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Functional genomic and high-content screening for target discovery and deconvolution
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scholarly article
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PubMed
title
Functional genomic and high-content screening for target discovery and deconvolution
(English)
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PubMed
main subject
drug discovery
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deconvolution
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based on heuristic
inferred from title
functional genomics
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based on heuristic
inferred from title
author name string
Susanne Heynen-Genel
series ordinal
1
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Crossref
Lars Pache
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2
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Crossref
Sumit K Chanda
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3
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Crossref
Jonathan Rosen
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4
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language of work or name
English
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PubMed
publication date
October 2012
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PubMed
published in
Expert Opinion on Drug Discovery
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PubMed
volume
7
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PubMed
issue
10
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PubMed
page(s)
955-68
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PubMed
cites work
Global landscape of HIV-human protein complexes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
21 March 2017
A cell-based high-content screening assay reveals activators and inhibitors of cancer cell invasion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
21 March 2017
Functional genomic screen for modulators of ciliogenesis and cilium length
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
21 March 2017
The IFITM proteins mediate cellular resistance to influenza A H1N1 virus, West Nile virus, and dengue virus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
21 March 2017
Human host factors required for influenza virus replication
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
21 March 2017
Statistical methods for analysis of high-throughput RNA interference screens
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
21 March 2017
Identification of host proteins required for HIV infection through a functional genomic screen
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
21 March 2017
What is a gene, post-ENCODE? History and updated definition
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
21 March 2017
Parallel chemical genetic and genome-wide RNAi screens identify cytokinesis inhibitors and targets
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
21 March 2017
Human ORFeome version 1.1: a platform for reverse proteomics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
21 March 2017
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
21 March 2017
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
7 April 2017
How cells respond to interferons
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
21 March 2017
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
21 March 2017
Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
21 March 2017
A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
21 March 2017
A genome-wide short hairpin RNA screening of jurkat T-cells for human proteins contributing to productive HIV-1 replication
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
21 March 2017
HIV-1: fifteen proteins and an RNA
2 references
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
21 March 2017
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
7 April 2017
Toward improving Caenorhabditis elegans phenome mapping with an ORFeome-based RNAi library
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
21 March 2017
The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
7 April 2017
An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
7 April 2017
Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
7 April 2017
Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
7 April 2017
A bioinformatics method identifies prominent off-targeted transcripts in RNAi screens
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
28 September 2017
Genome-wide siRNA screen for mediators of NF-κB activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
28 September 2017
Common seed analysis to identify off-target effects in siRNA screens
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
28 September 2017
A whole genome screen for HIV restriction factors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
28 September 2017
Genome-wide screening using RNA interference to study host factors in viral replication and pathogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
28 September 2017
A high-throughput platform for lentiviral overexpression screening of the human ORFeome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
28 September 2017
Phenotype recognition with combined features and random subspace classifier ensemble
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
28 September 2017
Chemical modification of small interfering RNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
28 September 2017
Uncovering the global host cell requirements for influenza virus replication via RNAi screening.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
28 September 2017
Development of an image analysis screen for estrogen receptor alpha (ERα) ligands through measurement of nuclear translocation dynamics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
28 September 2017
Identifying HIV-1 host cell factors by genome-scale RNAi screening.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
28 September 2017
Composite primary neuronal high-content screening assay for Huntington's disease incorporating non-cell-autonomous interactions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
28 September 2017
Cellular networks involved in the influenza virus life cycle
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
28 September 2017
Automated image analysis for high-content screening and analysis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
28 September 2017
Automated microscopy for high-content RNAi screening
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
28 September 2017
Genome-wide RNAi screen identifies human host factors crucial for influenza virus replication.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
28 September 2017
Cytoskeleton-based forecasting of stem cell lineage fates
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
28 September 2017
Enhanced CellClassifier: a multi-class classification tool for microscopy images
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
28 September 2017
Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
28 September 2017
Integration of multiple readouts into the z' factor for assay quality assessment
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
28 September 2017
Automatic analysis of dividing cells in live cell movies to detect mitotic delays and correlate phenotypes in time
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
28 September 2017
Population context determines cell-to-cell variability in endocytosis and virus infection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
28 September 2017
Image analysis in high-content screening
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
28 September 2017
Host cell factors in HIV replication: meta-analysis of genome-wide studies
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
28 September 2017
Off-target effects of siRNA specific for GFP
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
28 September 2017
Integrating high-content screening and ligand-target prediction to identify mechanism of action
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
28 September 2017
Genome-wide resources of endoribonuclease-prepared short interfering RNAs for specific loss-of-function studies
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
28 September 2017
Host factors exploited by retroviruses
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
28 September 2017
Off-target effects by siRNA can induce toxic phenotype
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
28 September 2017
A loss-of-function RNA interference screen for molecular targets in cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
28 September 2017
Identification of novel mammalian growth regulatory factors by genome-scale quantitative image analysis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
28 September 2017
Lentiviral and MLV based retroviral vectors for ex vivo and in vivo gene transfer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
28 September 2017
Genome-scale functional profiling of the mammalian AP-1 signaling pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
28 September 2017
Microarrays of cells expressing defined cDNAs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
28 September 2017
Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
28 September 2017
A robust high-content imaging approach for probing the mechanism of action and phenotypic outcomes of cell-cycle modulators
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
31 May 2018
A probability-based approach for the analysis of large-scale RNAi screens.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1517%2F17460441.2012.711311
retrieved
21 January 2018
High-throughput RNAi screening in cultured cells: a user's guide.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1517%2F17460441.2012.711311
retrieved
21 January 2018
A functional genomics approach to the mode of action of apratoxin A.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1517%2F17460441.2012.711311
retrieved
21 January 2018
Machine learning improves the precision and robustness of high-content screens: using nonlinear multiparametric methods to analyze screening results.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1517%2F17460441.2012.711311
retrieved
21 January 2018
Minimizing the risk of reporting false positives in large-scale RNAi screens
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1517%2F17460441.2012.711311
retrieved
21 January 2018
The use of double-stranded RNA to knock down specific gene activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954969
retrieved
28 November 2018
Genome-scale RNAi screen for host factors required for HIV replication
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22860749
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1517/17460441.2012.711311
1 reference
stated in
PubMed
PMC publication ID
3954969
1 reference
stated in
PubMed
PubMed publication ID
22860749
1 reference
stated in
PubMed
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