transient inactivation of Rb and ARF yields regenerative cells from postmitotic mammalian muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Differentiated horizontal interneurons clonally expand to form metastatic retinoblastoma in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

The RETINOBLASTOMA-RELATED Gene Regulates Stem Cell Maintenance in Arabidopsis Roots

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02284.X

Retinoblastoma regulatory pathway in lung cancer

21 January 2018

1 reference

12 December 2020

Cellular ras gene activity is required for full neoplastic transformation by the large tumor antigen of SV40.

1 reference

12 December 2020

A novel retinoblastoma therapy from genomic and epigenetic analyses

1 reference

12 December 2020

Nras loss induces metastatic conversion of Rb1-deficient neuroendocrine thyroid tumor

1 reference

12 December 2020