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Nuclear receptors and epigenetic regulation: opportunities for nutritional targeting and disease prevention
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scholarly article
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PubMed
title
Nuclear receptors and epigenetic regulation: opportunities for nutritional targeting and disease prevention
(English)
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stated in
PubMed
main subject
disease prevention
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based on heuristic
inferred from title
author name string
D. F. Romagnolo
series ordinal
1
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stated in
Crossref
J. Zempleni
series ordinal
2
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O. I. Selmin
series ordinal
3
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stated in
Crossref
language of work or name
English
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stated in
PubMed
publication date
July 2014
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stated in
PubMed
published in
Advances in Nutrition
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stated in
PubMed
volume
5
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stated in
PubMed
issue
4
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stated in
PubMed
page(s)
373-85
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PubMed
cites work
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Feeding a protein-restricted diet during pregnancy induces altered epigenetic regulation of peroxisomal proliferator-activated receptor-α in the heart of the offspring
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7 April 2017
Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair
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7 April 2017
Downregulation of the nucleosome-binding protein 1 (NSBP1) gene can inhibit the in vitro and in vivo proliferation of prostate cancer cells
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7 April 2017
Retinoic acid receptors inhibit AP1 activation by regulating extracellular signal-regulated kinase and CBP recruitment to an AP1-responsive promoter
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7 April 2017
Translating the Histone Code
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7 April 2017
Resveratrol, a polyphenolic compound found in grapes and wine, is an agonist for the estrogen receptor
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PubMed Central
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Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors alpha and gamma
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Regulation of Estrogen Receptor α by the SET7 Lysine Methyltransferase
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7 April 2017
Direct methylation of FXR by Set7/9, a lysine methyltransferase, regulates the expression of FXR target genes
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7 April 2017
N-CoR mediates DNA methylation-dependent repression through a methyl CpG binding protein Kaiso
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7 April 2017
T:G mismatch-specific thymine-DNA glycosylase potentiates transcription of estrogen-regulated genes through direct interaction with estrogen receptor alpha
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7 April 2017
Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals
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7 April 2017
Exchange of N-CoR corepressor and Tip60 coactivator complexes links gene expression by NF-kappaB and beta-amyloid precursor protein
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7 April 2017
Combinatorial control of gene expression by nuclear receptors and coregulators
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7 April 2017
Association of CBP/p300 acetylase and thymine DNA glycosylase links DNA repair and transcription
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7 April 2017
Nuclear hormone receptors and gene expression
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7 April 2017
Omega-3 Fatty Acids and PPARgamma in Cancer
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7 April 2017
Principles for modulation of the nuclear receptor superfamily
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7 April 2017
Glucocorticoid-induced DNA demethylation and gene memory during development
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7 April 2017
What are nuclear receptor ligands?
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7 April 2017
Farnesoid X receptor antagonizes nuclear factor kappaB in hepatic inflammatory response
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7 April 2017
Determinants of coactivator LXXLL motif specificity in nuclear receptor transcriptional activation
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7 April 2017
Sensors and signals: a coactivator/corepressor/epigenetic code for integrating signal-dependent programs of transcriptional response
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7 April 2017
Adipose tissue as an endocrine organ
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7 April 2017
Estrogen receptor-alpha directs ordered, cyclical, and combinatorial recruitment of cofactors on a natural target promoter
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7 April 2017
Early life epigenetic programming and transmission of stress-induced traits in mammals: how and when can environmental factors influence traits and their transgenerational inheritance?
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28 September 2017
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28 September 2017
Nuclear receptors and chromatin: an inducible couple.
