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A Blueprint for HIV Vaccine Discovery
scientific article
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scholarly article
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stated in
PubMed
title
A Blueprint for HIV Vaccine Discovery
(English)
1 reference
stated in
PubMed
main subject
vaccine
1 reference
based on heuristic
inferred from title
HIV
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author
Adam Godzik
series ordinal
6
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Hendrik Streeck
series ordinal
14
object named as
Hendrik Streeck
1 reference
stated in
Crossref
Bali Pulendran
series ordinal
10
object named as
Bali Pulendran
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stated in
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Rafi Ahmed
series ordinal
2
object named as
Rafi Ahmed
1 reference
stated in
Crossref
Shane Crotty
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5
object named as
Shane Crotty
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Richard T. Wyatt
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19
object named as
Richard Wyatt
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Guido Silvestri
series ordinal
13
object named as
Guido Silvestri
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Michel C. Nussenzweig
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9
object named as
Michel C. Nussenzweig
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Daniel E Kaufmann
series ordinal
7
object named as
Daniel E. Kaufmann
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William R Schief
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12
object named as
William R. Schief
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author name string
Dennis R. Burton
series ordinal
1
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Dan H. Barouch
series ordinal
3
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Salvatore T. Butera
series ordinal
4
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M. Juliana McElrath
series ordinal
8
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Chris N. Scanlan
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11
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Bruce D. Walker
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15
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Laura M. Walker
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16
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Andrew B. Ward
series ordinal
17
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Ian A. Wilson
series ordinal
18
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language of work or name
English
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PubMed
publication date
18 October 2012
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stated in
PubMed
published in
Cell Host & Microbe
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stated in
PubMed
volume
12
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stated in
PubMed
issue
4
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stated in
PubMed
page(s)
396-407
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PubMed
cites work
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Crystal structure of HIV-1 gp41 including both fusion peptide and membrane proximal external regions
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7 April 2017
The hope for an HIV vaccine based on induction of CD8+ T lymphocytes--a review
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7 April 2017
Structural definition of a conserved neutralization epitope on HIV-1 gp120
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7 April 2017
Antibody vs. HIV in a clash of evolutionary titans
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7 April 2017
The Antibody Response against HIV-1
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7 April 2017
Broad and potent neutralization of HIV-1 by a gp41-specific human antibody
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7 April 2017
Computation-guided backbone grafting of a discontinuous motif onto a protein scaffold
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7 April 2017
A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield
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7 April 2017
Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing
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7 April 2017
Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding
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7 April 2017
Design and Characterization of Epitope-Scaffold Immunogens That Present the Motavizumab Epitope from Respiratory Syncytial Virus
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7 April 2017
Elicitation of structure-specific antibodies by epitope scaffolds
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7 April 2017
Computational design of epitope-scaffolds allows induction of antibodies specific for a poorly immunogenic HIV vaccine epitope
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7 April 2017
Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01
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7 April 2017
Structural Basis of Immune Evasion at the Site of CD4 Attachment on HIV-1 gp120
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PubMed Central
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7 April 2017
Molecular architecture of native HIV-1 gp120 trimers
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PubMed Central
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7 April 2017
Antibody domain exchange is an immunological solution to carbohydrate cluster recognition
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PubMed Central
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7 April 2017
B cell follicles and antigen encounters of the third kind
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PubMed Central
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7 April 2017
Phosphoinositide 3-kinase activity in T cells regulates the magnitude of the germinal center reaction
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7 April 2017
Bcl6 mediates the development of T follicular helper cells
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7 April 2017
Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation
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PubMed Central
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7 April 2017
GP120: target for neutralizing HIV-1 antibodies
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7 April 2017
Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target
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7 April 2017
Broad neutralization coverage of HIV by multiple highly potent antibodies
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7 April 2017
Follicular helper CD4 T cells (TFH)
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7 April 2017
Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1
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7 April 2017
Systems biology approach predicts immunogenicity of the yellow fever vaccine in humans
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7 April 2017
Human immunodeficiency virus type 1 env clones from acute and early subtype B infections for standardized assessments of vaccine-elicited neutralizing antibodies
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7 April 2017
The HIV-1 Envelope Glycoproteins: Fusogens, Antigens, and Immunogens
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7 April 2017
Antigenicity and Immunogenicity in HIV-1 Antibody-Based Vaccine Design
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28 September 2017
Innate immune sensing of HIV-1 by dendritic cells
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PubMed Central
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28 September 2017
Expansion of HIV-specific T follicular helper cells in chronic HIV infection
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PubMed Central
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28 September 2017
CD4 T follicular helper cell dynamics during SIV infection
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PubMed Central
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28 September 2017
Subunit organization of the membrane-bound HIV-1 envelope glycoprotein trimer
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PubMed Central
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28 September 2017
Broad neutralization by a combination of antibodies recognizing the CD4 binding site and a new conformational epitope on the HIV-1 envelope protein
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28 September 2017
Broadly neutralizing antibodies present new prospects to counter highly antigenically diverse viruses
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28 September 2017
The changing face of HIV vaccine research
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28 September 2017
Structural basis for germ-line gene usage of a potent class of antibodies targeting the CD4-binding site of HIV-1 gp120.
