(Q42614170)

English

Mutation of the Rb1 pathway leads to overexpression of mTor, constitutive phosphorylation of Akt on serine 473, resistance to anoikis, and a block in c-Raf activation

scientific article published on 24 August 2009

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

3 November 2017

Mutation of the Rb1 pathway leads to overexpression of mTor, constitutive phosphorylation of Akt on serine 473, resistance to anoikis, and a block in c-Raf activation (English)

1 reference

Europe PubMed Central

PMC publication ID

3 November 2017

1 reference

based on heuristic

inferred from title

phosphorylation

1 reference

based on heuristic

inferred from title

author name string

Shahenda El-Naggar

1

1 reference

Europe PubMed Central

PMC publication ID

3 November 2017

Yongqing Liu

2

1 reference

Europe PubMed Central

PMC publication ID

3 November 2017

Douglas C Dean

3

1 reference

Europe PubMed Central

PMC publication ID

3 November 2017

language of work or name

0 references

publication date

24 August 2009

1 reference

Europe PubMed Central

PMC publication ID

3 November 2017

Molecular and Cellular Biology

1 reference

Europe PubMed Central

PMC publication ID

3 November 2017

29

1 reference

Europe PubMed Central

PMC publication ID

3 November 2017

21

1 reference

Europe PubMed Central

PMC publication ID

3 November 2017

5710-5717

1 reference

Europe PubMed Central

PMC publication ID

3 November 2017

mTOR complex 2 is required for the development of prostate cancer induced by Pten loss in mice

1 reference

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27 May 2018

PI3K/Akt: getting it right matters

1 reference

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27 May 2018

Metastasis and AKT activation

1 reference

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27 May 2018

The PTEN-PI3K pathway: of feedbacks and cross-talks

1 reference

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27 May 2018

Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signalling

1 reference

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27 May 2018

The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C

1 reference

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27 May 2018

E1a gene expression blocks the ERK1/2 signaling pathway by promoting nuclear localization and MKP up-regulation: implication in v-H-Ras-induced senescence

1 reference

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Zeb1 links epithelial-mesenchymal transition and cellular senescence

1 reference

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Dynamic FoxO transcription factors

1 reference

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27 May 2018

Loss of PTEN selectively desensitizes upstream IGF1 and insulin signaling.

1 reference

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27 May 2018

The two TORCs and Akt.

1 reference

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27 May 2018

Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1

1 reference

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27 May 2018

Identification of Sin1 as an essential TORC2 component required for complex formation and kinase activity

1 reference

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27 May 2018

Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability

1 reference

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27 May 2018

SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772742

27 May 2018

mTOR and cancer: insights into a complex relationship

1 reference

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27 May 2018

Ras transformation requires metabolic control by 6-phosphofructo-2-kinase

1 reference

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27 May 2018

Identification of a tumour suppressor network opposing nuclear Akt function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772742

27 May 2018

TOR signaling in growth and metabolism

1 reference

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27 May 2018

Reduction in the requirement of oncogenic Ras signaling to activation of PI3K/AKT pathway during tumor maintenance

1 reference

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27 May 2018

Targeting BACE1 with siRNAs ameliorates Alzheimer disease neuropathology in a transgenic model

1 reference

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27 May 2018

Signaling interplay in Ras superfamily function

1 reference

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27 May 2018

Upstream and downstream of mTOR

1 reference

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27 May 2018

Mutually exclusive mutations of the Pten and ras pathways in skin tumor progression

1 reference

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27 May 2018

In vivo role of the PIF-binding docking site of PDK1 defined by knock-in mutation

1 reference

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27 May 2018

Tumor suppression by Ink4a-Arf: progress and puzzles

1 reference

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27 May 2018

Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control

1 reference

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27 May 2018

Tangled webs: evidence of cross-talk between c-Raf-1 and Akt.

1 reference

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27 May 2018

Anoikis mechanisms

1 reference

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Ablation of the retinoblastoma gene family deregulates G(1) control causing immortalization and increased cell turnover under growth-restricting conditions

1 reference

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27 May 2018

Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization

1 reference

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27 May 2018

The Rb/E2F pathway: expanding roles and emerging paradigms

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Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

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Identification of c-MYC as a target of the APC pathway

1 reference

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27 May 2018

Mechanism of activation of protein kinase B by insulin and IGF-1

1 reference

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27 May 2018

1 reference

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27 May 2018

Lack of cytoplasmic ERK activation is an independent adverse prognostic factor in primary cutaneous melanoma

1 reference

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16 August 2018

Design and cloning of lentiviral vectors expressing small interfering RNAs

1 reference

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16 August 2018

PTEN loss promotes rasHa-mediated papillomatogenesis via dual up-regulation of AKT activity and cell cycle deregulation but malignant conversion proceeds via PTEN-associated pathways

1 reference

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16 August 2018

Loss of Rb overrides the requirement for ERK activity for cell proliferation

1 reference

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16 August 2018

Identifiers

10.1128/MCB.00197-09

1 reference

Europe PubMed Central

PMC publication ID

3 November 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

3 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

3 November 2017

ResearchGate publication ID

0 references

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