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Regulation of estrogen receptor α by histone methyltransferase SMYD2-mediated protein methylation
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28 September 2017
Non-canonical activity of retinoic acid in epigenetic control of embryonic stem cell
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28 September 2017
EGCG, a major green tea catechin suppresses breast tumor angiogenesis and growth via inhibiting the activation of HIF-1α and NFκB, and VEGF expression
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Epigenetic reactivation of estrogen receptor-α (ERα) by genistein enhances hormonal therapy sensitivity in ERα-negative breast cancer
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28 September 2017
Holocarboxylase synthetase interacts physically with euchromatic histone-lysine N-methyltransferase, linking histone biotinylation with methylation events
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28 September 2017
Hepatic lipid accumulation alters global histone h3 lysine 9 and 4 trimethylation in the peroxisome proliferator-activated receptor alpha network
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28 September 2017
Genistein demethylates the promoter of CHD5 and inhibits neuroblastoma growth in vivo
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28 September 2017
Nutraceuticals as Ligands of PPARγ
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28 September 2017
Molecular mechanisms of vitamin D action
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28 September 2017
A pleiotropic role for the orphan nuclear receptor small heterodimer partner in lipid homeostasis and metabolic pathways
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28 September 2017
EGCG suppresses prostate cancer cell growth modulating acetylation of androgen receptor by anti-histone acetyltransferase activity
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28 September 2017
Environmental estrogens differentially engage the histone methyltransferase EZH2 to increase risk of uterine tumorigenesis
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28 September 2017
Altered peroxisome-proliferator activated receptors expression in human endometrial cancer
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28 September 2017
Acute exercise remodels promoter methylation in human skeletal muscle.
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28 September 2017
Recent advances in the study on resveratrol
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28 September 2017
Epigenetic silencing of miR-34a in human prostate cancer cells and tumor tissue specimens can be reversed by BR-DIM treatment
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28 September 2017
Can soy phytoestrogens decrease DNA methylation in BRCA1 and BRCA2 oncosuppressor genes in breast cancer?
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28 September 2017
Genomic analysis of hepatic farnesoid X receptor binding sites reveals altered binding in obesity and direct gene repression by farnesoid X receptor in mice
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28 September 2017
Vitamin D and cancer: a review of molecular mechanisms
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28 September 2017
Hormonal gene regulation through DNA methylation and demethylation
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28 September 2017
Silencing of GSTP1, a prostate cancer prognostic gene, by the estrogen receptor-β and endothelial nitric oxide synthase complex
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28 September 2017
Epigenetic regulation of glucose transporter 4 by estrogen receptor β.
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28 September 2017
Biotinylation is a natural, albeit rare, modification of human histones
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28 September 2017
Comparative effects of retinoic acid, vitamin D and resveratrol alone and in combination with adenosine analogues on methylation and expression of phosphatase and tensin homologue tumour suppressor gene in breast cancer cells
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28 September 2017
Indole-3-carbinol downregulation of telomerase gene expression requires the inhibition of estrogen receptor-alpha and Sp1 transcription factor interactions within the hTERT promoter and mediates the G1 cell cycle arrest of human breast cancer cells.
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28 September 2017
Epigenetic codes of PPARγ in metabolic disease
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28 September 2017
Ligand-dependent regulation of the activity of the orphan nuclear receptor, small heterodimer partner (SHP), in the repression of bile acid biosynthetic CYP7A1 and CYP8B1 genes
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28 September 2017
Deciphering the nuclear bile acid receptor FXR paradigm
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28 September 2017
The histone modifications governing TFF1 transcription mediated by estrogen receptor
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28 September 2017
Impact of conjugated linoleic acid on bone physiology: proposed mechanism involving inhibition of adipogenesis
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28 September 2017
Histone H3K4 trimethylation by MLL3 as part of ASCOM complex is critical for NR activation of bile acid transporter genes and is downregulated in cholestasis
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28 September 2017
Epigenetics meets endocrinology
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28 September 2017
Folic acid supplementation before and during pregnancy in the Newborn Epigenetics STudy (NEST).
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28 September 2017
N-terminal phosphorylation of HP1{alpha} promotes its chromatin binding
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28 September 2017
Retracted: Epigenetic Silencing of Peroxisome Proliferator-Activated Receptor γ Is a Biomarker for Colorectal Cancer Progression and Adverse Patients' Outcome
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28 September 2017
IUGR decreases PPARγ and SETD8 Expression in neonatal rat lung and these effects are ameliorated by maternal DHA supplementation
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28 September 2017
Resveratrol prevents epigenetic silencing of BRCA-1 by the aromatic hydrocarbon receptor in human breast cancer cells
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28 September 2017
Role of epigenetic mechanisms in differential regulation of the dioxin-inducible human CYP1A1 and CYP1B1 genes
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28 September 2017
Dynamics of nuclear receptor target gene regulation.