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28 September 2017
B-cell-lineage immunogen design in vaccine development with HIV-1 as a case study
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28 September 2017
The 1-1-1 fallacy
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28 September 2017
PGV04, an HIV-1 gp120 CD4 binding site antibody, is broad and potent in neutralization but does not induce conformational changes characteristic of CD4.
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28 September 2017
Rational design of vaccines to elicit broadly neutralizing antibodies to HIV-1.
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28 September 2017
Vaccine protection against acquisition of neutralization-resistant SIV challenges in rhesus monkeys
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28 September 2017
Longitudinal analysis of early HIV-1-specific neutralizing activity in an elite neutralizer and in five patients who developed cross-reactive neutralizing activity
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28 September 2017
Prospects for an HIV vaccine: leading B cells down the right path
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28 September 2017
Rapid development of glycan-specific, broad, and potent anti-HIV-1 gp120 neutralizing antibodies in an R5 SIV/HIV chimeric virus infected macaque
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28 September 2017
Isolation of a human anti-HIV gp41 membrane proximal region neutralizing antibody by antigen-specific single B cell sorting
1 reference
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PubMed Central
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28 September 2017
Cross-reactive HIV-1-neutralizing human monoclonal antibodies identified from a patient with 2F5-like antibodies
1 reference
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PubMed Central
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28 September 2017
The glycan shield of HIV is predominantly oligomannose independently of production system or viral clade.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3513329
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28 September 2017
Occluding the mannose moieties on human immunodeficiency virus type 1 gp120 with griffithsin improves the antibody responses to both proteins in mice.
1 reference
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PubMed Central
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28 September 2017
Cutting edge: dendritic cell-restricted antigen presentation initiates the follicular helper T cell program but cannot complete ultimate effector differentiation
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28 September 2017
Coordinate linkage of HIV evolution reveals regions of immunological vulnerability
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28 September 2017
Characterization of glycosylation profiles of HIV-1 transmitted/founder envelopes by mass spectrometry
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PubMed Central
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28 September 2017
Inhibition of HIV transmission in human cervicovaginal explants and humanized mice using CD4 aptamer-siRNA chimeras
1 reference
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28 September 2017
Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine
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28 September 2017
CD4+ T cells support cytotoxic T lymphocyte priming by controlling lymph node input.
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28 September 2017
Role of immune mechanisms in induction of HIV-1 broadly neutralizing antibodies
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3513329
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28 September 2017
Comparison of antibody repertoires produced by HIV-1 infection, other chronic and acute infections, and systemic autoimmune disease
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28 September 2017
Enzyme digests eliminate nonfunctional Env from HIV-1 particle surfaces, leaving native Env trimers intact and viral infectivity unaffected
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28 September 2017
The neutralization breadth of HIV-1 develops incrementally over four years and is associated with CD4+ T cell decline and high viral load during acute infection
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28 September 2017
Potent and broad neutralization of HIV-1 subtype C by plasma antibodies targeting a quaternary epitope including residues in the V2 loop
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28 September 2017
Characteristics of the earliest cross-neutralizing antibody response to HIV-1.
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28 September 2017
Trafficking of B cell antigen in lymph nodes.
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28 September 2017
Contributions of humoral and cellular immunity to vaccine-induced protection in humans.
1 reference
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retrieved
28 September 2017
Germinal center dynamics revealed by multiphoton microscopy with a photoactivatable fluorescent reporter
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3513329
retrieved
28 September 2017
HIV-1 superinfection and its implications for vaccine design
1 reference
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PubMed Central
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28 September 2017
Early events in sexual transmission of HIV and SIV and opportunities for interventions
1 reference
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PubMed Central
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28 September 2017
Induction of immunity to human immunodeficiency virus type-1 by vaccination
1 reference
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3513329
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28 September 2017
In vivo mechanisms of vaccine-induced protection against HPV infection
1 reference
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28 September 2017
A limited number of antibody specificities mediate broad and potent serum neutralization in selected HIV-1 infected individuals
1 reference
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PubMed Central
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28 September 2017
Envelope glycans of immunodeficiency virions are almost entirely oligomannose antigens.
