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Pluripotent stem cells models for Huntington's disease: prospects and challenges
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scholarly article
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stated in
PubMed
title
Pluripotent stem cells models for Huntington's disease: prospects and challenges
(English)
1 reference
stated in
PubMed
main subject
Huntington's disease
0 references
pluripotency
1 reference
based on heuristic
inferred from title
author name string
Richard L. Carter
series ordinal
1
1 reference
stated in
Crossref
Anthony W.S. Chan
series ordinal
2
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stated in
Crossref
language of work or name
English
1 reference
stated in
PubMed
publication date
20 June 2012
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stated in
PubMed
published in
Journal of Genetics and Genomics
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stated in
PubMed
volume
39
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stated in
PubMed
issue
6
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stated in
PubMed
page(s)
253-9
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stated in
PubMed
cites work
Preclinical safety of RNAi-mediated HTT suppression in the rhesus macaque as a potential therapy for Huntington's disease
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Disease-specific induced pluripotent stem cells
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Towards a transgenic model of Huntington's disease in a non-human primate
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Huntington's disease
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PubMed Central
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Characterization of Human Huntington's Disease Cell Model from Induced Pluripotent Stem Cells
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Changes in cortical and striatal neurons predict behavioral and electrophysiological abnormalities in a transgenic murine model of Huntington's disease
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Induced pluripotent stem cell lines from Huntington's disease mice undergo neuronal differentiation while showing alterations in the lysosomal pathway
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An evidence-based approach in the treatment of Huntington's disease.
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Using non-coding small RNAs to develop therapies for Huntington's disease
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Induced pluripotent stem cells--opportunities for disease modelling and drug discovery
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Induced pluripotent stem cells (iPSCs) and neurological disease modeling: progress and promises
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Modeling pathogenesis of Huntington's disease with inducible neuroprogenitor cells
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28 September 2017
Reprogramming Huntington monkey skin cells into pluripotent stem cells
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Molecular Mechanisms and Potential Therapeutical Targets in Huntington's Disease
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28 September 2017
Expression of Huntington's disease protein results in apoptotic neurons in the brains of cloned transgenic pigs
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28 September 2017
Neuroprotective mechanisms of brain-derived neurotrophic factor against 3-nitropropionic acid toxicity: therapeutic implications for Huntington's disease
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Derivation of Huntington's disease-affected human embryonic stem cell lines
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28 September 2017
Huntington's disease: progress toward effective disease-modifying treatments and a cure
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28 September 2017
Human multipotent stromal cells (MSCs) increase neurogenesis and decrease atrophy of the striatum in a transgenic mouse model for Huntington's disease
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28 September 2017
An ovine transgenic Huntington's disease model
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28 September 2017
Monkey hybrid stem cells develop cellular features of Huntington's disease
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28 September 2017
Neural stem cell systems: physiological players or in vitro entities?
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28 September 2017
Technical challenges in using human induced pluripotent stem cells to model disease
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28 September 2017
Slowed progression in models of Huntington disease by adipose stem cell transplantation
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Metabolomic profiling in LRRK2-related Parkinson's disease
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28 September 2017
Neural transplants in patients with Huntington's disease undergo disease-like neuronal degeneration
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28 September 2017
Human embryonic stem cell models of Huntington disease.
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28 September 2017
Brain-derived neurotrophic factor in neurodegenerative diseases
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Systematic behavioral evaluation of Huntington's disease transgenic and knock-in mouse models
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28 September 2017
Small molecule drug discovery for Huntington's Disease
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28 September 2017
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28 September 2017
Nonallele-specific silencing of mutant and wild-type huntingtin demonstrates therapeutic efficacy in Huntington's disease mice.
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
Mechanisms of neurodegeneration in Huntington's disease.
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28 September 2017
Full-length human mutant huntingtin with a stable polyglutamine repeat can elicit progressive and selective neuropathogenesis in BACHD mice
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28 September 2017
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28 September 2017
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28 September 2017
Alloimmunisation to donor antigens and immune rejection following foetal neural grafts to the brain in patients with Huntington's disease
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28 September 2017
Multiple pathways contribute to the pathogenesis of Huntington disease
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28 September 2017
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28 September 2017
Effect of fetal neural transplants in patients with Huntington's disease 6 years after surgery: a long-term follow-up study
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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31 May 2018
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28 November 2018
Identification and allele-specific silencing of the mutant huntingtin allele in Huntington's disease patient-derived fibroblasts.
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28 November 2018
Long-term clinical and positron emission tomography outcome of fetal striatal transplantation in Huntington's disease.
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28 November 2018
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28 November 2018
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28 November 2018
Differential loss of striatal projection systems in Huntington's disease: a quantitative immunohistochemical study
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28 November 2018
Disruption of Axonal Transport by Loss of Huntingtin or Expression of Pathogenic PolyQ Proteins in Drosophila
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28 November 2018
Transgenic rat model of Huntington's disease
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based on heuristic
inferred from PubMed ID database lookup
Differentiation of human embryonic stem cells to neural lineages in adherent culture by blocking bone morphogenetic protein signaling
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https://pubmed.ncbi.nlm.nih.gov/22749012
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Transgenic primate research paves the path to a better animal model: are we a step closer to curing inherited human genetic disorders?
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Identifiers
DOI
10.1016/J.JGG.2012.04.006
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2621312
OpenCitations bibliographic resource ID
2621312
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2621312
PMC publication ID
4075320
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2621312
PubMed publication ID
22749012
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2621312
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