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28 September 2017
Roles of histone H3-lysine 4 methyltransferase complexes in NR-mediated gene transcription.
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28 September 2017
Epigenetic regulatory mechanisms distinguish retinoic acid-mediated transcriptional responses in stem cells and fibroblasts
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28 September 2017
Curcumin: a novel nutritionally derived ligand of the vitamin D receptor with implications for colon cancer chemoprevention
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28 September 2017
A reexamination of the PPAR-alpha activation mode of action as a basis for assessing human cancer risks of environmental contaminants
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28 September 2017
FXR acetylation is normally dynamically regulated by p300 and SIRT1 but constitutively elevated in metabolic disease states
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PubMed Central
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28 September 2017
Sumoylated PPARalpha mediates sex-specific gene repression and protects the liver from estrogen-induced toxicity in mice
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PubMed Central
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28 September 2017
Human multipotent adipose-derived stem cells differentiate into functional brown adipocytes
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PubMed Central
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28 September 2017
Population-level transcription cycles derive from stochastic timing of single-cell transcription
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PubMed Central
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28 September 2017
Active DNA demethylation mediated by DNA glycosylases
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28 September 2017
Expression of the peroxisome proliferator activated receptor gamma gene is repressed by DNA methylation in visceral adipose tissue of mouse models of diabetes
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PubMed Central
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28 September 2017
The peroxisome proliferator-activated receptor gamma/retinoid X receptor alpha heterodimer targets the histone modification enzyme PR-Set7/Setd8 gene and regulates adipogenesis through a positive feedback loop
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28 September 2017
PPARalpha blocks glucocorticoid receptor alpha-mediated transactivation but cooperates with the activated glucocorticoid receptor alpha for transrepression on NF-kappaB
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PubMed Central
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28 September 2017
Active DNA demethylation and DNA repair
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28 September 2017
Soy isoflavones have an antiestrogenic effect and alter mammary promoter hypermethylation in healthy premenopausal women
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28 September 2017
Targeting of aryl hydrocarbon receptor-mediated activation of cyclooxygenase-2 expression by the indole-3-carbinol metabolite 3,3'-diindolylmethane in breast cancer cells
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28 September 2017
Biotinylation of histones represses transposable elements in human and mouse cells and cell lines and in Drosophila melanogaster
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28 September 2017
Selective estrogen receptor modulators and phytoestrogens
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28 September 2017
The p300 acetylase is critical for ligand-activated farnesoid X receptor (FXR) induction of SHP.
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28 September 2017
Persistent hypomethylation in the promoter of nucleosomal binding protein 1 (Nsbp1) correlates with overexpression of Nsbp1 in mouse uteri neonatally exposed to diethylstilbestrol or genistein
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28 September 2017
Quantification of ligand-regulated nuclear receptor corepressor and coactivator binding, key interactions determining ligand potency and efficacy for the thyroid hormone receptor
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PubMed Central
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28 September 2017
Transrepressive function of TLX requires the histone demethylase LSD1.
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28 September 2017
Cyclical DNA methylation of a transcriptionally active promoter
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28 September 2017
Inhibitory effect of (-)-epigallocatechin-3-gallate on lipid accumulation of 3T3-L1 cells
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28 September 2017
Epigenetics: a historical overview
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28 September 2017
Selective modulation of promoter recruitment and transcriptional activity of PPARgamma
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28 September 2017
Tissue- and nuclear receptor-specific function of the C-terminal LXXLL motif of coactivator NCoA6/AIB3 in mice
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28 September 2017
DNA methylation: the nuts and bolts of repression
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28 September 2017
Epigenetic effects of the continuous exposure to peroxisome proliferator WY-14,643 in mouse liver are dependent upon peroxisome proliferator activated receptor alpha.
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28 September 2017
Genistein sensitizes inhibitory effect of tamoxifen on the growth of estrogen receptor-positive and HER2-overexpressing human breast cancer cells
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28 September 2017
Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation.