1 reference
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PubMed Central
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28 September 2017
Correlates of protection induced by vaccination
1 reference
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28 September 2017
Glycosylation patterns of HIV-1 gp120 depend on the type of expressing cells and affect antibody recognition.
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28 September 2017
Lack of complex N-glycans on HIV-1 envelope glycoproteins preserves protein conformation and entry function
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28 September 2017
Rational antibody-based HIV-1 vaccine design: current approaches and future directions
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28 September 2017
Targeting early infection to prevent HIV-1 mucosal transmission.
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28 September 2017
The role of antibodies in HIV vaccines
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28 September 2017
Analysis of memory B cell responses and isolation of novel monoclonal antibodies with neutralizing breadth from HIV-1-infected individuals
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28 September 2017
HIV-1 vaccine development after STEP.
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28 September 2017
Challenges for structure-based HIV vaccine design
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28 September 2017
Immunogenicity of HIV-1 envelope glycoprotein oligomers
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28 September 2017
Breadth of human immunodeficiency virus-specific neutralizing activity in sera: clustering analysis and association with clinical variables
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28 September 2017
Germline-like predecessors of broadly neutralizing antibodies lack measurable binding to HIV-1 envelope glycoproteins: implications for evasion of immune responses and design of vaccine immunogens
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28 September 2017
Humanized mice for modeling human infectious disease: challenges, progress, and outlook.
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28 September 2017
Glycosylation site-specific analysis of clade C HIV-1 envelope proteins
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28 September 2017
Structural and immunogenicity studies of a cleaved, stabilized envelope trimer derived from subtype A HIV-1
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28 September 2017
Antibody specificities associated with neutralization breadth in plasma from human immunodeficiency virus type 1 subtype C-infected blood donors
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28 September 2017
Neutralizing antibodies generated during natural HIV-1 infection: good news for an HIV-1 vaccine?
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28 September 2017
Introduction of exogenous epitopes in the variable regions of the human immunodeficiency virus type 1 envelope glycoprotein: effect on viral infectivity and the neutralization phenotype
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28 September 2017
HIV-1 and influenza antibodies: seeing antigens in new ways
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28 September 2017
Human immunodeficiency virus type 1 elite neutralizers: individuals with broad and potent neutralizing activity identified by using a high-throughput neutralization assay together with an analytical selection algorithm
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28 September 2017
Induction of robust cellular and humoral virus-specific adaptive immune responses in human immunodeficiency virus-infected humanized BLT mice
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28 September 2017
Enzymatic removal of mannose moieties can increase the immune response to HIV-1 gp120 in vivo
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28 September 2017
Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals
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28 September 2017
The human immunodeficiency virus type 1 envelope spike of primary viruses can suppress antibody access to variable regions
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28 September 2017
Analysis of neutralization specificities in polyclonal sera derived from human immunodeficiency virus type 1-infected individuals
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28 September 2017
Factors associated with the development of cross-reactive neutralizing antibodies during human immunodeficiency virus type 1 infection
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28 September 2017
Human immunodeficiency virus type 1 superinfection occurs despite relatively robust neutralizing antibody responses
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28 September 2017
Profiling the specificity of neutralizing antibodies in a large panel of plasmas from patients chronically infected with human immunodeficiency virus type 1 subtypes B and C.
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28 September 2017
Selective CD4+ T cell help for antibody responses to a large viral pathogen: deterministic linkage of specificities
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28 September 2017
Toward an AIDS vaccine
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28 September 2017
Glycosylation site-specific analysis of HIV envelope proteins (JR-FL and CON-S) reveals major differences in glycosylation site occupancy, glycoform profiles, and antigenic epitopes' accessibility
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28 September 2017
The challenges of eliciting neutralizing antibodies to HIV-1 and to influenza virus.
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28 September 2017
Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloning
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28 September 2017
Broad HIV-1 neutralization mediated by CD4-binding site antibodies
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28 September 2017
A comparative immunogenicity study of HIV-1 virus-like particles bearing various forms of envelope proteins, particles bearing no envelope and soluble monomeric gp120.
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28 September 2017
An HIV vaccine--evolving concepts
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28 September 2017
Rational modifications of HIV-1 envelope glycoproteins for immunogen design
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28 September 2017
Randomized, double-blind, placebo-controlled efficacy trial of a bivalent recombinant glycoprotein 120 HIV-1 vaccine among injection drug users in Bangkok, Thailand
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28 September 2017
Antibody binding is a dominant determinant of the efficiency of human immunodeficiency virus type 1 neutralization
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28 September 2017
Role of maternal autologous neutralizing antibody in selective perinatal transmission of human immunodeficiency virus type 1 escape variants
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28 September 2017
Antibody polyspecificity and neutralization of HIV-1: a hypothesis
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28 September 2017
Immunogenicity and efficacy of immunodeficiency virus-like particles pseudotyped with the G protein of vesicular stomatitis virus
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28 September 2017
Nature of nonfunctional envelope proteins on the surface of human immunodeficiency virus type 1.