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28 September 2017
Adamantyl-substituted retinoid-related molecules bind small heterodimer partner and modulate the Sin3A repressor.
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28 September 2017
Resveratrol regulates the expression of LXR-alpha in human macrophages
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28 September 2017
Active cytosine demethylation triggered by a nuclear receptor involves DNA strand breaks.
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28 September 2017
An estrogen receptor-alpha/p300 complex activates the BRCA-1 promoter at an AP-1 site that binds Jun/Fos transcription factors: repressive effects of p53 on BRCA-1 transcription
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28 September 2017
Reversal of hypermethylation and reactivation of p16INK4a, RARbeta, and MGMT genes by genistein and other isoflavones from soy.
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28 September 2017
Polyunsaturated fatty acid regulation of genes of lipid metabolism
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28 September 2017
Molecular mechanisms of action of the soy isoflavones includes activation of promiscuous nuclear receptors. A review
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28 September 2017
Transrepression by a liganded nuclear receptor via a bHLH activator through co-regulator switching
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28 September 2017
The methyl transferase PRMT1 functions as co-activator of farnesoid X receptor (FXR)/9-cis retinoid X receptor and regulates transcription of FXR responsive genes
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085186
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28 September 2017
Vitamin D-interacting protein 205 (DRIP205) coactivation of estrogen receptor alpha (ERalpha) involves multiple domains of both proteins
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28 September 2017
Isoflavones stimulate estrogen receptor-mediated core histone acetylation
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28 September 2017
Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines.
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28 September 2017
Agonist and chemopreventative ligands induce differential transcriptional cofactor recruitment by aryl hydrocarbon receptor
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28 September 2017
Nuclear receptors and the control of metabolism
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28 September 2017
Involvement of proteasome in the dynamic assembly of the androgen receptor transcription complex.
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28 September 2017
Estrogen receptor beta-selective transcriptional activity and recruitment of coregulators by phytoestrogens.
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28 September 2017
Resveratrol acts as a mixed agonist/antagonist for estrogen receptors alpha and beta
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28 September 2017
Maternal exposure to genistein during pregnancy increases carcinogen-induced mammary tumorigenesis in female rat offspring.
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28 September 2017
Ah receptor agonists as endocrine disruptors: antiestrogenic activity and mechanisms
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28 September 2017
Functional and physical interactions between the estrogen receptor Sp1 and nuclear aryl hydrocarbon receptor complexes
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28 September 2017
Multiple parameters determine the specificity of transcriptional response by nuclear receptors HNF-4, ARP-1, PPAR, RAR and RXR through common response elements.
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28 September 2017
Hormone-dependent regulation of BRCA1 in human breast cancer cells.
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28 September 2017
Estrogen induces a demethylation at the 5' end region of the chicken vitellogenin gene
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28 September 2017
Phorbol esters enhance 1α,25-dihydroxyvitamin D3-regulated 25-hydroxyvitamin D-24-hydroxylase (CYP24A1) gene expression through ERK-mediated phosphorylation of specific protein 3 (Sp3) in Caco-2 cells
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31 May 2018
BRCA-1 promoter hypermethylation and silencing induced by the aromatic hydrocarbon receptor-ligand TCDD are prevented by resveratrol in MCF-7 cells
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31 May 2018
Rosmarinic acid and baicalin epigenetically derepress peroxisomal proliferator-activated receptor γ in hepatic stellate cells for their antifibrotic effect
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31 May 2018
Adipocyte expression of the glucose-dependent insulinotropic polypeptide receptor involves gene regulation by PPARγ and histone acetylation
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31 May 2018
Epigenetic control of estrogen receptor expression and tumor suppressor genes is modulated by bioactive food compounds
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31 May 2018
Regulatory action on rosiglitazone by the U.S. Food and Drug Administration
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31 May 2018
Holocarboxylase synthetase is a chromatin protein and interacts directly with histone H3 to mediate biotinylation of K9 and K18
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31 May 2018
Nuclear bile acid receptor FXR protects against intestinal tumorigenesis
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31 May 2018
Molecular determinants of crosstalk between nuclear receptors and toll-like receptors.
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31 May 2018
Estrogen upregulation of BRCA1 expression with no effect on localization
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31 May 2018
Holocarboxylase synthetase synergizes with methyl CpG binding protein 2 and DNA methyltransferase 1 in the transcriptional repression of long-terminal repeats
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28 November 2018
Retraction: DNA demethylation in hormone-induced transcriptional derepression.
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28 November 2018
Expression of the nuclear bile acid receptor/farnesoid X receptor is reduced in human colon carcinoma compared to nonneoplastic mucosa independent from site and may be associated with adverse prognosis.
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28 November 2018
Epigenetic regulation of retinoic acid receptor β2 gene in the initiation of breast cancer.
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28 November 2018
Revisiting the rosiglitazone story--lessons learned
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28 November 2018
Rediscovering Waddington in the post-genomic age
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28 November 2018
Adipose tissue as an endocrine organ
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28 November 2018
Non-CpG methylation of the PGC-1alpha promoter through DNMT3B controls mitochondrial density.
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28 November 2018
Dietary soy protein isolate attenuates metabolic syndrome in rats via effects on PPAR, LXR, and SREBP signaling
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28 November 2018
Artifactual detection of biotin on histones by streptavidin
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28 November 2018
Dynamic regulation of effector protein binding to histone modifications: the biology of HP1 switching.
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28 November 2018
The ligand status of the aromatic hydrocarbon receptor modulates transcriptional activation of BRCA-1 promoter by estrogen
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28 November 2018
Dietary protein restriction of pregnant rats induces and folic acid supplementation prevents epigenetic modification of hepatic gene expression in the offspring
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28 November 2018
1,25-Dihydroxyvitamin D3 stimulates cyclic vitamin D receptor/retinoid X receptor DNA-binding, co-activator recruitment, and histone acetylation in intact osteoblasts
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28 November 2018
Modulation of oestrogen receptor signalling by association with the activated dioxin receptor
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28 November 2018
WY14,643, a peroxisome proliferator-activated receptor alpha (PPARalpha ) agonist, improves hepatic and muscle steatosis and reverses insulin resistance in lipoatrophic A-ZIP/F-1 mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085186
retrieved
28 November 2018
Characterization of the human PPARalpha promoter: identification of a functional nuclear receptor response element
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085186
retrieved
28 November 2018
Biotinylation of histones in human cells. Effects of cell proliferation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085186
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28 November 2018
Uterine adenocarcinoma in mice treated neonatally with genistein.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085186
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28 November 2018
Retinoic acid receptors interact physically and functionally with the T:G mismatch-specific thymine-DNA glycosylase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085186
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28 November 2018
Expression levels of estrogen receptor-alpha, estrogen receptor-beta, coactivators, and corepressors in breast cancer
1 reference
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
DAX1 suppresses FXR transactivity as a novel co-repressor
1 reference
stated in
PubMed
reference URL
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Methyl donor deficiency impairs fatty acid oxidation through PGC-1α hypomethylation and decreased ER-α, ERR-α, and HNF-4α in the rat liver
1 reference
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Accessory factors facilitate the binding of glucocorticoid receptor to the phosphoenolpyruvate carboxykinase gene promoter
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25022987
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Characterization of the Human PPARα Promoter: Identification of a Functional Nuclear Receptor Response Element
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25022987
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Retraction notice to: Population-level transcription cycles derive from stochastic timing of single-cell transcription
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.3945%2FAN.114.005868
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA demethylation in hormone-induced transcriptional derepression
1 reference
stated in
COCI
retrieved
30 December 2023
reference URL
https://opencitations.net/index/api/v1/citations/10.1038/NATURE08456
Identifiers
DOI
10.3945/AN.114.005868
0 references
Fatcat ID
release_d5x3xizvhfbx7hbvlb2me5lfji
0 references
PMC publication ID
4085186
1 reference
stated in
PubMed
PubMed publication ID
25022987
1 reference
stated in
PubMed
ResearchGate publication ID
263971149
0 references
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