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28 September 2017
Characterization of antibody responses elicited by human immunodeficiency virus type 1 primary isolate trimeric and monomeric envelope glycoproteins in selected adjuvants
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28 September 2017
Induction of neutralizing antibodies against human immunodeficiency virus type 1 primary isolates by Gag-Env pseudovirion immunization
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28 September 2017
Cardiolipin polyspecific autoreactivity in two broadly neutralizing HIV-1 antibodies.
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28 September 2017
Heterogeneity of envelope molecules expressed on primary human immunodeficiency virus type 1 particles as probed by the binding of neutralizing and nonneutralizing antibodies
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28 September 2017
Antibodies, viruses and vaccines
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28 September 2017
Enhanced presentation of major histocompatibility complex class I-restricted human immunodeficiency virus type 1 (HIV-1) Gag-specific epitopes after DNA immunization with vectors coding for vesicular stomatitis virus glycoprotein-pseudotyped HIV-1 G
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28 September 2017
Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41.
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28 September 2017
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28 September 2017
Mass spectrometric characterization of the glycosylation pattern of HIV-gp120 expressed in CHO cells
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28 September 2017
A conserved tryptophan-rich motif in the membrane-proximal region of the human immunodeficiency virus type 1 gp41 ectodomain is important for Env-mediated fusion and virus infectivity.
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28 September 2017
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7 January 2021
based on heuristic
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Molecular profile of an antibody response to HIV-1 as probed by combinatorial libraries
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28 September 2017
Cytotoxic T cells specific for a single peptide on the M2 protein of respiratory syncytial virus are the sole mediators of resistance induced by immunization with M2 encoded by a recombinant vaccinia virus
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28 September 2017
A conserved neutralizing epitope on gp41 of human immunodeficiency virus type 1
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28 September 2017
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28 September 2017
Recognition properties of a panel of human recombinant Fab fragments to the CD4 binding site of gp120 that show differing abilities to neutralize human immunodeficiency virus type 1.
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28 September 2017
Measles antibody: reevaluation of protective titers
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28 September 2017
Protection in simian immunodeficiency virus-vaccinated monkeys correlates with anti-HLA class I antibody response
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28 September 2017
HIV-specific cytolytic CD4 T cell responses during acute HIV infection predict disease outcome
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31 May 2018
ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6
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31 May 2018
Conduits mediate transport of low-molecular-weight antigen to lymph node follicles
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31 May 2018
Lack of autologous neutralizing antibody to human immunodeficiency virus type 1 (HIV-1) and macrophage tropism are associated with mother-to-infant transmission
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31 May 2018
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31 May 2018
Carbohydrate structures of the human-immunodeficiency-virus (HIV) recombinant envelope glycoprotein gp120 produced in Chinese-hamster ovary cells
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31 May 2018
Cytotoxic T lymphocyte control of acute lymphocytic choriomeningitis virus infection: interferon gamma, but not tumour necrosis factor alpha, displays antiviral activity in vivo
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31 May 2018
Efficient differentiation and function of human macrophages in humanized CSF-1 mice
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28 November 2018
Prevalence of cross-reactive HIV-1-neutralizing activity in HIV-1-infected patients with rapid or slow disease progression.
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28 November 2018
The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment.
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28 November 2018
Immune control of an SIV challenge by a T-cell-based vaccine in rhesus monkeys
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28 November 2018
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28 November 2018
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28 November 2018
Analysis of the neutralizing antibody response elicited in rabbits by repeated inoculation with trimeric HIV-1 envelope glycoproteins.
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28 November 2018
Maternal HIV-1 antibody and vertical transmission in subtype C virus infection
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28 November 2018
Mother-to-child transmission of human immunodeficiency virus type 1: correlation with neutralizing antibodies against primary isolates
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28 November 2018
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based on heuristic
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Computational protein design using flexible backbone remodeling and resurfacing: case studies in structure-based antigen design
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based on heuristic
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Spatial alterations between CD4(+) T follicular helper, B, and CD8(+) T cells during simian immunodeficiency virus infection: T/B cell homeostasis, activation, and potential mechanism for viral escape
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7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/J.CHOM.2012.09.008
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
445727
OpenCitations bibliographic resource ID
445727
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
445727
PMCID
3513329
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
445727
PubMed ID
23084910
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
445727
ResearchGate publication ID
232530660
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